# Calcium signaling and nucleotide metabolism

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/calcium-signaling-and-nucleotide-metabolism-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 321,528 |
| Description | This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T13415 |
| Works | 14,166 |

## Topic researchers

Showing 12 of 20.

- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Shizuo Akira](https://scholariq.org/researchers/shizuo-akira/)
- [Matthias Mann](https://scholariq.org/researchers/matthias-mann/)
- [Luigi Ferrucci](https://scholariq.org/researchers/luigi-ferrucci/)
- [Hagop M. Kantarjian](https://scholariq.org/researchers/hagop-m-kantarjian/)
- [Gordon B. Mills](https://scholariq.org/researchers/gordon-b-mills/)
- [John Hardy](https://scholariq.org/researchers/john-hardy/)
- [Richard A. Flavell](https://scholariq.org/researchers/richard-a-flavell/)
- [Peter J. Barnes](https://scholariq.org/researchers/peter-j-barnes/)
- [M Snyder](https://scholariq.org/researchers/m-snyder/)
- [David Botstein](https://scholariq.org/researchers/david-botstein/)
- [Craig B. Thompson](https://scholariq.org/researchers/craig-b-thompson/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.