# Drug-Induced Adverse Reactions

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/drug-induced-adverse-reactions/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on hypersensitivity reactions to various drugs and medications, including the role of specific HLA genotypes such as HLA-B*5701, HLA-B*1502, and HLA-B*5801 in predicting severe cutaneous adverse reactions like Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. The cluster also covers topics related to drug-induced hypersensitivity syndrome (DIHS), delayed drug hypersensitivity reactions, and the use of genetic screening to prevent abacavir hypersensitivity reactions. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t11117 |
| Works | 193 |

## Topic papers all

Showing 15 of 193.

- [European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice](https://scholariq.org/papers/european-society-of-contact-dermatitis-guideline-for-diagnostic-patch-testing/)
- [Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin](https://scholariq.org/papers/cyclooxygenase-inhibitors-and-the-antiplatelet-effects-of-aspirin/)
- [A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions](https://scholariq.org/papers/a-comparison-of-measures-of-disproportionality-for-signal-detection-in/)
- [HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol](https://scholariq.org/papers/hla-b-5801-allele-as-a-genetic-marker-for-severe-cutaneous-adverse-reactions/)
- [Cytokine modulation of atopic dermatitis filaggrin skin expression](https://scholariq.org/papers/cytokine-modulation-of-atopic-dermatitis-filaggrin-skin-expression/)
- [Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology](https://scholariq.org/papers/anaphylaxis-guidelines-from-the-european-academy-of-allergy-and-clinical/)
- [Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study](https://scholariq.org/papers/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-an-original/)
- [Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials](https://scholariq.org/papers/treatment-related-adverse-events-of-pd-1-and-pd-l1-inhibitors-in-clinical-trials/)
- [Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan](https://scholariq.org/papers/carbamazepine-induced-toxic-effects-and-hla-b-1502-screening-in-taiwan/)
- [Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis](https://scholariq.org/papers/anaphylaxis-a-2020-practice-parameter-update-systematic-review-and-grading-of/)
- [Patiromer in Patients with Kidney Disease and Hyperkalemia Receiving RAAS Inhibitors](https://scholariq.org/papers/patiromer-in-patients-with-kidney-disease-and-hyperkalemia-receiving-raas/)
- [The diagnosis and management of anaphylaxis: An updated practice parameter](https://scholariq.org/papers/the-diagnosis-and-management-of-anaphylaxis-an-updated-practice-parameter/)
- [2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines](https://scholariq.org/papers/2015-update-of-the-evidence-base-world-allergy-organization-anaphylaxis/)
- [A randomized controlled study of peanut oral immunotherapy: Clinical desensitization and modulation of the allergic response](https://scholariq.org/papers/a-randomized-controlled-study-of-peanut-oral-immunotherapy-clinical/)
- [Guidelines for performing skin tests withdrugs in the investigation of cutaneous adverse drug reactions](https://scholariq.org/papers/guidelines-for-performing-skin-tests-withdrugs-in-the-investigation-of-cutaneous/)

## Topic primary papers

Showing 15 of 81.

- [HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol](https://scholariq.org/papers/hla-b-5801-allele-as-a-genetic-marker-for-severe-cutaneous-adverse-reactions/)
- [Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study](https://scholariq.org/papers/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-an-original/)
- [Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan](https://scholariq.org/papers/carbamazepine-induced-toxic-effects-and-hla-b-1502-screening-in-taiwan/)
- [Guidelines for performing skin tests withdrugs in the investigation of cutaneous adverse drug reactions](https://scholariq.org/papers/guidelines-for-performing-skin-tests-withdrugs-in-the-investigation-of-cutaneous/)
- [Drug Reaction With Eosinophilia and Systemic Symptoms](https://scholariq.org/papers/drug-reaction-with-eosinophilia-and-systemic-symptoms/)
- [Drug allergies documented in electronic health records of a large healthcare system](https://scholariq.org/papers/drug-allergies-documented-in-electronic-health-records-of-a-large-healthcare/)
- [Common Risk Allele in Aromatic Antiepileptic-Drug Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Han Chinese](https://scholariq.org/papers/common-risk-allele-in-aromatic-antiepileptic-drug-induced-stevens-johnson/)
- [Assessing the Diagnostic Properties of a Graded Oral Provocation Challenge for the Diagnosis of Immediate and Nonimmediate Reactions to Amoxicillin in Children](https://scholariq.org/papers/assessing-the-diagnostic-properties-of-a-graded-oral-provocation-challenge-for/)
- [Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study](https://scholariq.org/papers/prospective-genetic-screening-decreases-the-incidence-of-abacavir/)
- [Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions](https://scholariq.org/papers/genetic-variants-associated-with-phenytoin-related-severe-cutaneous-adverse/)
- [Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity](https://scholariq.org/papers/cost-effectiveness-analysis-of-hla-b-5701-genotyping-in-preventing-abacavir/)
- [Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System](https://scholariq.org/papers/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-an-interplay-among/)
- [Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions](https://scholariq.org/papers/randomized-controlled-trial-of-tnf-antagonist-in-ctl-mediated-severe-cutaneous/)
- [Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis – A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease](https://scholariq.org/papers/acute-and-chronic-ophthalmic-involvement-in-stevens-johnson-syndrome-toxic/)
- [Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy](https://scholariq.org/papers/efficacy-of-a-clinical-decision-rule-to-enable-direct-oral-challenge-in-patients/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.