# Enzyme function and inhibition

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/enzyme-function-and-inhibition/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of carbonic anhydrases in medicine and biotechnology, focusing on their inhibitors, activators, and their potential therapeutic applications in cancer therapy and CO2 capture. The papers cover a wide range of topics including tumor hypoxia, drug discovery, enzyme structure and function, and the use of carbonic anhydrases as targets for medicinal chemistry. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12412 |
| Works | 28 |

## Topic papers all

Showing 15 of 28.

- [Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents](https://scholariq.org/papers/design-of-specific-inhibitors-of-angiotensin-converting-enzyme-new-class-of/)
- [Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer](https://scholariq.org/papers/expression-of-hypoxia-inducible-cell-surface-transmembrane-carbonic-anhydrases/)
- [Review Article](https://scholariq.org/papers/review-article-2/)
- [Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX](https://scholariq.org/papers/crystal-structure-of-the-catalytic-domain-of-the-tumor-associated-human-carbonic/)
- [Free radical formation by antitumor quinones](https://scholariq.org/papers/free-radical-formation-by-antitumor-quinones/)
- [Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts](https://scholariq.org/papers/carbonic-anhydrase-ix-mn-ca-ix-analysis-of-stomach-complementary-dna-sequence/)
- [Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes](https://scholariq.org/papers/biochemical-characterization-of-ca-ix-one-of-the-most-active-carbonic-anhydrase/)
- [Carbonic anhydrase IX in oligodendroglial brain tumors](https://scholariq.org/papers/carbonic-anhydrase-ix-in-oligodendroglial-brain-tumors/)
- [Why Is Carbonic Anhydrase Essential to <i>Escherichia coli</i> ?](https://scholariq.org/papers/why-is-carbonic-anhydrase-essential-to-i-escherichia-coli-i/)
- [Carbonic anhydrase III protects cells from hydrogen peroxide‐induced apoptosis](https://scholariq.org/papers/carbonic-anhydrase-iii-protects-cells-from-hydrogen-peroxide-induced-apoptosis/)
- [Carbonic Anhydrase II Plays a Major Role in Osteoclast Differentiation and Bone Resorption by Effecting the Steady State Intracellular pH and Ca2+](https://scholariq.org/papers/carbonic-anhydrase-ii-plays-a-major-role-in-osteoclast-differentiation-and-bone/)
- [Antioxidant Properties of the Flavonoids Silybin and (+)-Cyanidanol-3: Comparison with Butylated Hydroxyanisole and Butylated Hydroxytoluene](https://scholariq.org/papers/antioxidant-properties-of-the-flavonoids-silybin-and-cyanidanol-3-comparison/)
- [Purification and molecular properties of mouse alcohol dehydrogenase isozymes](https://scholariq.org/papers/purification-and-molecular-properties-of-mouse-alcohol-dehydrogenase-isozymes/)
- [Consequences of Phosphate Imbalance](https://scholariq.org/papers/consequences-of-phosphate-imbalance/)
- [Purification, Molecular Properties and Ontogeny of Carbonic Anhydrase Isozymes. Evidence for A, B and C Isozymes in Avian and Mammalian Tissues](https://scholariq.org/papers/purification-molecular-properties-and-ontogeny-of-carbonic-anhydrase-isozymes/)

## Topic primary papers

- [Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer](https://scholariq.org/papers/expression-of-hypoxia-inducible-cell-surface-transmembrane-carbonic-anhydrases/)
- [Review Article](https://scholariq.org/papers/review-article-2/)
- [Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX](https://scholariq.org/papers/crystal-structure-of-the-catalytic-domain-of-the-tumor-associated-human-carbonic/)
- [Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts](https://scholariq.org/papers/carbonic-anhydrase-ix-mn-ca-ix-analysis-of-stomach-complementary-dna-sequence/)
- [Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes](https://scholariq.org/papers/biochemical-characterization-of-ca-ix-one-of-the-most-active-carbonic-anhydrase/)
- [Carbonic anhydrase IX in oligodendroglial brain tumors](https://scholariq.org/papers/carbonic-anhydrase-ix-in-oligodendroglial-brain-tumors/)
- [Why Is Carbonic Anhydrase Essential to <i>Escherichia coli</i> ?](https://scholariq.org/papers/why-is-carbonic-anhydrase-essential-to-i-escherichia-coli-i/)
- [Carbonic anhydrase III protects cells from hydrogen peroxide‐induced apoptosis](https://scholariq.org/papers/carbonic-anhydrase-iii-protects-cells-from-hydrogen-peroxide-induced-apoptosis/)
- [Carbonic Anhydrase II Plays a Major Role in Osteoclast Differentiation and Bone Resorption by Effecting the Steady State Intracellular pH and Ca2+](https://scholariq.org/papers/carbonic-anhydrase-ii-plays-a-major-role-in-osteoclast-differentiation-and-bone/)
- [Purification and molecular properties of mouse alcohol dehydrogenase isozymes](https://scholariq.org/papers/purification-and-molecular-properties-of-mouse-alcohol-dehydrogenase-isozymes/)
- [Purification, Molecular Properties and Ontogeny of Carbonic Anhydrase Isozymes. Evidence for A, B and C Isozymes in Avian and Mammalian Tissues](https://scholariq.org/papers/purification-molecular-properties-and-ontogeny-of-carbonic-anhydrase-isozymes/)
- [Acrylic copolymers as matrices for the immobilization of enzymes](https://scholariq.org/papers/acrylic-copolymers-as-matrices-for-the-immobilization-of-enzymes/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.