# Developmental Biology and Gene Regulation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/developmental-biology-and-gene-regulation/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the Notch signaling pathway and its role in various aspects of development, including gene regulation, stem cell maintenance, embryonic development, and vertebrate origins. It also delves into the implications of Notch signaling in tumorigenesis and evolutionary biology. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10268 |
| Works | 59 |

## Topic papers all

Showing 15 of 59.

- [Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis](https://scholariq.org/papers/dll4-signalling-through-notch1-regulates-formation-of-tip-cells-during/)
- [Using FlyAtlas to identify better Drosophila melanogaster models of human disease](https://scholariq.org/papers/using-flyatlas-to-identify-better-drosophila-melanogaster-models-of-human/)
- [Notch2 Is Preferentially Expressed in Mature B Cells and Indispensable for Marginal Zone B Lineage Development](https://scholariq.org/papers/notch2-is-preferentially-expressed-in-mature-b-cells-and-indispensable-for/)
- [Nociceptive Neurons Protect Drosophila Larvae from Parasitoid Wasps](https://scholariq.org/papers/nociceptive-neurons-protect-drosophila-larvae-from-parasitoid-wasps/)
- [Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans](https://scholariq.org/papers/regenerative-proliferation-in-inner-ear-sensory-epithelia-from-adult-guinea-pigs/)
- [The Role of Maternal VegT in Establishing the Primary Germ Layers in Xenopus Embryos](https://scholariq.org/papers/the-role-of-maternal-vegt-in-establishing-the-primary-germ-layers-in-xenopus/)
- [Delta-like 4 is indispensable in thymic environment specific for T cell development](https://scholariq.org/papers/delta-like-4-is-indispensable-in-thymic-environment-specific-for-t-cell/)
- [Mouse Lefty2 and Zebrafish Antivin Are Feedback Inhibitors of Nodal Signaling during Vertebrate Gastrulation](https://scholariq.org/papers/mouse-lefty2-and-zebrafish-antivin-are-feedback-inhibitors-of-nodal-signaling/)
- [Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation](https://scholariq.org/papers/differential-effects-of-notch-ligands-delta-1-and-jagged-1-in-human-lymphoid/)
- [Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases](https://scholariq.org/papers/regulation-of-planar-cell-polarity-by-smurf-ubiquitin-ligases/)
- [Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2](https://scholariq.org/papers/recessive-robinow-syndrome-allelic-to-dominant-brachydactyly-type-b-is-caused-by/)
- [Twisted gastrulation is a conserved extracellular BMP antagonist](https://scholariq.org/papers/twisted-gastrulation-is-a-conserved-extracellular-bmp-antagonist/)
- [Candidate markers for stem and early progenitor cells, Musashi‐1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine](https://scholariq.org/papers/candidate-markers-for-stem-and-early-progenitor-cells-musashi-1-and-hes1-are/)
- [Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors](https://scholariq.org/papers/phase-i-study-of-ro4929097-a-gamma-secretase-inhibitor-of-notch-signaling-in/)
- [Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish](https://scholariq.org/papers/prickle-1-regulates-cell-movements-during-gastrulation-and-neuronal-migration-in/)

## Topic primary papers

Showing 15 of 27.

- [Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis](https://scholariq.org/papers/dll4-signalling-through-notch1-regulates-formation-of-tip-cells-during/)
- [Notch2 Is Preferentially Expressed in Mature B Cells and Indispensable for Marginal Zone B Lineage Development](https://scholariq.org/papers/notch2-is-preferentially-expressed-in-mature-b-cells-and-indispensable-for/)
- [The Role of Maternal VegT in Establishing the Primary Germ Layers in Xenopus Embryos](https://scholariq.org/papers/the-role-of-maternal-vegt-in-establishing-the-primary-germ-layers-in-xenopus/)
- [Mouse Lefty2 and Zebrafish Antivin Are Feedback Inhibitors of Nodal Signaling during Vertebrate Gastrulation](https://scholariq.org/papers/mouse-lefty2-and-zebrafish-antivin-are-feedback-inhibitors-of-nodal-signaling/)
- [Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation](https://scholariq.org/papers/differential-effects-of-notch-ligands-delta-1-and-jagged-1-in-human-lymphoid/)
- [Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases](https://scholariq.org/papers/regulation-of-planar-cell-polarity-by-smurf-ubiquitin-ligases/)
- [Twisted gastrulation is a conserved extracellular BMP antagonist](https://scholariq.org/papers/twisted-gastrulation-is-a-conserved-extracellular-bmp-antagonist/)
- [Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors](https://scholariq.org/papers/phase-i-study-of-ro4929097-a-gamma-secretase-inhibitor-of-notch-signaling-in/)
- [Mouse Jagged1 Physically Interacts with Notch2 and Other Notch Receptors](https://scholariq.org/papers/mouse-jagged1-physically-interacts-with-notch2-and-other-notch-receptors/)
- [The prickle-Related Gene in Vertebrates Is Essential for Gastrulation Cell Movements](https://scholariq.org/papers/the-prickle-related-gene-in-vertebrates-is-essential-for-gastrulation-cell/)
- [HERP, a New Primary Target of Notch Regulated by Ligand Binding](https://scholariq.org/papers/herp-a-new-primary-target-of-notch-regulated-by-ligand-binding/)
- [Maternal β-catenin establishes a ‘dorsal signal’ in early <i>Xenopus</i> embryos](https://scholariq.org/papers/maternal-catenin-establishes-a-dorsal-signal-in-early-i-xenopus-i-embryos/)
- [Patterning and post-patterning modes of evolutionary digit loss in mammals](https://scholariq.org/papers/patterning-and-post-patterning-modes-of-evolutionary-digit-loss-in-mammals/)
- [Initiation of Proximal-Distal Patterning in the Vertebrate Limb by Signals and Growth](https://scholariq.org/papers/initiation-of-proximal-distal-patterning-in-the-vertebrate-limb-by-signals-and/)
- [Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2](https://scholariq.org/papers/binding-of-delta1-jagged1-and-jagged2-to-notch2-rapidly-induces-cleavage-nuclear/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.