# GDF15 and Related Biomarkers

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/gdf15-and-related-biomarkers/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of growth factors, particularly Growth-Differentiation Factor-15 (GDF-15) and Macrophage Inhibitory Cytokine-1 (MIC-1), in various physiological and pathological processes such as cardiovascular disease, obesity, metabolic homeostasis, neuroprotection, and inflammation. The papers also investigate the potential of these factors as biomarkers for different health conditions. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t13452 |
| Works | 69 |

## Topic papers all

Showing 15 of 69.

- [Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure](https://scholariq.org/papers/elevated-circulating-levels-of-tumor-necrosis-factor-in-severe-chronic-heart/)
- [Biomarkers in Heart Failure](https://scholariq.org/papers/biomarkers-in-heart-failure/)
- [Early Increases in Multiple Biomarkers Predict Subsequent Cardiotoxicity in Patients With Breast Cancer Treated With Doxorubicin, Taxanes, and Trastuzumab](https://scholariq.org/papers/early-increases-in-multiple-biomarkers-predict-subsequent-cardiotoxicity-in/)
- [Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways](https://scholariq.org/papers/ferroptosis-is-essential-for-diabetic-cardiomyopathy-and-is-prevented-by/)
- [The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study](https://scholariq.org/papers/the-novel-biomarker-based-abc-age-biomarkers-clinical-history-bleeding-risk/)
- [The Application of Ferroptosis in Diseases](https://scholariq.org/papers/the-application-of-ferroptosis-in-diseases/)
- [Atlas of the plasma proteome in health and disease in 53,026 adults](https://scholariq.org/papers/atlas-of-the-plasma-proteome-in-health-and-disease-in-53-026-adults/)
- [Cancer Cachexia: Its Mechanism and Clinical Significance](https://scholariq.org/papers/cancer-cachexia-its-mechanism-and-clinical-significance/)
- [Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation](https://scholariq.org/papers/adipokines-hepatokines-and-myokines-focus-on-their-role-and-molecular-mechanisms/)
- [Identification of potential saliva and tear biomarkers in primary Sjögren’s syndrome, utilising the extraction of extracellular vesicles and proteomics analysis](https://scholariq.org/papers/identification-of-potential-saliva-and-tear-biomarkers-in-primary-sjogren-s/)
- [Dietary isoflavones in the prevention of cardiovascular disease – A molecular perspective](https://scholariq.org/papers/dietary-isoflavones-in-the-prevention-of-cardiovascular-disease-a-molecular/)
- [Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis](https://scholariq.org/papers/increased-expression-and-activity-of-the-transcription-factor-foxo1-in/)
- [Inflammation markers and risk of developing hypertension: a meta-analysis of cohort studies](https://scholariq.org/papers/inflammation-markers-and-risk-of-developing-hypertension-a-meta-analysis-of/)
- [NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development](https://scholariq.org/papers/nf-b-regulates-gdf-15-to-suppress-macrophage-surveillance-during-early-tumor/)
- [Growth Differentiation Factor 15 in Heart Failure with Preserved vs. Reduced Ejection Fraction](https://scholariq.org/papers/growth-differentiation-factor-15-in-heart-failure-with-preserved-vs-reduced/)

## Topic primary papers

Showing 15 of 19.

- [Biomarkers in Heart Failure](https://scholariq.org/papers/biomarkers-in-heart-failure/)
- [The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study](https://scholariq.org/papers/the-novel-biomarker-based-abc-age-biomarkers-clinical-history-bleeding-risk/)
- [Atlas of the plasma proteome in health and disease in 53,026 adults](https://scholariq.org/papers/atlas-of-the-plasma-proteome-in-health-and-disease-in-53-026-adults/)
- [NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development](https://scholariq.org/papers/nf-b-regulates-gdf-15-to-suppress-macrophage-surveillance-during-early-tumor/)
- [Growth Differentiation Factor 15 in Heart Failure with Preserved vs. Reduced Ejection Fraction](https://scholariq.org/papers/growth-differentiation-factor-15-in-heart-failure-with-preserved-vs-reduced/)
- [Acute Myeloid Leukemia-Associated <i>Mkl1 (Mrtf-a)</i> Is a Key Regulator of Mammary Gland Function](https://scholariq.org/papers/acute-myeloid-leukemia-associated-i-mkl1-mrtf-a-i-is-a-key-regulator-of-mammary/)
- [Expression of growth differentiation factor‐15/ macrophage inhibitory cytokine‐1 (GDF‐15/MIC‐1) in the perinatal, adult, and injured rat brain](https://scholariq.org/papers/expression-of-growth-differentiation-factor-15-macrophage-inhibitory-cytokine-1/)
- [Plasma proteomic profiles predict individual future health risk](https://scholariq.org/papers/plasma-proteomic-profiles-predict-individual-future-health-risk/)
- [Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK–RhoA signaling pathway](https://scholariq.org/papers/overexpression-of-macrophage-inhibitory-cytokine-1-induces-metastasis-of-human/)
- [<i>LINC00116</i> codes for a mitochondrial peptide linking respiration and lipid metabolism](https://scholariq.org/papers/i-linc00116-i-codes-for-a-mitochondrial-peptide-linking-respiration-and-lipid/)
- [Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma](https://scholariq.org/papers/macrophage-inhibitory-cytokine-1-mic-1-gdf15-as-a-novel-diagnostic-serum/)
- [GDF 15 - A Novel Biomarker in the Offing for Heart Failure](https://scholariq.org/papers/gdf-15-a-novel-biomarker-in-the-offing-for-heart-failure/)
- [GDF15 is a potential predictive biomarker for TPF induction chemotherapy and promotes tumorigenesis and progression in oral squamous cell carcinoma](https://scholariq.org/papers/gdf15-is-a-potential-predictive-biomarker-for-tpf-induction-chemotherapy-and/)
- [Nrf2 epigenetic derepression induced by running exercise protects against osteoporosis](https://scholariq.org/papers/nrf2-epigenetic-derepression-induced-by-running-exercise-protects-against/)
- [Colivelin Rescues Ischemic Neuron and Axons Involving JAK/STAT3 Signaling Pathway](https://scholariq.org/papers/colivelin-rescues-ischemic-neuron-and-axons-involving-jak-stat3-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.