# Cancer-related gene regulation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/cancer-related-gene-regulation/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the role of protein arginine methylation, particularly by PRMT1 and PRMT5, in mammals. It explores its involvement in histone methylation, transcriptional regulation, epigenetic control, and its implications in cancer and cell proliferation. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t13157 |
| Works | 283 |

## Topic papers all

Showing 15 of 283.

- [A genome-wide association study identifies novel risk loci for type 2 diabetes](https://scholariq.org/papers/a-genome-wide-association-study-identifies-novel-risk-loci-for-type-2-diabetes/)
- [The Mutational Landscape of Head and Neck Squamous Cell Carcinoma](https://scholariq.org/papers/the-mutational-landscape-of-head-and-neck-squamous-cell-carcinoma/)
- [Comprehensive Characterization of Cancer Driver Genes and Mutations](https://scholariq.org/papers/comprehensive-characterization-of-cancer-driver-genes-and-mutations/)
- [Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes](https://scholariq.org/papers/variant-of-transcription-factor-7-like-2-tcf7l2-gene-confers-risk-of-type-2/)
- [Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease](https://scholariq.org/papers/common-variants-at-ms4a4-ms4a6e-cd2ap-cd33-and-epha1-are-associated-with-late/)
- [Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in <i>NOTCH1</i>](https://scholariq.org/papers/exome-sequencing-of-head-and-neck-squamous-cell-carcinoma-reveals-inactivating/)
- [Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin](https://scholariq.org/papers/somatic-mutations-altering-ezh2-tyr641-in-follicular-and-diffuse-large-b-cell/)
- [Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype](https://scholariq.org/papers/targeted-disruption-of-mouse-egf-receptor-effect-of-genetic-background-on-mutant/)
- [Aberrant CpG-island methylation has non-random and tumour-type–specific patterns](https://scholariq.org/papers/aberrant-cpg-island-methylation-has-non-random-and-tumour-type-specific-patterns/)
- [Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.](https://scholariq.org/papers/inactivation-of-the-cdkn2-p16-mts1-gene-is-frequently-associated-with-aberrant/)
- [Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.](https://scholariq.org/papers/disruption-of-the-cbfa2-gene-causes-necrosis-and-hemorrhaging-in-the-central/)
- [Somatic mutant clones colonize the human esophagus with age](https://scholariq.org/papers/somatic-mutant-clones-colonize-the-human-esophagus-with-age/)
- [Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression](https://scholariq.org/papers/canonical-wnt-signaling-promotes-osteogenesis-by-directly-stimulating-runx2-gene/)
- [Epigenetic Signatures of Cigarette Smoking](https://scholariq.org/papers/epigenetic-signatures-of-cigarette-smoking/)
- [Variants conferring risk of atrial fibrillation on chromosome 4q25](https://scholariq.org/papers/variants-conferring-risk-of-atrial-fibrillation-on-chromosome-4q25/)

## Topic primary papers

Showing 15 of 27.

- [The Mutational Landscape of Head and Neck Squamous Cell Carcinoma](https://scholariq.org/papers/the-mutational-landscape-of-head-and-neck-squamous-cell-carcinoma/)
- [Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes](https://scholariq.org/papers/variant-of-transcription-factor-7-like-2-tcf7l2-gene-confers-risk-of-type-2/)
- [Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype](https://scholariq.org/papers/targeted-disruption-of-mouse-egf-receptor-effect-of-genetic-background-on-mutant/)
- [Genetic landscape of esophageal squamous cell carcinoma](https://scholariq.org/papers/genetic-landscape-of-esophageal-squamous-cell-carcinoma/)
- [Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor](https://scholariq.org/papers/identification-of-angiogenic-activity-and-the-cloning-and-expression-of-platelet/)
- [Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation](https://scholariq.org/papers/enhancer-rnas-participate-in-androgen-receptor-driven-looping-that-selectively/)
- [The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer](https://scholariq.org/papers/the-molecular-mechanism-governing-the-oncogenic-potential-of-sox2-in-breast/)
- [In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1.](https://scholariq.org/papers/in-vivo-footprint-and-methylation-analysis-by-pcr-aided-genomic-sequencing/)
- [Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis](https://scholariq.org/papers/nuclear-myh9-induced-ctnnb1-transcription-targeted-by-staurosporin-promotes/)
- [MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with <i>MTAP</i> -Deleted Cancer](https://scholariq.org/papers/mrtx1719-is-an-mta-cooperative-prmt5-inhibitor-that-exhibits-synthetic-lethality/)
- [Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer](https://scholariq.org/papers/novel-evidence-for-a-piwi-interacting-rna-pirna-as-an-oncogenic-mediator-of/)
- [Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos](https://scholariq.org/papers/asymmetric-expression-of-lincget-biases-cell-fate-in-two-cell-mouse-embryos/)
- [Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis](https://scholariq.org/papers/gene-amplification-of-the-histone-methyltransferase-setdb1-contributes-to-human/)
- [MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2](https://scholariq.org/papers/mir-27a-3p-functions-as-an-oncogene-in-gastric-cancer-by-targeting-btg2/)
- [Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor](https://scholariq.org/papers/zinc-fingers-and-homeoboxes-zhx-2-a-novel-member-of-the-zhx-family-functions-as/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.