# Biochemical and Molecular Research
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/biochemical-and-molecular-research/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the intricate regulation and metabolic pathways of nucleotide biosynthesis, including purine and pyrimidine biosynthesis. It explores the structure, function, and inhibition of key enzymes such as CTP synthase, IMP dehydrogenase, and dihydroorotate dehydrogenase. The cluster also delves into disorders related to nucleotide metabolism, such as Lesch-Nyhan syndrome. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12827 |
| Works | 90 |
## Topic papers all
Showing 15 of 90.
- [Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene](https://scholariq.org/papers/identification-of-the-von-hippel-lindau-disease-tumor-suppressor-gene/)
- [Pharmacogenetics: From Bench to Byte— An Update of Guidelines](https://scholariq.org/papers/pharmacogenetics-from-bench-to-byte-an-update-of-guidelines/)
- [Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma](https://scholariq.org/papers/vorasidenib-in-idh1-or-idh2-mutant-low-grade-glioma/)
- [Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy](https://scholariq.org/papers/mutant-mitochondrial-thymidine-kinase-in-mitochondrial-dna-depletion-myopathy/)
- [PYRIMIDINE AND PURINE BIOSYNTHESIS AND DEGRADATION IN PLANTS](https://scholariq.org/papers/pyrimidine-and-purine-biosynthesis-and-degradation-in-plants/)
- [Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer](https://scholariq.org/papers/targeting-pi3k-akt-mtor-pathway-in-non-small-cell-lung-cancer/)
- [Structure of the Protein Phosphatase 2A Holoenzyme](https://scholariq.org/papers/structure-of-the-protein-phosphatase-2a-holoenzyme/)
- [Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need](https://scholariq.org/papers/anti-trypanosomatid-drug-discovery-an-ongoing-challenge-and-a-continuing-need/)
- [Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC](https://scholariq.org/papers/global-metabolic-reprogramming-of-colorectal-cancer-occurs-at-adenoma-stage-and/)
- [Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer](https://scholariq.org/papers/frequency-of-i-kras-i-i-braf-i-and-i-nras-i-mutations-in-colorectal-cancer/)
- [Long-Term Intravenous Treatment of Pompe Disease With Recombinant Human α-Glucosidase From Milk](https://scholariq.org/papers/long-term-intravenous-treatment-of-pompe-disease-with-recombinant-human/)
- [Mitochondrial neurogastrointestinal encephalomyopathy: An autosomal recessive disorder due to thymidine phosphorylase mutations](https://scholariq.org/papers/mitochondrial-neurogastrointestinal-encephalomyopathy-an-autosomal-recessive/)
- [Targeting Topoisomerase I in the Era of Precision Medicine](https://scholariq.org/papers/targeting-topoisomerase-i-in-the-era-of-precision-medicine/)
- [Ambulatory evaluation of nephrolithiasis: An update of a 1980 protocol](https://scholariq.org/papers/ambulatory-evaluation-of-nephrolithiasis-an-update-of-a-1980-protocol/)
- [Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis](https://scholariq.org/papers/identification-of-a-nitroimidazo-oxazine-specific-protein-involved-in-pa-824/)
## Topic primary papers
Showing 15 of 17.
- [Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene](https://scholariq.org/papers/identification-of-the-von-hippel-lindau-disease-tumor-suppressor-gene/)
- [PYRIMIDINE AND PURINE BIOSYNTHESIS AND DEGRADATION IN PLANTS](https://scholariq.org/papers/pyrimidine-and-purine-biosynthesis-and-degradation-in-plants/)
- [Engineering Escherichia coli for efficient production of 5-aminolevulinic acid from glucose](https://scholariq.org/papers/engineering-escherichia-coli-for-efficient-production-of-5-aminolevulinic-acid/)
- [Mitochondrial Basis for Immune Deficiency](https://scholariq.org/papers/mitochondrial-basis-for-immune-deficiency/)
- [Compartmentalized biosynthesis of mycophenolic acid](https://scholariq.org/papers/compartmentalized-biosynthesis-of-mycophenolic-acid/)
- [FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney Cancer](https://scholariq.org/papers/fh-variant-pathogenicity-promotes-purine-salvage-pathway-dependence-in-kidney/)
- [Escherichia coli phnN , Encoding Ribose 1,5-Bisphosphokinase Activity (Phosphoribosyl Diphosphate Forming): Dual Role in Phosphonate Degradation and NAD Biosynthesis Pathways](https://scholariq.org/papers/i-escherichia-coli-phnn-i-encoding-ribose-1-5-bisphosphokinase-activity/)
- [New Synthetic Nitro-Pyrrolomycins as Promising Antibacterial and Anticancer Agents](https://scholariq.org/papers/new-synthetic-nitro-pyrrolomycins-as-promising-antibacterial-and-anticancer/)
- [Infiltrating lipomata of the head and neck](https://scholariq.org/papers/infiltrating-lipomata-of-the-head-and-neck/)
- [Efficacy and safety of dihydroorotate dehydrogenase (DHODH) inhibitors “leflunomide” and “teriflunomide” in Covid-19: A narrative review](https://scholariq.org/papers/efficacy-and-safety-of-dihydroorotate-dehydrogenase-dhodh-inhibitors-leflunomide/)
- [Recurrent Myoglobinuria in a Child With Mental Retardation: Phosphoglycerate Kinase Deficiency](https://scholariq.org/papers/recurrent-myoglobinuria-in-a-child-with-mental-retardation-phosphoglycerate/)
- [Characterization and inhibition study of MurA enzyme by capillary electrophoresis](https://scholariq.org/papers/characterization-and-inhibition-study-of-mura-enzyme-by-capillary/)
- [Adenine Phosphoribosyltransferase Deficiency as a Rare Cause of Renal Allograft Dysfunction](https://scholariq.org/papers/adenine-phosphoribosyltransferase-deficiency-as-a-rare-cause-of-renal-allograft/)
- [Cellular energy charge in the heart and liver of the rat. The effects of ethanol and acetaldehyde](https://scholariq.org/papers/cellular-energy-charge-in-the-heart-and-liver-of-the-rat-the-effects-of-ethanol/)
- [LIVER FUNCTION IN RHEUMATOID (CHRONIC INFECTIOUS) ARTHRITIS; PRELIMINARY REPORT](https://scholariq.org/papers/liver-function-in-rheumatoid-chronic-infectious-arthritis-preliminary-report/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.