# Chemokine receptors and signaling

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/chemokine-receptors-and-signaling/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of chemokine receptors in cancer metastasis, focusing on their involvement in tumor development, immune responses, inflammation, angiogenesis, and cell migration. The research also highlights the potential of chemokine receptors as therapeutic targets in cancer treatment. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t11532 |
| Works | 141 |

## Topic papers all

Showing 15 of 141.

- [The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer](https://scholariq.org/papers/the-role-of-tumoral-foxp3-on-cell-proliferation-migration-and-invasion-in/)
- [Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice](https://scholariq.org/papers/absence-of-monocyte-chemoattractant-protein-1-reduces-atherosclerosis-in-low/)
- [The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract](https://scholariq.org/papers/the-chemokine-receptor-cxcr4-is-essential-for-vascularization-of-the/)
- [Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial](https://scholariq.org/papers/effect-of-interleukin-1-inhibition-with-canakinumab-on-incident-lung-cancer-in/)
- [Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques](https://scholariq.org/papers/monocyte-subsets-differentially-employ-ccr2-ccr5-and-cx3cr1-to-accumulate-within/)
- [Targeted Anticytokine Therapy in Patients With Chronic Heart Failure](https://scholariq.org/papers/targeted-anticytokine-therapy-in-patients-with-chronic-heart-failure/)
- [A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis](https://scholariq.org/papers/a-cxcl1-paracrine-network-links-cancer-chemoresistance-and-metastasis/)
- [Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist](https://scholariq.org/papers/rapid-mobilization-of-murine-and-human-hematopoietic-stem-and-progenitor-cells/)
- [Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients](https://scholariq.org/papers/expression-of-specific-chemokines-and-chemokine-receptors-in-the-central-nervous/)
- [Macrophages in Tumor Microenvironments and the Progression of Tumors](https://scholariq.org/papers/macrophages-in-tumor-microenvironments-and-the-progression-of-tumors/)
- [Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis](https://scholariq.org/papers/abrogation-of-tgf-signaling-in-mammary-carcinomas-recruits-gr-1-cd11b-myeloid/)
- [Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression](https://scholariq.org/papers/human-endothelial-cells-express-ccr2-and-respond-to-mcp-1-direct-role-of-mcp-1/)
- [Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function](https://scholariq.org/papers/phosphodiesterase-5-inhibition-augments-endogenous-antitumor-immunity-by/)
- [An Alternatively Spliced Variant of CXCR3 Mediates the Inhibition of Endothelial Cell Growth Induced by IP-10, Mig, and I-TAC, and Acts as Functional Receptor for Platelet Factor 4](https://scholariq.org/papers/an-alternatively-spliced-variant-of-cxcr3-mediates-the-inhibition-of-endothelial/)
- [Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC](https://scholariq.org/papers/ubiquitous-activation-of-ras-and-jak-stat-pathways-in-human-hcc/)

## Topic primary papers

Showing 15 of 56.

- [Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice](https://scholariq.org/papers/absence-of-monocyte-chemoattractant-protein-1-reduces-atherosclerosis-in-low/)
- [The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract](https://scholariq.org/papers/the-chemokine-receptor-cxcr4-is-essential-for-vascularization-of-the/)
- [Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques](https://scholariq.org/papers/monocyte-subsets-differentially-employ-ccr2-ccr5-and-cx3cr1-to-accumulate-within/)
- [A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis](https://scholariq.org/papers/a-cxcl1-paracrine-network-links-cancer-chemoresistance-and-metastasis/)
- [Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist](https://scholariq.org/papers/rapid-mobilization-of-murine-and-human-hematopoietic-stem-and-progenitor-cells/)
- [Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients](https://scholariq.org/papers/expression-of-specific-chemokines-and-chemokine-receptors-in-the-central-nervous/)
- [Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression](https://scholariq.org/papers/human-endothelial-cells-express-ccr2-and-respond-to-mcp-1-direct-role-of-mcp-1/)
- [An Alternatively Spliced Variant of CXCR3 Mediates the Inhibition of Endothelial Cell Growth Induced by IP-10, Mig, and I-TAC, and Acts as Functional Receptor for Platelet Factor 4](https://scholariq.org/papers/an-alternatively-spliced-variant-of-cxcr3-mediates-the-inhibition-of-endothelial/)
- [Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection](https://scholariq.org/papers/requirement-of-the-chemokine-receptor-cxcr3-for-acute-allograft-rejection/)
- [A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors](https://scholariq.org/papers/a-small-molecule-antagonist-of-cxcr4-inhibits-intracranial-growth-of-primary/)
- [Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells](https://scholariq.org/papers/vascular-endothelial-growth-factor-and-basic-fibroblast-growth-factor-induce/)
- [Interleukin 6 and Interleukin 8 as Potential Biomarkers for Oral Cavity and Oropharyngeal Squamous Cell Carcinoma](https://scholariq.org/papers/interleukin-6-and-interleukin-8-as-potential-biomarkers-for-oral-cavity-and/)
- [Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction](https://scholariq.org/papers/interleukin-6-released-by-colon-cancer-associated-fibroblasts-is-critical-for/)
- [Active participation of CCR5+CD8+ T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease](https://scholariq.org/papers/active-participation-of-ccr5-cd8-t-lymphocytes-in-the-pathogenesis-of-liver/)
- [The role of CXCL family members in different diseases](https://scholariq.org/papers/the-role-of-cxcl-family-members-in-different-diseases/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.