# Cancer Genomics and Diagnostics

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/cancer-genomics-and-diagnostics/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the genomic landscape of cancer, mutational signatures, intratumor heterogeneity, liquid biopsies, somatic mutations, tumor evolution, cell-free DNA, genomic instability, targeted therapy, and clonal evolution in various cancer types. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11287 |
| Works | 786 |

## Topic papers all

Showing 15 of 786.

- [Signatures of mutational processes in human cancer](https://scholariq.org/papers/signatures-of-mutational-processes-in-human-cancer/)
- [The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity](https://scholariq.org/papers/the-cancer-cell-line-encyclopedia-enables-predictive-modelling-of-anticancer/)
- [p53 Mutations in Human Cancers](https://scholariq.org/papers/p53-mutations-in-human-cancers/)
- [Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer](https://scholariq.org/papers/mutational-landscape-determines-sensitivity-to-pd-1-blockade-in-non-small-cell/)
- [Comprehensive genomic characterization defines human glioblastoma genes and core pathways](https://scholariq.org/papers/comprehensive-genomic-characterization-defines-human-glioblastoma-genes-and-core/)
- [The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups](https://scholariq.org/papers/the-genomic-and-transcriptomic-architecture-of-2-000-breast-tumours-reveals/)
- [The Immune Landscape of Cancer](https://scholariq.org/papers/the-immune-landscape-of-cancer/)
- [An Integrated Genomic Analysis of Human Glioblastoma Multiforme](https://scholariq.org/papers/an-integrated-genomic-analysis-of-human-glioblastoma-multiforme/)
- [The Somatic Genomic Landscape of Glioblastoma](https://scholariq.org/papers/the-somatic-genomic-landscape-of-glioblastoma/)
- [Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies](https://scholariq.org/papers/detection-of-circulating-tumor-dna-in-early-and-late-stage-human-malignancies/)
- [Determining cell type abundance and expression from bulk tissues with digital cytometry](https://scholariq.org/papers/determining-cell-type-abundance-and-expression-from-bulk-tissues-with-digital/)
- [Tumor mutational load predicts survival after immunotherapy across multiple cancer types](https://scholariq.org/papers/tumor-mutational-load-predicts-survival-after-immunotherapy-across-multiple/)
- [The landscape of somatic copy-number alteration across human cancers](https://scholariq.org/papers/the-landscape-of-somatic-copy-number-alteration-across-human-cancers/)
- [Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses](https://scholariq.org/papers/core-signaling-pathways-in-human-pancreatic-cancers-revealed-by-global-genomic/)
- [Comprehensive genomic characterization of squamous cell lung cancers](https://scholariq.org/papers/comprehensive-genomic-characterization-of-squamous-cell-lung-cancers/)

## Topic primary papers

Showing 15 of 272.

- [Signatures of mutational processes in human cancer](https://scholariq.org/papers/signatures-of-mutational-processes-in-human-cancer/)
- [The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity](https://scholariq.org/papers/the-cancer-cell-line-encyclopedia-enables-predictive-modelling-of-anticancer/)
- [Comprehensive genomic characterization defines human glioblastoma genes and core pathways](https://scholariq.org/papers/comprehensive-genomic-characterization-defines-human-glioblastoma-genes-and-core/)
- [The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups](https://scholariq.org/papers/the-genomic-and-transcriptomic-architecture-of-2-000-breast-tumours-reveals/)
- [Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies](https://scholariq.org/papers/detection-of-circulating-tumor-dna-in-early-and-late-stage-human-malignancies/)
- [The landscape of somatic copy-number alteration across human cancers](https://scholariq.org/papers/the-landscape-of-somatic-copy-number-alteration-across-human-cancers/)
- [Comprehensive genomic characterization of squamous cell lung cancers](https://scholariq.org/papers/comprehensive-genomic-characterization-of-squamous-cell-lung-cancers/)
- [Tumour heterogeneity and resistance to cancer therapies](https://scholariq.org/papers/tumour-heterogeneity-and-resistance-to-cancer-therapies/)
- [The repertoire of mutational signatures in human cancer](https://scholariq.org/papers/the-repertoire-of-mutational-signatures-in-human-cancer/)
- [Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients](https://scholariq.org/papers/mutational-landscape-of-metastatic-cancer-revealed-from-prospective-clinical/)
- [Oncogenic Signaling Pathways in The Cancer Genome Atlas](https://scholariq.org/papers/oncogenic-signaling-pathways-in-the-cancer-genome-atlas/)
- [Pan-cancer analysis of whole genomes](https://scholariq.org/papers/pan-cancer-analysis-of-whole-genomes/)
- [Detection and localization of surgically resectable cancers with a multi-analyte blood test](https://scholariq.org/papers/detection-and-localization-of-surgically-resectable-cancers-with-a-multi-analyte/)
- [Liquid biopsies come of age: towards implementation of circulating tumour DNA](https://scholariq.org/papers/liquid-biopsies-come-of-age-towards-implementation-of-circulating-tumour-dna/)
- [Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer](https://scholariq.org/papers/cell-of-origin-patterns-dominate-the-molecular-classification-of-10-000-tumors/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
