# Cholesterol and Lipid Metabolism **Type:** Topics **Canonical URL:** https://scholariq.org/topics/cholesterol-and-lipid-metabolism/ ## Facts | Field | Value | | --- | --- | | Description | This cluster of papers focuses on the intricate mechanisms of cholesterol metabolism, including the roles of key regulators such as LXR and SREBP, the impact on atherosclerosis, and the involvement of specific proteins like ABCA1 in processes such as cholesterol efflux from cells. It also delves into the effects of phytosterols on lipid levels and the interplay between cholesterol homeostasis and inflammation in conditions like atherosclerosis. | | Domain | Health Sciences | | Field | Medicine | | OpenAlex ID | t11618 | | Works | 184 | ## Topic papers all Showing 15 of 184. - [Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes](https://scholariq.org/papers/ezetimibe-added-to-statin-therapy-after-acute-coronary-syndromes/) - [Biological, clinical and population relevance of 95 loci for blood lipids](https://scholariq.org/papers/biological-clinical-and-population-relevance-of-95-loci-for-blood-lipids/) - [Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society](https://scholariq.org/papers/familial-hypercholesterolaemia-is-underdiagnosed-and-undertreated-in-the-general/) - [Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease](https://scholariq.org/papers/common-variants-at-abca7-ms4a6a-ms4a4e-epha1-cd33-and-cd2ap-are-associated-with/) - [Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway](https://scholariq.org/papers/dependency-of-a-therapy-resistant-state-of-cancer-cells-on-a-lipid-peroxidase/) - [Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis](https://scholariq.org/papers/cholesterol-efflux-capacity-high-density-lipoprotein-function-and/) - [Polyunsaturated fatty acids and their metabolites in brain function and disease](https://scholariq.org/papers/polyunsaturated-fatty-acids-and-their-metabolites-in-brain-function-and-disease/) - [Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice](https://scholariq.org/papers/absence-of-monocyte-chemoattractant-protein-1-reduces-atherosclerosis-in-low/) - [Can dietary beta-carotene materially reduce human cancer rates?](https://scholariq.org/papers/can-dietary-beta-carotene-materially-reduce-human-cancer-rates/) - [Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia](https://scholariq.org/papers/simvastatin-with-or-without-ezetimibe-in-familial-hypercholesterolemia/) - [The power of genetic diversity in genome-wide association studies of lipids](https://scholariq.org/papers/the-power-of-genetic-diversity-in-genome-wide-association-studies-of-lipids/) - [Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society](https://scholariq.org/papers/homozygous-familial-hypercholesterolaemia-new-insights-and-guidance-for/) - [Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.](https://scholariq.org/papers/cyclooxygenase-2-is-associated-with-the-macula-densa-of-rat-kidney-and-increases/) - [Cholesterol gallstone disease](https://scholariq.org/papers/cholesterol-gallstone-disease/) - [Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human](https://scholariq.org/papers/dysfunction-of-lipid-sensor-gpr120-leads-to-obesity-in-both-mouse-and-human/) ## Topic primary papers Showing 15 of 58. - [Effects of a Dietary Portfolio of Cholesterol-Lowering Foods vs Lovastatin on Serum Lipids and C-Reactive Protein](https://scholariq.org/papers/effects-of-a-dietary-portfolio-of-cholesterol-lowering-foods-vs-lovastatin-on/) - [Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease](https://scholariq.org/papers/plant-sterols-and-plant-stanols-in-the-management-of-dyslipidaemia-and/) - [The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages](https://scholariq.org/papers/the-ability-to-promote-efflux-via-abca1-determines-the-capacity-of-serum/) - [Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels](https://scholariq.org/papers/multiple-rare-variants-in-i-npc1l1-i-associated-with-reduced-sterol-absorption/) - [Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!](https://scholariq.org/papers/key-stages-in-mammary-gland-development-secretory-activation-in-the-mammary/) - [Metabolic effects of plant sterols and stanols (Review)](https://scholariq.org/papers/metabolic-effects-of-plant-sterols-and-stanols-review/) - [Plant Stanol and Sterol Esters in the Control of Blood Cholesterol Levels: Mechanism and Safety Aspects](https://scholariq.org/papers/plant-stanol-and-sterol-esters-in-the-control-of-blood-cholesterol-levels/) - [Effects of plant sterols and stanols on intestinal cholesterol metabolism: Suggested mechanisms from past to present](https://scholariq.org/papers/effects-of-plant-sterols-and-stanols-on-intestinal-cholesterol-metabolism/) - [Cholesterol-Lowering Nutraceuticals and Functional Foods](https://scholariq.org/papers/cholesterol-lowering-nutraceuticals-and-functional-foods/) - [The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease](https://scholariq.org/papers/the-lxr-agonist-to901317-selectively-lowers-hippocampal-a-42-and-improves-memory/) - [ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer](https://scholariq.org/papers/abca-transporter-gene-expression-and-poor-outcome-in-epithelial-ovarian-cancer/) - [Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux](https://scholariq.org/papers/differential-effects-of-hdl-subpopulations-on-cellular-abca1-and-sr-bi-mediated/) - [Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation](https://scholariq.org/papers/plant-sterols-and-stanols-effects-on-mixed-micellar-composition-and-lxr-target/) - [Impact of Cholesterol Metabolism in Immune Cell Function and Atherosclerosis](https://scholariq.org/papers/impact-of-cholesterol-metabolism-in-immune-cell-function-and-atherosclerosis/) - [A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol](https://scholariq.org/papers/a-sensitive-assay-for-abca1-mediated-cholesterol-efflux-using-bodipy-cholesterol/) --- Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.