# FOXO transcription factor regulation
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/foxo-transcription-factor-regulation/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the regulation and diverse functions of FoxO transcription factors, including their roles in cell cycle regulation, response to oxidative stress, metabolism, apoptosis, cancer development and therapy, aging, DNA repair, and insulin signaling. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12835 |
| Works | 82 |
## Topic papers all
Showing 15 of 82.
- [Integrated genomic analyses of ovarian carcinoma](https://scholariq.org/papers/integrated-genomic-analyses-of-ovarian-carcinoma/)
- [The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer](https://scholariq.org/papers/the-role-of-tumoral-foxp3-on-cell-proliferation-migration-and-invasion-in/)
- [Association of reactive oxygen species levels and radioresistance in cancer stem cells](https://scholariq.org/papers/association-of-reactive-oxygen-species-levels-and-radioresistance-in-cancer-stem/)
- [Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition](https://scholariq.org/papers/circulating-breast-tumor-cells-exhibit-dynamic-changes-in-epithelial-and/)
- [Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)](https://scholariq.org/papers/mutations-in-the-hepatocyte-nuclear-factor-1-gene-in-maturity-onset-diabetes-of/)
- [Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells](https://scholariq.org/papers/downregulation-of-mirna-200c-links-breast-cancer-stem-cells-with-normal-stem/)
- [Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance](https://scholariq.org/papers/i-rb1-i-and-i-trp53-i-cooperate-to-suppress-prostate-cancer-lineage-plasticity/)
- [The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis](https://scholariq.org/papers/the-androgen-receptor-cistrome-is-extensively-reprogrammed-in-human-prostate/)
- [The regulation of FOXO1 and its role in disease progression](https://scholariq.org/papers/the-regulation-of-foxo1-and-its-role-in-disease-progression/)
- [Dclk1 distinguishes between tumor and normal stem cells in the intestine](https://scholariq.org/papers/dclk1-distinguishes-between-tumor-and-normal-stem-cells-in-the-intestine/)
- [The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection](https://scholariq.org/papers/the-transcription-factor-foxo1-sustains-expression-of-the-inhibitory-receptor-pd/)
- [Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance](https://scholariq.org/papers/acquisition-of-epithelial-mesenchymal-transition-and-cancer-stem-cell-phenotypes/)
- [The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling](https://scholariq.org/papers/the-foxo3a-transcription-factor-regulates-cardiac-myocyte-size-downstream-of-akt/)
- [Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis](https://scholariq.org/papers/foxo3-activity-promoted-by-non-coding-effects-of-circular-rna-and-foxo3/)
- [Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study](https://scholariq.org/papers/association-of-the-i-foxo3a-i-locus-with-extreme-longevity-in-a-southern-italian/)
## Topic primary papers
Showing 15 of 37.
- [The regulation of FOXO1 and its role in disease progression](https://scholariq.org/papers/the-regulation-of-foxo1-and-its-role-in-disease-progression/)
- [The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection](https://scholariq.org/papers/the-transcription-factor-foxo1-sustains-expression-of-the-inhibitory-receptor-pd/)
- [The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling](https://scholariq.org/papers/the-foxo3a-transcription-factor-regulates-cardiac-myocyte-size-downstream-of-akt/)
- [Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study](https://scholariq.org/papers/association-of-the-i-foxo3a-i-locus-with-extreme-longevity-in-a-southern-italian/)
- [Loss of FOXA1/2 Is Essential for the Epithelial-to-Mesenchymal Transition in Pancreatic Cancer](https://scholariq.org/papers/loss-of-foxa1-2-is-essential-for-the-epithelial-to-mesenchymal-transition-in/)
- [AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias](https://scholariq.org/papers/akt-foxo-signaling-enforces-reversible-differentiation-blockade-in-myeloid/)
- [Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling](https://scholariq.org/papers/colorectal-cancer-cell-derived-ccl20-recruits-regulatory-t-cells-to-promote/)
- [Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal Cells](https://scholariq.org/papers/transcriptional-cross-talk-between-the-forkhead-transcription-factor-forkhead/)
- [Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis](https://scholariq.org/papers/increased-expression-and-activity-of-the-transcription-factor-foxo1-in/)
- [Foxf1 knockdown promotes BMSC osteogenesis in part by activating the Wnt/β-catenin signalling pathway and prevents ovariectomy-induced bone loss](https://scholariq.org/papers/foxf1-knockdown-promotes-bmsc-osteogenesis-in-part-by-activating-the-wnt-catenin/)
- [Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress](https://scholariq.org/papers/linking-alzheimer-s-disease-to-insulin-resistance-the-foxo-response-to-oxidative/)
- [Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism](https://scholariq.org/papers/yin-yang-1-suppresses-invasion-and-metastasis-of-pancreatic-ductal/)
- [Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates](https://scholariq.org/papers/selenium-sensitizes-mcf-7-breast-cancer-cells-to-doxorubicin-induced-apoptosis/)
- [Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim](https://scholariq.org/papers/stem-cell-factor-promotes-mast-cell-survival-via-inactivation-of-foxo3a-mediated/)
- [FOXF2 suppresses the FOXC2-mediated epithelial–mesenchymal transition and multidrug resistance of basal-like breast cancer](https://scholariq.org/papers/foxf2-suppresses-the-foxc2-mediated-epithelial-mesenchymal-transition-and/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.