# BRCA gene mutations in cancer

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/brca-gene-mutations-in-cancer/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on genetic research related to BRCA1 and BRCA2 mutations, and their association with breast and ovarian cancer risk. It covers topics such as genetic testing, precision medicine, genomic medicine, and the impact of mutations on cancer susceptibility. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10769 |
| Works | 314 |

## Topic papers all

Showing 15 of 314.

- [Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study](https://scholariq.org/papers/tamoxifen-for-prevention-of-breast-cancer-report-of-the-national-surgical/)
- [FinnGen provides genetic insights from a well-phenotyped isolated population](https://scholariq.org/papers/finngen-provides-genetic-insights-from-a-well-phenotyped-isolated-population/)
- [Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland](https://scholariq.org/papers/environmental-and-heritable-factors-in-the-causation-of-cancer-analyses-of/)
- [Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression](https://scholariq.org/papers/genome-wide-association-analyses-identify-44-risk-variants-and-refine-the/)
- [Integrated Genomic Characterization of Papillary Thyroid Carcinoma](https://scholariq.org/papers/integrated-genomic-characterization-of-papillary-thyroid-carcinoma/)
- [Cancer Statistics, 2002](https://scholariq.org/papers/cancer-statistics-2002/)
- [Risks of Breast, Ovarian, and Contralateral Breast Cancer for <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers](https://scholariq.org/papers/risks-of-breast-ovarian-and-contralateral-breast-cancer-for-i-brca1-i-and-i/)
- [Detection and localization of surgically resectable cancers with a multi-analyte blood test](https://scholariq.org/papers/detection-and-localization-of-surgically-resectable-cancers-with-a-multi-analyte/)
- [Gene Expression and Benefit of Chemotherapy in Women With Node-Negative, Estrogen Receptor–Positive Breast Cancer](https://scholariq.org/papers/gene-expression-and-benefit-of-chemotherapy-in-women-with-node-negative-estrogen/)
- [Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies](https://scholariq.org/papers/identification-of-novel-risk-loci-causal-insights-and-heritable-risk-for/)
- [Genome-wide association study identifies novel breast cancer susceptibility loci](https://scholariq.org/papers/genome-wide-association-study-identifies-novel-breast-cancer-susceptibility-loci/)
- [Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial](https://scholariq.org/papers/oral-poly-adp-ribose-polymerase-inhibitor-olaparib-in-patients-with-brca1-or/)
- [Five-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Segmental Mastectomy with or without Radiation in the Treatment of Breast Cancer](https://scholariq.org/papers/five-year-results-of-a-randomized-clinical-trial-comparing-total-mastectomy-and/)
- [Talazoparib in Patients with Advanced Breast Cancer and a Germline <i>BRCA</i> Mutation](https://scholariq.org/papers/talazoparib-in-patients-with-advanced-breast-cancer-and-a-germline-i-brca-i/)
- [70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer](https://scholariq.org/papers/70-gene-signature-as-an-aid-to-treatment-decisions-in-early-stage-breast-cancer/)

## Topic primary papers

Showing 15 of 91.

- [Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland](https://scholariq.org/papers/environmental-and-heritable-factors-in-the-causation-of-cancer-analyses-of/)
- [Cancer Statistics, 2002](https://scholariq.org/papers/cancer-statistics-2002/)
- [Risks of Breast, Ovarian, and Contralateral Breast Cancer for <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers](https://scholariq.org/papers/risks-of-breast-ovarian-and-contralateral-breast-cancer-for-i-brca1-i-and-i/)
- [Genome-wide association study identifies novel breast cancer susceptibility loci](https://scholariq.org/papers/genome-wide-association-study-identifies-novel-breast-cancer-susceptibility-loci/)
- [Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology](https://scholariq.org/papers/genetic-familial-high-risk-assessment-breast-ovarian-and-pancreatic-version-2/)
- [Familial Risk and Heritability of Cancer Among Twins in Nordic Countries](https://scholariq.org/papers/familial-risk-and-heritability-of-cancer-among-twins-in-nordic-countries/)
- [Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial](https://scholariq.org/papers/carboplatin-in-brca1-2-mutated-and-triple-negative-breast-cancer-brcaness/)
- [A Population-Based Study of Genes Previously Implicated in Breast Cancer](https://scholariq.org/papers/a-population-based-study-of-genes-previously-implicated-in-breast-cancer/)
- [BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors](https://scholariq.org/papers/boadicea-a-comprehensive-breast-cancer-risk-prediction-model-incorporating/)
- [Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene](https://scholariq.org/papers/germline-mutations-in-breast-and-ovarian-cancer-pedigrees-establish-rad51c-as-a/)
- [Pathology of Breast and Ovarian Cancers among <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers: Results from the Consortium of Investigators of Modifiers of <i>BRCA1</i> / <i>2</i> (CIMBA)](https://scholariq.org/papers/pathology-of-breast-and-ovarian-cancers-among-i-brca1-i-and-i-brca2-i-mutation/)
- [RAD51B in Familial Breast Cancer](https://scholariq.org/papers/rad51b-in-familial-breast-cancer/)
- [Genetic/Familial High-Risk Assessment: Breast and Ovarian](https://scholariq.org/papers/genetic-familial-high-risk-assessment-breast-and-ovarian/)
- [Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer](https://scholariq.org/papers/genome-wide-association-analysis-of-more-than-120-000-individuals-identifies-15/)
- [Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants](https://scholariq.org/papers/prediction-of-breast-cancer-risk-based-on-profiling-with-common-genetic-variants/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.