# Drug Transport and Resistance Mechanisms

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/drug-transport-and-resistance-mechanisms-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 2,798,988 |
| Description | This cluster of papers explores the mechanisms of multidrug resistance in cancer, focusing on the role of ATP-dependent transporters, P-glycoprotein, bile acids, ABC transporters, and drug efflux pumps. It also delves into the involvement of nuclear receptors, metabolic regulation, and the impact on intestinal barrier function. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | https://openalex.org/T10570 |
| Works | 90,883 |

## Topic researchers

Showing 12 of 20.

- [Ahmedin Jemal](https://scholariq.org/researchers/ahmedin-jemal/)
- [Rebecca L. Siegel](https://scholariq.org/researchers/rebecca-l-siegel/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Bert Vogelstein](https://scholariq.org/researchers/bert-vogelstein/)
- [Richard A. Gibbs](https://scholariq.org/researchers/richard-a-gibbs/)
- [John Q. Trojanowski](https://scholariq.org/researchers/john-q-trojanowski/)
- [Todd R. Golub](https://scholariq.org/researchers/todd-r-golub/)
- [Matthew Meyerson](https://scholariq.org/researchers/matthew-meyerson/)
- [Michael Karin](https://scholariq.org/researchers/michael-karin/)
- [Mark I. McCarthy](https://scholariq.org/researchers/mark-i-mccarthy/)
- [George A. Mensah](https://scholariq.org/researchers/george-a-mensah/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.