# Epigenetics and DNA Methylation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/epigenetics-and-dna-methylation/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the diverse mechanisms and functional implications of epigenetic modifications, including DNA methylation, histone modification, and chromatin remodeling. It delves into the role of these modifications in various biological processes such as cancer development, transgenerational inheritance, and environmental responses. Additionally, it discusses the potential applications of epigenetic therapy. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10269 |
| Works | 798 |

## Topic papers all

Showing 15 of 798.

- [Comprehensive genomic characterization defines human glioblastoma genes and core pathways](https://scholariq.org/papers/comprehensive-genomic-characterization-defines-human-glioblastoma-genes-and-core/)
- [A metagenome-wide association study of gut microbiota in type 2 diabetes](https://scholariq.org/papers/a-metagenome-wide-association-study-of-gut-microbiota-in-type-2-diabetes/)
- [Histone H3K27ac separates active from poised enhancers and predicts developmental state](https://scholariq.org/papers/histone-h3k27ac-separates-active-from-poised-enhancers-and-predicts/)
- [Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses](https://scholariq.org/papers/core-signaling-pathways-in-human-pancreatic-cancers-revealed-by-global-genomic/)
- [Genomic analyses identify molecular subtypes of pancreatic cancer](https://scholariq.org/papers/genomic-analyses-identify-molecular-subtypes-of-pancreatic-cancer/)
- [Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients](https://scholariq.org/papers/mutational-landscape-of-metastatic-cancer-revealed-from-prospective-clinical/)
- [Mapping and analysis of chromatin state dynamics in nine human cell types](https://scholariq.org/papers/mapping-and-analysis-of-chromatin-state-dynamics-in-nine-human-cell-types/)
- [Persistent epigenetic differences associated with prenatal exposure to famine in humans](https://scholariq.org/papers/persistent-epigenetic-differences-associated-with-prenatal-exposure-to-famine-in/)
- [Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene](https://scholariq.org/papers/identification-of-the-von-hippel-lindau-disease-tumor-suppressor-gene/)
- [Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels](https://scholariq.org/papers/genome-wide-association-analysis-identifies-loci-for-type-2-diabetes-and/)
- [Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer](https://scholariq.org/papers/cell-of-origin-patterns-dominate-the-molecular-classification-of-10-000-tumors/)
- [Whole genomes redefine the mutational landscape of pancreatic cancer](https://scholariq.org/papers/whole-genomes-redefine-the-mutational-landscape-of-pancreatic-cancer/)
- [International network of cancer genome projects](https://scholariq.org/papers/international-network-of-cancer-genome-projects/)
- [Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma](https://scholariq.org/papers/identification-of-a-cpg-island-methylator-phenotype-that-defines-a-distinct/)
- [Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma](https://scholariq.org/papers/molecular-profiling-reveals-biologically-discrete-subsets-and-pathways-of/)

## Topic primary papers

Showing 15 of 257.

- [Persistent epigenetic differences associated with prenatal exposure to famine in humans](https://scholariq.org/papers/persistent-epigenetic-differences-associated-with-prenatal-exposure-to-famine-in/)
- [Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma](https://scholariq.org/papers/identification-of-a-cpg-island-methylator-phenotype-that-defines-a-distinct/)
- [Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression](https://scholariq.org/papers/metabolomic-profiles-delineate-potential-role-for-sarcosine-in-prostate-cancer/)
- [5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers](https://scholariq.org/papers/5-cpg-island-methylation-is-associated-with-transcriptional-silencing-of-the/)
- [Functional genomics reveal that the serine synthesis pathway is essential in breast cancer](https://scholariq.org/papers/functional-genomics-reveal-that-the-serine-synthesis-pathway-is-essential-in/)
- [Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin](https://scholariq.org/papers/somatic-mutations-altering-ezh2-tyr641-in-follicular-and-diffuse-large-b-cell/)
- [DNA methylation age of blood predicts all-cause mortality in later life](https://scholariq.org/papers/dna-methylation-age-of-blood-predicts-all-cause-mortality-in-later-life/)
- [Aberrant CpG-island methylation has non-random and tumour-type–specific patterns](https://scholariq.org/papers/aberrant-cpg-island-methylation-has-non-random-and-tumour-type-specific-patterns/)
- [Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.](https://scholariq.org/papers/inactivation-of-the-cdkn2-p16-mts1-gene-is-frequently-associated-with-aberrant/)
- [Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1](https://scholariq.org/papers/erythroid-differentiation-in-chimaeric-mice-blocked-by-a-targeted-mutation-in/)
- [DNA methylation-based measures of biological age: meta-analysis predicting time to death](https://scholariq.org/papers/dna-methylation-based-measures-of-biological-age-meta-analysis-predicting-time/)
- [Somatic mutant clones colonize the human esophagus with age](https://scholariq.org/papers/somatic-mutant-clones-colonize-the-human-esophagus-with-age/)
- [DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific](https://scholariq.org/papers/dna-methylation-differences-after-exposure-to-prenatal-famine-are-common-and/)
- [Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors](https://scholariq.org/papers/inhibition-of-kg-dependent-histone-and-dna-demethylases-by-fumarate-and/)
- [Epigenetic Signatures of Cigarette Smoking](https://scholariq.org/papers/epigenetic-signatures-of-cigarette-smoking/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.