# Calpain Protease Function and Regulation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/calpain-protease-function-and-regulation-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 258,417 |
| Description | This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T13637 |
| Works | 13,449 |

## Topic researchers

Showing 12 of 20.

- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [John Q. Trojanowski](https://scholariq.org/researchers/john-q-trojanowski/)
- [Mark I. McCarthy](https://scholariq.org/researchers/mark-i-mccarthy/)
- [Eric Boerwinkle](https://scholariq.org/researchers/eric-boerwinkle/)
- [Peter Libby](https://scholariq.org/researchers/peter-libby/)
- [Alberto Ortíz](https://scholariq.org/researchers/alberto-ortiz/)
- [Douglas R. Green](https://scholariq.org/researchers/douglas-r-green/)
- [Bradley T. Hyman](https://scholariq.org/researchers/bradley-t-hyman/)
- [Eliezer Masliah](https://scholariq.org/researchers/eliezer-masliah/)
- [Ruedi Aebersold](https://scholariq.org/researchers/ruedi-aebersold/)
- [Steven P. Gygi](https://scholariq.org/researchers/steven-p-gygi/)
- [David Baltimore](https://scholariq.org/researchers/david-baltimore/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.