# Genetic Neurodegenerative Diseases

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/genetic-neurodegenerative-diseases/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the molecular mechanisms underlying neurodegenerative diseases such as Huntington's disease, myotonic dystrophy, and ataxias. It focuses on protein aggregation, polyglutamine toxicity, mitochondrial dysfunction, RNA-mediated disorders, chaperone function, gene expression dysregulation, and the role of trinucleotide repeats in neuronal degeneration. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t10949 |
| Works | 311 |

## Topic papers all

Showing 15 of 311.

- [The functional anatomy of basal ganglia disorders](https://scholariq.org/papers/the-functional-anatomy-of-basal-ganglia-disorders/)
- [AGEING AND PARKINSON'S DISEASE: SUBSTANTIA NIGRA REGIONAL SELECTIVITY](https://scholariq.org/papers/ageing-and-parkinson-s-disease-substantia-nigra-regional-selectivity/)
- [Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home](https://scholariq.org/papers/multiple-wearable-sensors-in-parkinson-and-huntington-disease-individuals-a/)
- [Second consensus statement on the diagnosis of multiple system atrophy](https://scholariq.org/papers/second-consensus-statement-on-the-diagnosis-of-multiple-system-atrophy/)
- [A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.](https://scholariq.org/papers/a-novel-gene-containing-a-trinucleotide-repeat-that-is-expanded-and-unstable-on/)
- [Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy](https://scholariq.org/papers/foxo-transcription-factors-induce-the-atrophy-related-ubiquitin-ligase-atrogin-1/)
- [Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome)](https://scholariq.org/papers/clinical-research-criteria-for-the-diagnosis-of-progressive-supranuclear-palsy/)
- [Amyotrophic lateral sclerosis](https://scholariq.org/papers/amyotrophic-lateral-sclerosis/)
- [Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease](https://scholariq.org/papers/cloning-of-the-gene-containing-mutations-that-cause-park8-linked-parkinson-s/)
- [Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria](https://scholariq.org/papers/clinical-diagnosis-of-progressive-supranuclear-palsy-the-movement-disorder/)
- [A polymorphic DNA marker genetically linked to Huntington's disease](https://scholariq.org/papers/a-polymorphic-dna-marker-genetically-linked-to-huntington-s-disease/)
- [Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4](https://scholariq.org/papers/familial-hemiplegic-migraine-and-episodic-ataxia-type-2-are-caused-by-mutations/)
- [Parkinson's disease](https://scholariq.org/papers/parkinson-s-disease-2/)
- [High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease](https://scholariq.org/papers/high-levels-of-mitochondrial-dna-deletions-in-substantia-nigra-neurons-in-aging/)
- [Consensus statement on the diagnosis of multiple system atrophy](https://scholariq.org/papers/consensus-statement-on-the-diagnosis-of-multiple-system-atrophy/)

## Topic primary papers

Showing 15 of 120.

- [Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home](https://scholariq.org/papers/multiple-wearable-sensors-in-parkinson-and-huntington-disease-individuals-a/)
- [A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.](https://scholariq.org/papers/a-novel-gene-containing-a-trinucleotide-repeat-that-is-expanded-and-unstable-on/)
- [A polymorphic DNA marker genetically linked to Huntington's disease](https://scholariq.org/papers/a-polymorphic-dna-marker-genetically-linked-to-huntington-s-disease/)
- [Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4](https://scholariq.org/papers/familial-hemiplegic-migraine-and-episodic-ataxia-type-2-are-caused-by-mutations/)
- [High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease](https://scholariq.org/papers/high-levels-of-mitochondrial-dna-deletions-in-substantia-nigra-neurons-in-aging/)
- [Consensus statement on the diagnosis of multiple system atrophy](https://scholariq.org/papers/consensus-statement-on-the-diagnosis-of-multiple-system-atrophy/)
- [Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila](https://scholariq.org/papers/histone-deacetylase-inhibitors-arrest-polyglutamine-dependent-neurodegeneration/)
- [Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines](https://scholariq.org/papers/early-mitochondrial-calcium-defects-in-huntington-s-disease-are-a-direct-effect/)
- [Differential loss of striatal projection neurons in Huntington disease.](https://scholariq.org/papers/differential-loss-of-striatal-projection-neurons-in-huntington-disease/)
- [Nuclear and Neuropil Aggregates in Huntington’s Disease: Relationship to Neuropathology](https://scholariq.org/papers/nuclear-and-neuropil-aggregates-in-huntington-s-disease-relationship-to/)
- [Gait variability and basal ganglia disorders: Stride‐to‐stride variations of gait cycle timing in parkinson's disease and Huntington's disease](https://scholariq.org/papers/gait-variability-and-basal-ganglia-disorders-stride-to-stride-variations-of-gait/)
- [Detection of Huntington's disease decades before diagnosis: the Predict-HD study](https://scholariq.org/papers/detection-of-huntington-s-disease-decades-before-diagnosis-the-predict-hd-study/)
- [Consensus classification of posterior cortical atrophy](https://scholariq.org/papers/consensus-classification-of-posterior-cortical-atrophy/)
- [The natural history of multiple system atrophy: a prospective European cohort study](https://scholariq.org/papers/the-natural-history-of-multiple-system-atrophy-a-prospective-european-cohort/)
- [Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity](https://scholariq.org/papers/cerebral-cortex-and-the-clinical-expression-of-huntington-s-disease-complexity/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.