# Catalytic C–H Functionalization Methods
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/catalytic-c-h-functionalization-methods/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the transition-metal-catalyzed functionalization of carbon-hydrogen (C–H) bonds, enabling the formation of carbon-carbon bonds, arylation, and synthesis of heterocycles. The research also explores applications in drug synthesis and oxidative coupling reactions. |
| Domain | Physical Sciences |
| Field | Chemistry |
| OpenAlex ID | t10354 |
| Works | 52 |
## Topic papers all
Showing 15 of 52.
- [Transition metal-catalyzed ketone-directed or mediated C–H functionalization](https://scholariq.org/papers/transition-metal-catalyzed-ketone-directed-or-mediated-c-h-functionalization/)
- [Site-specific allylic C–H bond functionalization with a copper-bound N-centred radical](https://scholariq.org/papers/site-specific-allylic-c-h-bond-functionalization-with-a-copper-bound-n-centred/)
- [Highly Enantioselective Catalytic Fluorination and Chlorination Reactions of Carbonyl Compounds Capable of Two‐Point Binding](https://scholariq.org/papers/highly-enantioselective-catalytic-fluorination-and-chlorination-reactions-of/)
- [Rhodium-Catalyzed Asymmetric C–H Functionalization Reactions](https://scholariq.org/papers/rhodium-catalyzed-asymmetric-c-h-functionalization-reactions/)
- [Catalytic C(sp3)−H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ](https://scholariq.org/papers/catalytic-c-sp-sup-3-sup-h-arylation-of-free-primary-amines-with-an-i-exo-i/)
- [Pyridine-Boryl Radical-Catalyzed \[2π + 2σ\] Cycloaddition of Bicyclo\[1.1.0\]butanes with Alkenes](https://scholariq.org/papers/pyridine-boryl-radical-catalyzed-2-2-cycloaddition-of-bicyclo-1-1-0-butanes-with/)
- [In Situ Generation of Palladium Nanoparticles: A Simple and Highly Active Protocol for Oxygen-Promoted Ligand-Free Suzuki Coupling Reaction of Aryl Chlorides](https://scholariq.org/papers/in-situ-generation-of-palladium-nanoparticles-a-simple-and-highly-active/)
- [Transition Metal Catalysis in Fluorous Media: Practical Application of a New Immobilization Principle to Rhodium-Catalyzed Hydroborations of Alkenes and Alkynes](https://scholariq.org/papers/transition-metal-catalysis-in-fluorous-media-practical-application-of-a-new/)
- [Cyclopalladated ferrocenylimines: efficient catalysts for homocoupling and Sonogashira reaction of terminal alkynes](https://scholariq.org/papers/cyclopalladated-ferrocenylimines-efficient-catalysts-for-homocoupling-and/)
- [Sulfonamides as new hydrogen atom transfer (HAT) catalysts for photoredox allylic and benzylic C–H arylations](https://scholariq.org/papers/sulfonamides-as-new-hydrogen-atom-transfer-hat-catalysts-for-photoredox-allylic/)
- [Carbon Dioxide-Mediated C(sp3)–H Arylation of Amine Substrates](https://scholariq.org/papers/carbon-dioxide-mediated-c-sp-sup-3-sup-h-arylation-of-amine-substrates/)
- [A simple and efficient protocol for a palladium-catalyzed ligand-free Suzuki reaction at room temperature in aqueous DMF](https://scholariq.org/papers/a-simple-and-efficient-protocol-for-a-palladium-catalyzed-ligand-free-suzuki/)
- [Aerobic Ligand‐Free Suzuki Coupling Reaction of Aryl Chlorides Catalyzed by In Situ Generated Palladium Nanoparticles at Room Temperature](https://scholariq.org/papers/aerobic-ligand-free-suzuki-coupling-reaction-of-aryl-chlorides-catalyzed-by-i-in/)
- [Decarboxylative acylation of indolines with α-keto acids under palladium catalysis: a facile strategy for the synthesis of 7-substituted indoles](https://scholariq.org/papers/decarboxylative-acylation-of-indolines-with-keto-acids-under-palladium-catalysis/)
- [Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes](https://scholariq.org/papers/oxidatively-induced-reductive-elimination-exploring-the-scope-and-catalyst/)
## Topic primary papers
Showing 15 of 24.
- [Transition metal-catalyzed ketone-directed or mediated C–H functionalization](https://scholariq.org/papers/transition-metal-catalyzed-ketone-directed-or-mediated-c-h-functionalization/)
- [Site-specific allylic C–H bond functionalization with a copper-bound N-centred radical](https://scholariq.org/papers/site-specific-allylic-c-h-bond-functionalization-with-a-copper-bound-n-centred/)
- [Rhodium-Catalyzed Asymmetric C–H Functionalization Reactions](https://scholariq.org/papers/rhodium-catalyzed-asymmetric-c-h-functionalization-reactions/)
- [Catalytic C(sp3)−H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ](https://scholariq.org/papers/catalytic-c-sp-sup-3-sup-h-arylation-of-free-primary-amines-with-an-i-exo-i/)
- [Carbon Dioxide-Mediated C(sp3)–H Arylation of Amine Substrates](https://scholariq.org/papers/carbon-dioxide-mediated-c-sp-sup-3-sup-h-arylation-of-amine-substrates/)
- [Decarboxylative acylation of indolines with α-keto acids under palladium catalysis: a facile strategy for the synthesis of 7-substituted indoles](https://scholariq.org/papers/decarboxylative-acylation-of-indolines-with-keto-acids-under-palladium-catalysis/)
- [Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes](https://scholariq.org/papers/oxidatively-induced-reductive-elimination-exploring-the-scope-and-catalyst/)
- [Merging NiH Catalysis and Inner-Sphere Metal-Nitrenoid Transfer for Hydroamidation of Alkynes](https://scholariq.org/papers/merging-nih-catalysis-and-inner-sphere-metal-nitrenoid-transfer-for/)
- [Highly Enantioselective Nickel‐Catalyzed Intramolecular Reductive Cyclization of Alkynones](https://scholariq.org/papers/highly-enantioselective-nickel-catalyzed-intramolecular-reductive-cyclization-of/)
- [Chelation versus Non‐Chelation Control in the Stereoselective Alkenyl sp2 C−H Bond Functionalization Reaction](https://scholariq.org/papers/chelation-versus-non-chelation-control-in-the-stereoselective-alkenyl-sp-sup-2/)
- [PhI(OCOCF3)2-Mediated C–C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3-Arylquinolin-2-ones](https://scholariq.org/papers/phi-ococf-sub-3-sub-sub-2-sub-mediated-c-c-bond-formation-concomitant-with-a-1-2/)
- [Ru(II)-Catalyzed Selective C–H Amination of Xanthones and Chromones with Sulfonyl Azides: Synthesis and Anticancer Evaluation](https://scholariq.org/papers/ru-ii-catalyzed-selective-c-h-amination-of-xanthones-and-chromones-with-sulfonyl/)
- [Micellar Catalysis for Ruthenium(II)‐Catalyzed C−H Arylation: Weak‐Coordination‐Enabled C−H Activation in H2O](https://scholariq.org/papers/micellar-catalysis-for-ruthenium-ii-catalyzed-c-h-arylation-weak-coordination/)
- [One‐Pot Synthesis of Highly Fluorescent Pyrido\[1,2‐a\]indole Derivatives through CH/NH Activation: Photophysical Investigations and Application in Cell Imaging](https://scholariq.org/papers/one-pot-synthesis-of-highly-fluorescent-pyrido-1-2-i-a-i-indole-derivatives/)
- [Metal‐Free Decarboxylative Cyclization/Ring Expansion: Construction of Five‐, Six‐, and Seven‐Membered Heterocycles from 2‐Alkynyl Benzaldehydes and Cyclic Amino Acids](https://scholariq.org/papers/metal-free-decarboxylative-cyclization-ring-expansion-construction-of-five-six/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.