# Fibroblast Growth Factor Research
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/fibroblast-growth-factor-research/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the Fibroblast Growth Factor (FGF) signaling pathway, covering its role in development, metabolism, cancer, and therapy. It explores the involvement of FGF21, FGF receptors, and PPARa in various physiological processes such as hepatic lipid metabolism, insulin sensitivity, and bone development. Additionally, it discusses the potential therapeutic implications of targeting FGF signaling in conditions like obesity and cancer. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12287 |
| Works | 157 |
## Topic papers all
Showing 15 of 157.
- [The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis](https://scholariq.org/papers/the-tumour-suppressor-protein-vhl-targets-hypoxia-inducible-factors-for-oxygen/)
- [Overall Survival with Osimertinib in Untreated, EGFR -Mutated Advanced NSCLC](https://scholariq.org/papers/overall-survival-with-osimertinib-in-untreated-i-egfr-i-mutated-advanced-nsclc/)
- [FGF23 induces left ventricular hypertrophy](https://scholariq.org/papers/fgf23-induces-left-ventricular-hypertrophy/)
- [Sotorasib for Lung Cancers with KRAS p.G12C Mutation](https://scholariq.org/papers/sotorasib-for-lung-cancers-with-i-kras-i-p-g12c-mutation/)
- [Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23](https://scholariq.org/papers/autosomal-dominant-hypophosphataemic-rickets-is-associated-with-mutations-in/)
- [Hyaluronan as an Immune Regulator in Human Diseases](https://scholariq.org/papers/hyaluronan-as-an-immune-regulator-in-human-diseases/)
- [Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells](https://scholariq.org/papers/nitric-oxide-plays-a-critical-role-in-suppression-of-t-cell-proliferation-by/)
- [Hyaluronan in Tissue Injury and Repair](https://scholariq.org/papers/hyaluronan-in-tissue-injury-and-repair/)
- [Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease](https://scholariq.org/papers/fibroblast-growth-factor-23-and-left-ventricular-hypertrophy-in-chronic-kidney/)
- [VHL, the story of a tumour suppressor gene](https://scholariq.org/papers/vhl-the-story-of-a-tumour-suppressor-gene/)
- [Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma](https://scholariq.org/papers/transforming-fusions-of-i-fgfr-i-and-i-tacc-i-genes-in-human-glioblastoma/)
- [Brivanib Versus Sorafenib As First-Line Therapy in Patients With Unresectable, Advanced Hepatocellular Carcinoma: Results From the Randomized Phase III BRISK-FL Study](https://scholariq.org/papers/brivanib-versus-sorafenib-as-first-line-therapy-in-patients-with-unresectable/)
- [The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21](https://scholariq.org/papers/the-metabolic-state-of-diabetic-monkeys-is-regulated-by-fibroblast-growth-factor/)
- [Rociletinib in EGFR-Mutated Non–Small-Cell Lung Cancer](https://scholariq.org/papers/rociletinib-in-i-egfr-i-mutated-non-small-cell-lung-cancer/)
- [Purification and Complementary DNA Cloning of a Receptor for Basic Fibroblast Growth Factor](https://scholariq.org/papers/purification-and-complementary-dna-cloning-of-a-receptor-for-basic-fibroblast/)
## Topic primary papers
Showing 15 of 54.
- [Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma](https://scholariq.org/papers/transforming-fusions-of-i-fgfr-i-and-i-tacc-i-genes-in-human-glioblastoma/)
- [The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21](https://scholariq.org/papers/the-metabolic-state-of-diabetic-monkeys-is-regulated-by-fibroblast-growth-factor/)
- [Purification and Complementary DNA Cloning of a Receptor for Basic Fibroblast Growth Factor](https://scholariq.org/papers/purification-and-complementary-dna-cloning-of-a-receptor-for-basic-fibroblast/)
- [Pharmacological Treatment of Coronary Artery Disease With Recombinant Fibroblast Growth Factor-2](https://scholariq.org/papers/pharmacological-treatment-of-coronary-artery-disease-with-recombinant-fibroblast/)
- [Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy](https://scholariq.org/papers/activation-of-cardiac-fibroblast-growth-factor-receptor-4-causes-left/)
- [Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation](https://scholariq.org/papers/disruption-of-the-fibroblast-growth-factor-2-gene-results-in-decreased-bone-mass/)
- [Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study](https://scholariq.org/papers/evaluation-of-bgj398-a-fibroblast-growth-factor-receptor-1-3-kinase-inhibitor-in/)
- [The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine](https://scholariq.org/papers/the-adverse-metabolic-effects-of-branched-chain-amino-acids-are-mediated-by/)
- [FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor](https://scholariq.org/papers/fgfr-genetic-alterations-predict-for-sensitivity-to-nvp-bgj398-a-selective-pan/)
- [Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms](https://scholariq.org/papers/three-subtypes-of-lung-cancer-fibroblasts-define-distinct-therapeutic-paradigms/)
- [FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547](https://scholariq.org/papers/i-fgfr2-i-gene-amplification-in-gastric-cancer-predicts-sensitivity-to-the/)
- [Intracoronary basic fibroblast growth factor (FGF-2) in patients with severe ischemic heart disease: results of a Phase I open-label dose escalation study](https://scholariq.org/papers/intracoronary-basic-fibroblast-growth-factor-fgf-2-in-patients-with-severe/)
- [HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells](https://scholariq.org/papers/hif1-is-required-for-survival-maintenance-of-chronic-myeloid-leukemia-stem-cells/)
- [Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors](https://scholariq.org/papers/development-of-covalent-inhibitors-that-can-overcome-resistance-to-first/)
- [Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation](https://scholariq.org/papers/fibroblast-growth-factor-receptor-signaling-is-essential-for-lens-fiber-cell/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.