# Cancer Mechanisms and Therapy

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/cancer-mechanisms-and-therapy-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 228,675 |
| Description | This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | https://openalex.org/T13779 |
| Works | 23,400 |

## Topic researchers

Showing 12 of 20.

- [Stacey Gabriel](https://scholariq.org/researchers/stacey-gabriel/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Bert Vogelstein](https://scholariq.org/researchers/bert-vogelstein/)
- [Gad Getz](https://scholariq.org/researchers/gad-getz/)
- [Shizuo Akira](https://scholariq.org/researchers/shizuo-akira/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)
- [Matthias Mann](https://scholariq.org/researchers/matthias-mann/)
- [Todd R. Golub](https://scholariq.org/researchers/todd-r-golub/)
- [Matthew Meyerson](https://scholariq.org/researchers/matthew-meyerson/)
- [Chris Sander](https://scholariq.org/researchers/chris-sander/)
- [Gordon B. Mills](https://scholariq.org/researchers/gordon-b-mills/)
- [Charles M. Perou](https://scholariq.org/researchers/charles-m-perou/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.