# Connective Tissue Growth Factor Research

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/connective-tissue-growth-factor-research/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the role of CCN proteins, particularly Connective Tissue Growth Factor (CTGF), in various signaling pathways such as TGF-ß and BMP, and their involvement in processes like angiogenesis, fibrosis, cell adhesion, regulation of gene expression, cancer progression, and wound healing. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t13223 |
| Works | 85 |

## Topic papers all

Showing 15 of 85.

- [Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma](https://scholariq.org/papers/avelumab-plus-axitinib-versus-sunitinib-for-advanced-renal-cell-carcinoma/)
- [Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma](https://scholariq.org/papers/pazopanib-versus-sunitinib-in-metastatic-renal-cell-carcinoma/)
- [Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma](https://scholariq.org/papers/lenvatinib-plus-pembrolizumab-or-everolimus-for-advanced-renal-cell-carcinoma/)
- [Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma](https://scholariq.org/papers/sunitinib-alone-or-after-nephrectomy-in-metastatic-renal-cell-carcinoma/)
- [A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling](https://scholariq.org/papers/a-novel-protein-encoded-by-a-circular-rna-circppp1r12a-promotes-tumor/)
- [TGF-β and fibrosis](https://scholariq.org/papers/tgf-and-fibrosis/)
- [Regulatory T cells promote myelin regeneration in the central nervous system](https://scholariq.org/papers/regulatory-t-cells-promote-myelin-regeneration-in-the-central-nervous-system/)
- [Expression of connective tissue growth factor in human renal fibrosis](https://scholariq.org/papers/expression-of-connective-tissue-growth-factor-in-human-renal-fibrosis/)
- [The good and the bad collagens of fibrosis – Their role in signaling and organ function](https://scholariq.org/papers/the-good-and-the-bad-collagens-of-fibrosis-their-role-in-signaling-and-organ/)
- [Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis](https://scholariq.org/papers/scar-associated-macrophages-are-a-major-source-of-hepatic-matrix/)
- [Phase II Randomized Trial Comparing Sequential First-Line Everolimus and Second-Line Sunitinib Versus First-Line Sunitinib and Second-Line Everolimus in Patients With Metastatic Renal Cell Carcinoma](https://scholariq.org/papers/phase-ii-randomized-trial-comparing-sequential-first-line-everolimus-and-second/)
- [Regulation of Connective Tissue Growth Factor Activity in Cultured Rat Mesangial Cells and Its Expression in Experimental Diabetic Glomerulosclerosis](https://scholariq.org/papers/regulation-of-connective-tissue-growth-factor-activity-in-cultured-rat-mesangial/)
- [Circular RNA circ-DONSON facilitates gastric cancer growth and invasion via NURF complex dependent activation of transcription factor SOX4](https://scholariq.org/papers/circular-rna-circ-donson-facilitates-gastric-cancer-growth-and-invasion-via-nurf/)
- [Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients](https://scholariq.org/papers/fresolimumab-treatment-decreases-biomarkers-and-improves-clinical-symptoms-in/)
- [Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study](https://scholariq.org/papers/longitudinal-change-in-collagen-degradation-biomarkers-in-idiopathic-pulmonary/)

## Topic primary papers

Showing 15 of 24.

- [TGF-β and fibrosis](https://scholariq.org/papers/tgf-and-fibrosis/)
- [Regulatory T cells promote myelin regeneration in the central nervous system](https://scholariq.org/papers/regulatory-t-cells-promote-myelin-regeneration-in-the-central-nervous-system/)
- [Expression of connective tissue growth factor in human renal fibrosis](https://scholariq.org/papers/expression-of-connective-tissue-growth-factor-in-human-renal-fibrosis/)
- [Regulation of Connective Tissue Growth Factor Activity in Cultured Rat Mesangial Cells and Its Expression in Experimental Diabetic Glomerulosclerosis](https://scholariq.org/papers/regulation-of-connective-tissue-growth-factor-activity-in-cultured-rat-mesangial/)
- [Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria](https://scholariq.org/papers/phase-1-study-of-anti-ctgf-monoclonal-antibody-in-patients-with-diabetes-and/)
- [Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal Fibrogenesis](https://scholariq.org/papers/connective-tissue-growth-factor-expressed-in-tubular-epithelium-plays-a-pivotal/)
- [The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells](https://scholariq.org/papers/the-differential-role-of-smad2-and-smad3-in-the-regulation-of-pro-fibrotic-tgf-1/)
- [Gene Therapy via Blockade of Monocyte Chemoattractant Protein-1 for Renal Fibrosis](https://scholariq.org/papers/gene-therapy-via-blockade-of-monocyte-chemoattractant-protein-1-for-renal/)
- [Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis](https://scholariq.org/papers/role-of-connective-tissue-growth-factor-in-fibronectin-expression-and/)
- [A Novel p53/microRNA‐22/Cyr61 Axis in Synovial Cells Regulates Inflammation in Rheumatoid Arthritis](https://scholariq.org/papers/a-novel-p53-microrna-22-cyr61-axis-in-synovial-cells-regulates-inflammation-in/)
- [Pentoxifylline Attenuates Tubulointerstitial Fibrosis by Blocking Smad3/4-Activated Transcription and Profibrogenic Effects of Connective Tissue Growth Factor](https://scholariq.org/papers/pentoxifylline-attenuates-tubulointerstitial-fibrosis-by-blocking-smad3-4/)
- [Role of connective tissue growth factor in profibrotic action of transforming growth factor-β: A potential target for preventing renal fibrosis](https://scholariq.org/papers/role-of-connective-tissue-growth-factor-in-profibrotic-action-of-transforming/)
- [Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review)](https://scholariq.org/papers/emerging-role-of-ccn-family-proteins-in-tumorigenesis-and-cancer-metastasis/)
- [Cyr61 Induces IL-6 Production by Fibroblast-like Synoviocytes Promoting Th17 Differentiation in Rheumatoid Arthritis](https://scholariq.org/papers/cyr61-induces-il-6-production-by-fibroblast-like-synoviocytes-promoting-th17/)
- [Connective tissue growth factor in human liver cirrhosis](https://scholariq.org/papers/connective-tissue-growth-factor-in-human-liver-cirrhosis/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.