# Galectins and Cancer Biology
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/galectins-and-cancer-biology/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the diverse roles of galectins in immune regulation, inflammation, cancer, macrophage activation, T cell dysfunction, fibrosis, angiogenesis, heart failure, and autoimmunity. Galectins are implicated in modulating various aspects of immune responses and have potential implications for therapeutic interventions in a range of diseases. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t12387 |
| Works | 183 |
## Topic papers all
Showing 15 of 183.
- [Interleukin-1 polymorphisms associated with increased risk of gastric cancer](https://scholariq.org/papers/interleukin-1-polymorphisms-associated-with-increased-risk-of-gastric-cancer/)
- [Protein Tyrosine Phosphatases in the Human Genome](https://scholariq.org/papers/protein-tyrosine-phosphatases-in-the-human-genome/)
- [Reactivity of a monoclonal antibody with human ovarian carcinoma.](https://scholariq.org/papers/reactivity-of-a-monoclonal-antibody-with-human-ovarian-carcinoma/)
- [Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints](https://scholariq.org/papers/adaptive-resistance-to-therapeutic-pd-1-blockade-is-associated-with-upregulation/)
- [A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis](https://scholariq.org/papers/a-missense-single-nucleotide-polymorphism-in-a-gene-encoding-a-protein-tyrosine/)
- [Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo](https://scholariq.org/papers/blockade-of-interleukin-6-trans-signaling-suppresses-t-cell-resistance-against/)
- [Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus](https://scholariq.org/papers/genome-wide-association-study-in-a-chinese-han-population-identifies-nine-new/)
- [IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis](https://scholariq.org/papers/il-13-signaling-through-the-il-13-2-receptor-is-involved-in-induction-of-tgf-1/)
- [T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ](https://scholariq.org/papers/t-cell-adhesion-induced-by-proteoglycan-immobilized-cytokine-mip-l/)
- [Megalin and cubilin: multifunctional endocytic receptors](https://scholariq.org/papers/megalin-and-cubilin-multifunctional-endocytic-receptors/)
- [Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals](https://scholariq.org/papers/genomic-and-drug-target-evaluation-of-90-cardiovascular-proteins-in-30-931/)
- [The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm](https://scholariq.org/papers/the-same-sequence-variant-on-9p21-associates-with-myocardial-infarction/)
- [Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes.](https://scholariq.org/papers/cytotoxic-t-lymphocyte-granules-are-secretory-lysosomes-containing-both-perforin/)
- [Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus.](https://scholariq.org/papers/nucleosome-a-major-immunogen-for-pathogenic-autoantibody-inducing-t-cells-of/)
- [The importance of natural IgM: scavenger, protector and regulator](https://scholariq.org/papers/the-importance-of-natural-igm-scavenger-protector-and-regulator/)
## Topic primary papers
Showing 15 of 41.
- [Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals](https://scholariq.org/papers/genomic-and-drug-target-evaluation-of-90-cardiovascular-proteins-in-30-931/)
- [Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas](https://scholariq.org/papers/combination-therapy-with-anti-pd-1-anti-tim-3-and-focal-radiation-results-in/)
- [Genetic and Pharmacological Inhibition of Galectin-3 Prevents Cardiac Remodeling by Interfering With Myocardial Fibrogenesis](https://scholariq.org/papers/genetic-and-pharmacological-inhibition-of-galectin-3-prevents-cardiac-remodeling/)
- [Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis](https://scholariq.org/papers/galectin-3-mediates-aldosterone-induced-vascular-fibrosis/)
- [Identification and Characterization of Galectin-9, a Novel β-Galactoside-binding Mammalian Lectin](https://scholariq.org/papers/identification-and-characterization-of-galectin-9-a-novel-galactoside-binding/)
- [Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro](https://scholariq.org/papers/functional-variation-in-lgals2-confers-risk-of-myocardial-infarction-and/)
- [Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells](https://scholariq.org/papers/galectin-1-a-novel-ligand-of-neuropilin-1-activates-vegfr-2-signaling-and/)
- [Galectin-3 in autoimmunity and autoimmune diseases](https://scholariq.org/papers/galectin-3-in-autoimmunity-and-autoimmune-diseases/)
- [Structural Basis for the Recognition of Carbohydrates by Human Galectin-7,](https://scholariq.org/papers/structural-basis-for-the-recognition-of-carbohydrates-by-human-galectin-7-sup/)
- [Thymosin Alpha 1 Reduces the Mortality of Severe Coronavirus Disease 2019 by Restoration of Lymphocytopenia and Reversion of Exhausted T Cells](https://scholariq.org/papers/thymosin-alpha-1-reduces-the-mortality-of-severe-coronavirus-disease-2019-by/)
- [High expression of Galectin‐1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer](https://scholariq.org/papers/high-expression-of-i-galectin-1-i-in-pancreatic-stellate-cells-plays-a-role-in/)
- [Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease](https://scholariq.org/papers/galectin-3-promotes-a-oligomerization-and-a-toxicity-in-a-mouse-model-of/)
- [The relationship between serum galectin-3 and serum markers of cardiac extracellular matrix turnover in heart failure patients](https://scholariq.org/papers/the-relationship-between-serum-galectin-3-and-serum-markers-of-cardiac/)
- [Modified Citrus Pectin Reduces Galectin-3 Expression and Disease Severity in Experimental Acute Kidney Injury](https://scholariq.org/papers/modified-citrus-pectin-reduces-galectin-3-expression-and-disease-severity-in/)
- [The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart ‘OMics’ in AGEing (HOMAGE) randomized clinical trial](https://scholariq.org/papers/the-effect-of-spironolactone-on-cardiovascular-function-and-markers-of-fibrosis/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.