# Glutathione Transferases and Polymorphisms

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/glutathione-transferases-and-polymorphisms/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of glutathione transferases, superoxide dismutase, and genetic polymorphisms in oxidative stress response, cancer resistance, drug metabolism, and cell signaling. It investigates the impact of antioxidant enzymes on disease susceptibility and drug resistance, as well as their structural and functional characteristics. The research also delves into the implications of oxidative stress in various diseases and the potential for targeting glutathione-related pathways in therapeutic interventions. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12187 |
| Works | 145 |

## Topic papers all

Showing 15 of 145.

- [Reactive oxygen species (ROS) as pleiotropic physiological signalling agents](https://scholariq.org/papers/reactive-oxygen-species-ros-as-pleiotropic-physiological-signalling-agents/)
- [Oxidative Stress and Antioxidant Defense](https://scholariq.org/papers/oxidative-stress-and-antioxidant-defense/)
- [A simple method for clinical assay of superoxide dismutase.](https://scholariq.org/papers/a-simple-method-for-clinical-assay-of-superoxide-dismutase/)
- [Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland](https://scholariq.org/papers/environmental-and-heritable-factors-in-the-causation-of-cancer-analyses-of/)
- [Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging](https://scholariq.org/papers/reactive-oxygen-species-toxicity-oxidative-stress-and-antioxidants-chronic/)
- [Tobacco carcinogens, their biomarkers and tobacco-induced cancer](https://scholariq.org/papers/tobacco-carcinogens-their-biomarkers-and-tobacco-induced-cancer/)
- [Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer](https://scholariq.org/papers/dysfunctional-keap1-nrf2-interaction-in-non-small-cell-lung-cancer/)
- [Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk](https://scholariq.org/papers/common-genetic-variation-in-cellular-transport-genes-and-epithelial-ovarian/)
- [Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis.](https://scholariq.org/papers/cytidine-methylation-of-regulatory-sequences-near-the-pi-class-glutathione-s/)
- [\[11\] Redox potential of GSH/GSSG couple: Assay and biological significance](https://scholariq.org/papers/11-redox-potential-of-gsh-gssg-couple-assay-and-biological-significance/)
- [Molecular mechanisms of Nrf2‐mediated antioxidant response](https://scholariq.org/papers/molecular-mechanisms-of-nrf2-mediated-antioxidant-response/)
- [Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis](https://scholariq.org/papers/activation-of-nrf2-antioxidant-signaling-attenuates-nf-b-inflammatory-response/)
- [Human prostate cancer risk factors](https://scholariq.org/papers/human-prostate-cancer-risk-factors/)
- [Physiologically based pharmacokinetics and the risk assessment process for methylene chloride](https://scholariq.org/papers/physiologically-based-pharmacokinetics-and-the-risk-assessment-process-for/)
- [Thioredoxin reductase](https://scholariq.org/papers/thioredoxin-reductase/)

## Topic primary papers

Showing 15 of 47.

- [Oxidative Stress and Antioxidant Defense](https://scholariq.org/papers/oxidative-stress-and-antioxidant-defense/)
- [Naturally Occurring Human Glutathione <i>S</i>‐transferase GSTP1‐1 Isoforms with Isoleucine and Valine in Position 104 Differ in Enzymic Properties](https://scholariq.org/papers/naturally-occurring-human-glutathione-i-s-i-transferase-gstp1-1-isoforms-with/)
- [Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.](https://scholariq.org/papers/superoxide-dismutase-and-catalase-conjugated-to-polyethylene-glycol-increases/)
- [The interplay of glutathione-related processes in antioxidant defense](https://scholariq.org/papers/the-interplay-of-glutathione-related-processes-in-antioxidant-defense/)
- [Antioxidative enzyme activities in human erythrocytes](https://scholariq.org/papers/antioxidative-enzyme-activities-in-human-erythrocytes/)
- [Differential expression of manganese superoxide dismutase and catalase in lung cancer.](https://scholariq.org/papers/differential-expression-of-manganese-superoxide-dismutase-and-catalase-in-lung/)
- [Mitochondrial Manganese-Superoxide Dismutase Expression in Ovarian Cancer](https://scholariq.org/papers/mitochondrial-manganese-superoxide-dismutase-expression-in-ovarian-cancer/)
- [Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.](https://scholariq.org/papers/susceptibility-to-hepatocellular-carcinoma-is-associated-with-genetic-variation/)
- [Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer](https://scholariq.org/papers/antioxidant-enzyme-expression-and-reactive-oxygen-species-damage-in-prostatic/)
- [Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase](https://scholariq.org/papers/suppression-of-the-malignant-phenotype-of-human-glioma-cells-by-overexpression/)
- [Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice](https://scholariq.org/papers/nrf2-expression-is-regulated-by-epigenetic-mechanisms-in-prostate-cancer-of/)
- [Glutathione conjugation as a bioactivation reaction](https://scholariq.org/papers/glutathione-conjugation-as-a-bioactivation-reaction/)
- [Cisplatin-Induced Long-Term Hearing Impairment Is Associated With Specific Glutathione <i>S</i>-Transferase Genotypes in Testicular Cancer Survivors](https://scholariq.org/papers/cisplatin-induced-long-term-hearing-impairment-is-associated-with-specific/)
- [Formation of 8‐hydroxy‐2′‐deoxyguanosine and 4‐hydroxy‐2‐nonenal‐modified proteins in human renal‐cell carcinoma](https://scholariq.org/papers/formation-of-8-hydroxy-2-deoxyguanosine-and-4-hydroxy-2-nonenal-modified/)
- [Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate](https://scholariq.org/papers/inhibition-of-rat-and-human-glutathione-s-transferase-isoenzymes-by-ethacrynic/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.