# Chemical Reactions and Isotopes

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/chemical-reactions-and-isotopes-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 632,961 |
| Description | This cluster of papers focuses on the use of deuterium and tritium labeling, hydrogen isotope exchange, and catalysis in drug discovery and development. It explores applications in medicinal chemistry, metabolism studies, and the incorporation of deuterium into pharmaceutical compounds. The research also highlights the use of iridium-catalyzed reactions and the impact of deuterium substitution on drug pharmacokinetics. |
| Domain | Life Sciences |
| Field | Pharmacology, Toxicology and Pharmaceutics |
| OpenAlex ID | https://openalex.org/T13561 |
| Works | 96,247 |

## Topic researchers

Showing 12 of 20.

- [Christopher J L Murray](https://scholariq.org/researchers/christopher-j-l-murray/)
- [Matthias Mann](https://scholariq.org/researchers/matthias-mann/)
- [Stephen B. Baylin](https://scholariq.org/researchers/stephen-b-baylin/)
- [Willem M. de Vos](https://scholariq.org/researchers/willem-m-de-vos/)
- [Ettore Beghi](https://scholariq.org/researchers/ettore-beghi/)
- [Adrian L. Harris](https://scholariq.org/researchers/adrian-l-harris/)
- [Laurence Zitvogel](https://scholariq.org/researchers/laurence-zitvogel/)
- [Frank J. Gonzalez](https://scholariq.org/researchers/frank-j-gonzalez/)
- [Rüssel J. Reiter](https://scholariq.org/researchers/russel-j-reiter/)
- [Marcus E. Raichle](https://scholariq.org/researchers/marcus-e-raichle/)
- [James M. Tiedje](https://scholariq.org/researchers/james-m-tiedje/)
- [Claudiu T. Supuran](https://scholariq.org/researchers/claudiu-t-supuran/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.