# Genetic Neurodegenerative Diseases

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/genetic-neurodegenerative-diseases-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 1,711,055 |
| Description | This cluster of papers explores the molecular mechanisms underlying neurodegenerative diseases such as Huntington's disease, myotonic dystrophy, and ataxias. It focuses on protein aggregation, polyglutamine toxicity, mitochondrial dysfunction, RNA-mediated disorders, chaperone function, gene expression dysregulation, and the role of trinucleotide repeats in neuronal degeneration. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | https://openalex.org/T10949 |
| Works | 86,707 |

## Topic institutions

Showing 12 of 20.

- [Massachusetts General Hospital](https://scholariq.org/institutions/massachusetts-general-hospital/)
- [Harvard University](https://scholariq.org/institutions/harvard-university/)
- [Johns Hopkins University](https://scholariq.org/institutions/johns-hopkins-university/)
- [Johns Hopkins Medicine](https://scholariq.org/institutions/johns-hopkins-medicine/)
- [Inserm](https://scholariq.org/institutions/inserm/)
- [Howard Hughes Medical Institute](https://scholariq.org/institutions/howard-hughes-medical-institute/)
- [University of California, Los Angeles](https://scholariq.org/institutions/university-of-california-los-angeles/)
- [Massachusetts Institute of Technology](https://scholariq.org/institutions/massachusetts-institute-of-technology/)
- [Sorbonne Université](https://scholariq.org/institutions/sorbonne-universite/)
- [Emory University](https://scholariq.org/institutions/emory-university/)
- [Stanford University](https://scholariq.org/institutions/stanford-university/)
- [Pitié-Salpêtrière Hospital](https://scholariq.org/institutions/pitie-salpetriere-hospital/)

## Topic researchers

Showing 12 of 20.

- [Eric S. Lander](https://scholariq.org/researchers/eric-s-lander/)
- [Richard Durbin](https://scholariq.org/researchers/richard-durbin/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Stacey Gabriel](https://scholariq.org/researchers/stacey-gabriel/)
- [Peer Bork](https://scholariq.org/researchers/peer-bork/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)
- [Valery L. Feigin](https://scholariq.org/researchers/valery-l-feigin/)
- [Karl Friston](https://scholariq.org/researchers/karl-friston/)
- [Matthias Mann](https://scholariq.org/researchers/matthias-mann/)
- [Richard A. Gibbs](https://scholariq.org/researchers/richard-a-gibbs/)
- [John Q. Trojanowski](https://scholariq.org/researchers/john-q-trojanowski/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.