# Genomics, phytochemicals, and oxidative stress

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/genomics-phytochemicals-and-oxidative-stress/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the role of Nrf2 signaling in oxidative stress response, including its activation by oxidative stress, regulation of antioxidant gene expression, and its impact on cancer, inflammation, and chemoprevention. The Keap1-Nrf2-ARE pathway and the chemical diversity of glucosinolates are also central to this topic. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11332 |
| Works | 254 |

## Topic papers all

Showing 15 of 254.

- [Reactive oxygen species (ROS) as pleiotropic physiological signalling agents](https://scholariq.org/papers/reactive-oxygen-species-ros-as-pleiotropic-physiological-signalling-agents/)
- [Oxidative Stress and Antioxidant Defense](https://scholariq.org/papers/oxidative-stress-and-antioxidant-defense/)
- [Oxidative Stress](https://scholariq.org/papers/oxidative-stress/)
- [Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging](https://scholariq.org/papers/reactive-oxygen-species-toxicity-oxidative-stress-and-antioxidants-chronic/)
- [Flavonoids: antioxidants or signalling molecules?](https://scholariq.org/papers/flavonoids-antioxidants-or-signalling-molecules/)
- [Tobacco Smoke Carcinogens and Lung Cancer](https://scholariq.org/papers/tobacco-smoke-carcinogens-and-lung-cancer/)
- [Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases](https://scholariq.org/papers/lifestyle-oxidative-stress-and-antioxidants-back-and-forth-in-the/)
- [Tobacco carcinogens, their biomarkers and tobacco-induced cancer](https://scholariq.org/papers/tobacco-carcinogens-their-biomarkers-and-tobacco-induced-cancer/)
- [Radical-free biology of oxidative stress](https://scholariq.org/papers/radical-free-biology-of-oxidative-stress/)
- [Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer](https://scholariq.org/papers/dysfunctional-keap1-nrf2-interaction-in-non-small-cell-lung-cancer/)
- [AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1](https://scholariq.org/papers/ap-1-transcriptional-activity-is-regulated-by-a-direct-association-between/)
- [Molecular mechanisms of Nrf2‐mediated antioxidant response](https://scholariq.org/papers/molecular-mechanisms-of-nrf2-mediated-antioxidant-response/)
- [Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis](https://scholariq.org/papers/activation-of-nrf2-antioxidant-signaling-attenuates-nf-b-inflammatory-response/)
- [Physiologically based pharmacokinetics and the risk assessment process for methylene chloride](https://scholariq.org/papers/physiologically-based-pharmacokinetics-and-the-risk-assessment-process-for/)
- [HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells](https://scholariq.org/papers/hspa5-regulates-ferroptotic-cell-death-in-cancer-cells/)

## Topic primary papers

Showing 15 of 83.

- [Tobacco Smoke Carcinogens and Lung Cancer](https://scholariq.org/papers/tobacco-smoke-carcinogens-and-lung-cancer/)
- [Tobacco carcinogens, their biomarkers and tobacco-induced cancer](https://scholariq.org/papers/tobacco-carcinogens-their-biomarkers-and-tobacco-induced-cancer/)
- [Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer](https://scholariq.org/papers/dysfunctional-keap1-nrf2-interaction-in-non-small-cell-lung-cancer/)
- [Molecular mechanisms of Nrf2‐mediated antioxidant response](https://scholariq.org/papers/molecular-mechanisms-of-nrf2-mediated-antioxidant-response/)
- [Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis](https://scholariq.org/papers/activation-of-nrf2-antioxidant-signaling-attenuates-nf-b-inflammatory-response/)
- [Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells](https://scholariq.org/papers/sulforaphane-a-dietary-component-of-broccoli-broccoli-sprouts-inhibits-breast/)
- [Multi-targeted prevention of cancer by sulforaphane](https://scholariq.org/papers/multi-targeted-prevention-of-cancer-by-sulforaphane/)
- [Nrf2, a multi‐organ protector?](https://scholariq.org/papers/nrf2-a-multi-organ-protector/)
- [Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics](https://scholariq.org/papers/cancer-chemoprevention-by-dietary-polyphenols-promising-role-for-epigenetics/)
- [Inhibition of Activator Protein-1, NF-κB, and MAPKs and Induction of Phase 2 Detoxifying Enzyme Activity by Chlorogenic Acid](https://scholariq.org/papers/inhibition-of-activator-protein-1-nf-b-and-mapks-and-induction-of-phase-2/)
- [Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species](https://scholariq.org/papers/sulforaphane-induced-cell-death-in-human-prostate-cancer-cells-is-initiated-by/)
- [Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1](https://scholariq.org/papers/decline-in-nrf2-regulated-antioxidants-in-chronic-obstructive-pulmonary-disease/)
- [Sulforaphane-induced G2/M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2-mediated Phosphorylation of Cell Division Cycle 25C](https://scholariq.org/papers/sulforaphane-induced-g2-m-phase-cell-cycle-arrest-involves-checkpoint-kinase-2/)
- [Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in <i>Apc</i> <sup>min</sup> mice](https://scholariq.org/papers/sulforaphane-inhibits-histone-deacetylase-in-vivo-and-suppresses-tumorigenesis/)
- [Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells](https://scholariq.org/papers/sulforaphane-inhibits-histone-deacetylase-activity-in-bph-1-lncap-and-pc-3/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.