# Genetics, Aging, and Longevity in Model Organisms

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/genetics-aging-and-longevity-in-model-organisms-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 2,107,096 |
| Description | This cluster of papers explores the molecular mechanisms underlying aging, longevity, and age-related diseases. It covers topics such as oxidative stress, genetic regulation of lifespan, the impact of caloric restriction, mitochondrial function, RNA interference, inflammaging, insulin signaling, and proteostasis. The research spans model organisms like C. elegans and Drosophila to mammalian studies, providing insights into the fundamental processes of aging. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T10676 |
| Works | 102,439 |

## Topic institutions

- [Harvard University](https://scholariq.org/institutions/harvard-university/)
- [Howard Hughes Medical Institute](https://scholariq.org/institutions/howard-hughes-medical-institute/)
- [Massachusetts General Hospital](https://scholariq.org/institutions/massachusetts-general-hospital/)
- [Yale University](https://scholariq.org/institutions/yale-university/)
- [Columbia University](https://scholariq.org/institutions/columbia-university/)
- [Massachusetts Institute of Technology](https://scholariq.org/institutions/massachusetts-institute-of-technology/)
- [University of California, San Francisco](https://scholariq.org/institutions/university-of-california-san-francisco/)
- [Harvard University Press](https://scholariq.org/institutions/harvard-university-press/)

## Topic researchers

Showing 12 of 20.

- [George Davey Smith](https://scholariq.org/researchers/george-davey-smith/)
- [Richard Durbin](https://scholariq.org/researchers/richard-durbin/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Stacey Gabriel](https://scholariq.org/researchers/stacey-gabriel/)
- [Robert Tibshirani](https://scholariq.org/researchers/robert-tibshirani/)
- [Peer Bork](https://scholariq.org/researchers/peer-bork/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Gad Getz](https://scholariq.org/researchers/gad-getz/)
- [Elaine R. Mardis](https://scholariq.org/researchers/elaine-r-mardis/)
- [Cyrus Cooper](https://scholariq.org/researchers/cyrus-cooper/)
- [Emelia J. Benjamin](https://scholariq.org/researchers/emelia-j-benjamin/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.