# Cancer Research and Treatments

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/cancer-research-and-treatments/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the use of engineered bacteria, particularly Salmonella typhimurium, for targeted cancer therapy. The research involves various strategies such as tumor-specific colonization, gene delivery, immunotherapy, and metabolic manipulation to induce tumor regression and enhance anti-tumor immunity. Fluorescent protein imaging is utilized to visualize tumor growth, metastasis, and angiogenesis in live animals. Additionally, the cluster explores the use of bacterial vectors for gene therapy and the potential of arginine deprivation as a targeted therapy for certain cancers. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12996 |
| Works | 194 |

## Topic papers all

Showing 15 of 194.

- [Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer](https://scholariq.org/papers/pembrolizumab-for-the-treatment-of-non-small-cell-lung-cancer/)
- [Pembrolizumab for Early Triple-Negative Breast Cancer](https://scholariq.org/papers/pembrolizumab-for-early-triple-negative-breast-cancer/)
- [The human tumor microbiome is composed of tumor type–specific intracellular bacteria](https://scholariq.org/papers/the-human-tumor-microbiome-is-composed-of-tumor-type-specific-intracellular/)
- [Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer](https://scholariq.org/papers/incorporation-of-bevacizumab-in-the-primary-treatment-of-ovarian-cancer/)
- [Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine](https://scholariq.org/papers/potential-role-of-intratumor-bacteria-in-mediating-tumor-resistance-to-the/)
- [<i>TERT</i> promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal](https://scholariq.org/papers/i-tert-i-promoter-mutations-occur-frequently-in-gliomas-and-a-subset-of-tumors/)
- [Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer](https://scholariq.org/papers/initial-therapy-with-folfoxiri-and-bevacizumab-for-metastatic-colorectal-cancer/)
- [Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer](https://scholariq.org/papers/role-of-a-p53-polymorphism-in-the-development-of-human-papilloma-virus/)
- [Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label, phase 3 trial](https://scholariq.org/papers/bevacizumab-for-newly-diagnosed-pleural-mesothelioma-in-the-mesothelioma-avastin/)
- [Phase I Trial of Interleukin-12 Plasmid Electroporation in Patients With Metastatic Melanoma](https://scholariq.org/papers/phase-i-trial-of-interleukin-12-plasmid-electroporation-in-patients-with/)
- [<i>Fusobacterium nucleatum</i>and T Cells in Colorectal Carcinoma](https://scholariq.org/papers/i-fusobacterium-nucleatum-i-and-t-cells-in-colorectal-carcinoma/)
- [Association of Maximal Extent of Resection of Contrast-Enhanced and Non–Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma](https://scholariq.org/papers/association-of-maximal-extent-of-resection-of-contrast-enhanced-and-non-contrast/)
- [Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy](https://scholariq.org/papers/increased-tumor-glycolysis-characterizes-immune-resistance-to-adoptive-t-cell/)
- [Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer](https://scholariq.org/papers/final-results-from-prime-randomized-phase-iii-study-of-panitumumab-with-folfox4/)
- [Safety and Survival With GVAX Pancreas Prime and <i>Listeria Monocytogenes</i>–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer](https://scholariq.org/papers/safety-and-survival-with-gvax-pancreas-prime-and-i-listeria-monocytogenes-i/)

## Topic primary papers

Showing 15 of 27.

- [Intratumoral injection of <i>Clostridium novyi</i> -NT spores induces antitumor responses](https://scholariq.org/papers/intratumoral-injection-of-i-clostridium-novyi-i-nt-spores-induces-antitumor/)
- [Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer](https://scholariq.org/papers/fusobacterium-nucleatum-enhances-the-efficacy-of-pd-l1-blockade-in-colorectal/)
- [An Overview of Cancer Treatment Modalities](https://scholariq.org/papers/an-overview-of-cancer-treatment-modalities/)
- [Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens](https://scholariq.org/papers/gut-microbes-define-liver-cancer-risk-in-mice-exposed-to-chemical-and-viral/)
- [An Orthotopic Model of Human Osteosarcoma Growth and Spontaneous Pulmonary Metastasis](https://scholariq.org/papers/an-orthotopic-model-of-human-osteosarcoma-growth-and-spontaneous-pulmonary/)
- [Plasticity of cancer cell invasion: Patterns and mechanisms](https://scholariq.org/papers/plasticity-of-cancer-cell-invasion-patterns-and-mechanisms/)
- [Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study](https://scholariq.org/papers/safety-and-effectiveness-of-sgm-101-a-fluorescent-antibody-targeting/)
- [Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice.](https://scholariq.org/papers/development-of-an-orthotopic-model-to-study-the-biology-and-therapy-of-primary/)
- [Strain‐specific probiotic (microbial cell preparation) and omega‐3 fatty acid in modulating quality of life and inflammatory markers in colorectal cancer patients: a randomized controlled trial](https://scholariq.org/papers/strain-specific-probiotic-microbial-cell-preparation-and-omega-3-fatty-acid-in/)
- [Methioninase cancer gene therapy with selenomethionine as suicide prodrug substrate.](https://scholariq.org/papers/methioninase-cancer-gene-therapy-with-selenomethionine-as-suicide-prodrug/)
- [Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis](https://scholariq.org/papers/caffeine-suppresses-metastasis-in-a-transgenic-mouse-model-a-prototype-molecule/)
- [Engineering Escherichia coli Nissle 1917 as a microbial chassis for therapeutic and industrial applications](https://scholariq.org/papers/engineering-escherichia-coli-nissle-1917-as-a-microbial-chassis-for-therapeutic/)
- [Postoperative Infection May Influence Survival in Patients With Glioblastoma: Simply a Myth?](https://scholariq.org/papers/postoperative-infection-may-influence-survival-in-patients-with-glioblastoma/)
- [Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218](https://scholariq.org/papers/predictive-blood-based-biomarkers-in-patients-with-epithelial-ovarian-cancer/)
- [Probiotic Engineering and Targeted Sonoimmuno‐Therapy Augmented by STING Agonist](https://scholariq.org/papers/probiotic-engineering-and-targeted-sonoimmuno-therapy-augmented-by-sting-agonist/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.