# Eicosanoids and Hypertension Pharmacology

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/eicosanoids-and-hypertension-pharmacology/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the metabolism, function, and therapeutic implications of arachidonic acid derivatives, particularly epoxyeicosatrienoic acids (EETs), cytochrome P450 enzymes, and soluble epoxide hydrolase. The research covers their roles in cardiovascular function, inflammation, hypertension, and potential as therapeutic targets. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12910 |
| Works | 196 |

## Topic papers all

Showing 15 of 196.

- [Prostaglandins and Inflammation](https://scholariq.org/papers/prostaglandins-and-inflammation/)
- [Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease](https://scholariq.org/papers/fish-consumption-fish-oil-omega-3-fatty-acids-and-cardiovascular-disease/)
- [The explicit linear quadratic regulator for constrained systems](https://scholariq.org/papers/the-explicit-linear-quadratic-regulator-for-constrained-systems/)
- [Cytochrome P-450 Polymorphisms and Response to Clopidogrel](https://scholariq.org/papers/cytochrome-p-450-polymorphisms-and-response-to-clopidogrel/)
- [A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.](https://scholariq.org/papers/a-series-of-prostaglandin-f2-like-compounds-are-produced-in-vivo-in-humans-by-a/)
- [Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.](https://scholariq.org/papers/selectivity-of-nonsteroidal-antiinflammatory-drugs-as-inhibitors-of-constitutive/)
- [Polyunsaturated fatty acids and their metabolites in brain function and disease](https://scholariq.org/papers/polyunsaturated-fatty-acids-and-their-metabolites-in-brain-function-and-disease/)
- [The Coxibs, Selective Inhibitors of Cyclooxygenase-2](https://scholariq.org/papers/the-coxibs-selective-inhibitors-of-cyclooxygenase-2/)
- [Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2](https://scholariq.org/papers/systemic-biosynthesis-of-prostacyclin-by-cyclooxygenase-cox-2-the-human/)
- [Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.](https://scholariq.org/papers/nitric-oxide-synthase-modulates-angiogenesis-in-response-to-tissue-ischemia/)
- [Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors](https://scholariq.org/papers/inhibition-of-kg-dependent-histone-and-dna-demethylases-by-fumarate-and/)
- [n−3 Fatty acids from fish or fish-oil supplements, but not α-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review](https://scholariq.org/papers/n-3-fatty-acids-from-fish-or-fish-oil-supplements-but-not-linolenic-acid-benefit/)
- [Aspirin use and risk of fatal cancer.](https://scholariq.org/papers/aspirin-use-and-risk-of-fatal-cancer/)
- [Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.](https://scholariq.org/papers/cyclooxygenase-2-is-associated-with-the-macula-densa-of-rat-kidney-and-increases/)
- [Omega-6 Fatty Acids and Risk for Cardiovascular Disease](https://scholariq.org/papers/omega-6-fatty-acids-and-risk-for-cardiovascular-disease/)

## Topic primary papers

Showing 15 of 30.

- [A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.](https://scholariq.org/papers/a-series-of-prostaglandin-f2-like-compounds-are-produced-in-vivo-in-humans-by-a/)
- [Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase](https://scholariq.org/papers/cytochrome-p450-and-arachidonic-acid-bioactivation-molecular-and-functional/)
- [Epoxide hydrolases: their roles and interactions with lipid metabolism](https://scholariq.org/papers/epoxide-hydrolases-their-roles-and-interactions-with-lipid-metabolism/)
- [Soluble Epoxide Hydrolase Regulates Hydrolysis of Vasoactive Epoxyeicosatrienoic Acids](https://scholariq.org/papers/soluble-epoxide-hydrolase-regulates-hydrolysis-of-vasoactive-epoxyeicosatrienoic/)
- [Soluble epoxide hydrolase is a therapeutic target for acute inflammation](https://scholariq.org/papers/soluble-epoxide-hydrolase-is-a-therapeutic-target-for-acute-inflammation/)
- [The effects of hypertension on the cerebral circulation](https://scholariq.org/papers/the-effects-of-hypertension-on-the-cerebral-circulation/)
- [Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators](https://scholariq.org/papers/nitrated-fatty-acids-endogenous-anti-inflammatory-signaling-mediators/)
- [The differential effects of EPA and DHA on cardiovascular risk factors](https://scholariq.org/papers/the-differential-effects-of-epa-and-dha-on-cardiovascular-risk-factors/)
- [A pathogenic role of visceral fat beta 3-adrenoceptors in obesity.](https://scholariq.org/papers/a-pathogenic-role-of-visceral-fat-beta-3-adrenoceptors-in-obesity/)
- [Metabolism of the Lipid Peroxidation Product, 4-Hydroxy-trans-2-nonenal, in Isolated Perfused Rat Heart](https://scholariq.org/papers/metabolism-of-the-lipid-peroxidation-product-4-hydroxy-trans-2-nonenal-in/)
- [Atherosclerosis and oxidative stress](https://scholariq.org/papers/atherosclerosis-and-oxidative-stress/)
- [Vanadate-induced Expression of Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor through Phosphatidylinositol 3-Kinase/Akt Pathway and Reactive Oxygen Species](https://scholariq.org/papers/vanadate-induced-expression-of-hypoxia-inducible-factor-1-and-vascular/)
- [Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease](https://scholariq.org/papers/effects-of-arachidonic-acid-metabolites-on-cardiovascular-health-and-disease/)
- [Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450](https://scholariq.org/papers/metabolism-of-eicosapentaenoic-and-docosahexaenoic-acids-by-recombinant-human/)
- [Trimethylamine N-Oxide, Circulating Endothelial Progenitor Cells, and Endothelial Function in Patients with Stable Angina](https://scholariq.org/papers/trimethylamine-n-oxide-circulating-endothelial-progenitor-cells-and-endothelial/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.