# Chemical Synthesis and Analysis
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/chemical-synthesis-and-analysis/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on peptide synthesis, foldamers, amide bond formation, protein-protein interactions, diversity-oriented synthesis, and macrocycles in the context of drug discovery. It explores strategies for the design, synthesis, and application of peptides as therapeutic agents, as well as the development of novel methods for solid-phase peptide synthesis and chemical ligation. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10911 |
| Works | 68 |
## Topic papers all
Showing 15 of 68.
- [Protein Chemical Synthesis by Ligation of Peptide Hydrazides](https://scholariq.org/papers/protein-chemical-synthesis-by-ligation-of-peptide-hydrazides/)
- [Parathyroid hormone-related protein purified from a human lung cancer cell line.](https://scholariq.org/papers/parathyroid-hormone-related-protein-purified-from-a-human-lung-cancer-cell-line/)
- [Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs](https://scholariq.org/papers/modern-approaches-for-asymmetric-construction-of-carbon-fluorine-quaternary/)
- [Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions](https://scholariq.org/papers/genetic-encoding-of-bicyclononynes-and-i-trans-i-cyclooctenes-for-site-specific/)
- [Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic](https://scholariq.org/papers/structure-of-the-nociceptin-orphanin-fq-receptor-in-complex-with-a-peptide/)
- [Herstellung von α‐Aminosäureestern durch Alkoholyse der Methylester](https://scholariq.org/papers/herstellung-von-aminosaureestern-durch-alkoholyse-der-methylester/)
- [Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials](https://scholariq.org/papers/decarboxylative-alkylation-for-site-selective-bioconjugation-of-native-proteins/)
- [Endogenous d‐Serine in Rat Brain: N‐Methyl‐d‐Aspartate Receptor‐Related Distribution and Aging](https://scholariq.org/papers/endogenous-scp-d-scp-serine-in-rat-brain-i-n-i-methyl-scp-d-scp-aspartate/)
- [Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice](https://scholariq.org/papers/chromosomal-mapping-of-mouse-myelin-basic-protein-gene-and-structure-and/)
- [Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids](https://scholariq.org/papers/ring-opening-polymerization-of-amino-acids-advances-in-synthesis-architecture/)
- [Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion](https://scholariq.org/papers/peptide-arrays-on-cellulose-support-spot-synthesis-a-time-and-cost-efficient/)
- [Parallel Synthesis and Screening of a Solid Phase Carbohydrate Library](https://scholariq.org/papers/parallel-synthesis-and-screening-of-a-solid-phase-carbohydrate-library/)
- [Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-kinase in Cell Culture](https://scholariq.org/papers/novel-rp-camps-analogs-as-tools-for-inhibition-of-camp-kinase-in-cell-culture/)
- [Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold](https://scholariq.org/papers/refactoring-the-silent-spectinabilin-gene-cluster-using-a-plug-and-play-scaffold/)
- [Expanding the Genetic Code for Biological Studies](https://scholariq.org/papers/expanding-the-genetic-code-for-biological-studies/)
## Topic primary papers
- [Protein Chemical Synthesis by Ligation of Peptide Hydrazides](https://scholariq.org/papers/protein-chemical-synthesis-by-ligation-of-peptide-hydrazides/)
- [Parathyroid hormone-related protein purified from a human lung cancer cell line.](https://scholariq.org/papers/parathyroid-hormone-related-protein-purified-from-a-human-lung-cancer-cell-line/)
- [Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice](https://scholariq.org/papers/chromosomal-mapping-of-mouse-myelin-basic-protein-gene-and-structure-and/)
- [Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion](https://scholariq.org/papers/peptide-arrays-on-cellulose-support-spot-synthesis-a-time-and-cost-efficient/)
- [Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-kinase in Cell Culture](https://scholariq.org/papers/novel-rp-camps-analogs-as-tools-for-inhibition-of-camp-kinase-in-cell-culture/)
- [MY-1250, a major metabolite of the anti-allergic drug repirinast, induces phosphorylation of a 78-kDa protein in rat mast cells](https://scholariq.org/papers/my-1250-a-major-metabolite-of-the-anti-allergic-drug-repirinast-induces/)
- [Synthetic Peptides as Protein Mimics](https://scholariq.org/papers/synthetic-peptides-as-protein-mimics/)
- [Synthesis of Primary Allylic Amines](https://scholariq.org/papers/synthesis-of-primary-allylic-amines/)
- [Synthesis and characterization of rhenium(VII) alkylidene alkylidyne complexes of the type Re(CR')(CHR')(OR)2 and related species](https://scholariq.org/papers/synthesis-and-characterization-of-rhenium-vii-alkylidene-alkylidyne-complexes-of/)
- [Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization](https://scholariq.org/papers/enhancing-the-cell-permeability-and-metabolic-stability-of-peptidyl-drugs-by/)
- [Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening](https://scholariq.org/papers/prioritizing-multiple-therapeutic-targets-in-parallel-using-automated-dna/)
- [A General Strategy for the Synthesis of Cyclic N-Aryl Hydroxamic Acids via Partial Nitro Group Reduction](https://scholariq.org/papers/a-general-strategy-for-the-synthesis-of-cyclic-i-n-i-aryl-hydroxamic-acids-via/)
- [Synthesis of ortho-substituted nitroaromatics via improved Negishi coupling conditions](https://scholariq.org/papers/synthesis-of-ortho-substituted-nitroaromatics-via-improved-negishi-coupling/)
- [Structural and biological aspects of natural bridged macrobicyclic peptides from marine resources](https://scholariq.org/papers/structural-and-biological-aspects-of-natural-bridged-macrobicyclic-peptides-from/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.