# Cancer, Hypoxia, and Metabolism

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/cancer-hypoxia-and-metabolism-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 2,969,024 |
| Description | This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T10631 |
| Works | 145,415 |

## Topic researchers

Showing 12 of 20.

- [Stacey Gabriel](https://scholariq.org/researchers/stacey-gabriel/)
- [Robert Tibshirani](https://scholariq.org/researchers/robert-tibshirani/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Bert Vogelstein](https://scholariq.org/researchers/bert-vogelstein/)
- [Gad Getz](https://scholariq.org/researchers/gad-getz/)
- [Elaine R. Mardis](https://scholariq.org/researchers/elaine-r-mardis/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)
- [Matthias Egger](https://scholariq.org/researchers/matthias-egger/)
- [Gregory Y.H. Lip](https://scholariq.org/researchers/gregory-y-h-lip/)
- [Matthias Mann](https://scholariq.org/researchers/matthias-mann/)
- [Róbert Langer](https://scholariq.org/researchers/robert-langer/)
- [Robert A. Weinberg](https://scholariq.org/researchers/robert-a-weinberg/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.