# Hemoglobin structure and function

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/hemoglobin-structure-and-function/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the function, regulation, and physiological impact of hemoglobin and related proteins in vertebrates. It covers topics such as scavenger receptor CD163 expression, neuroglobin and myoglobin function, haptoglobin phenotype, nitric oxide dioxygenase activity, and the role of flavohemoglobins in detoxifying nitric oxide. The papers also discuss the use of hemoglobin-based oxygen carriers and their potential impact on cardiovascular disease. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12094 |
| Works | 82 |

## Topic papers all

Showing 15 of 82.

- [Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.](https://scholariq.org/papers/nitric-oxide-circulates-in-mammalian-plasma-primarily-as-an-s-nitroso-adduct-of/)
- [Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury](https://scholariq.org/papers/endocytic-delivery-of-lipocalin-siderophore-iron-complex-rescues-the-kidney-from/)
- [Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat.](https://scholariq.org/papers/induction-of-heme-oxygenase-is-a-rapid-protective-response-in-rhabdomyolysis-in/)
- [Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease](https://scholariq.org/papers/heme-triggers-tlr4-signaling-leading-to-endothelial-cell-activation-and-vaso/)
- [Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death](https://scholariq.org/papers/cell-free-hemoglobin-based-blood-substitutes-and-risk-of-myocardial-infarction/)
- [Nitrate and nitrite in biology, nutrition and therapeutics](https://scholariq.org/papers/nitrate-and-nitrite-in-biology-nutrition-and-therapeutics/)
- [Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage.](https://scholariq.org/papers/endothelial-cell-heme-uptake-from-heme-proteins-induction-of-sensitization-and/)
- [A Modification of the Benzidine Method for Measurement of Hemoglobin in Plasma and Urine](https://scholariq.org/papers/a-modification-of-the-benzidine-method-for-measurement-of-hemoglobin-in-plasma/)
- [Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX](https://scholariq.org/papers/crystal-structure-of-the-catalytic-domain-of-the-tumor-associated-human-carbonic/)
- [Left Ventricular Unloading Is Associated With Lower Mortality in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation](https://scholariq.org/papers/left-ventricular-unloading-is-associated-with-lower-mortality-in-patients-with/)
- [A Central Role for Free Heme in the Pathogenesis of Severe Sepsis](https://scholariq.org/papers/a-central-role-for-free-heme-in-the-pathogenesis-of-severe-sepsis/)
- [Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.](https://scholariq.org/papers/superoxide-dismutase-and-catalase-conjugated-to-polyethylene-glycol-increases/)
- [Do Perfluoroalkyl Compounds Impair Human Semen Quality?](https://scholariq.org/papers/do-perfluoroalkyl-compounds-impair-human-semen-quality/)
- [Oxygen Reduction by Nitric-oxide Synthases](https://scholariq.org/papers/oxygen-reduction-by-nitric-oxide-synthases/)
- [Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin](https://scholariq.org/papers/hemolysis-associated-endothelial-dysfunction-mediated-by-accelerated-no/)

## Topic primary papers

- [Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death](https://scholariq.org/papers/cell-free-hemoglobin-based-blood-substitutes-and-risk-of-myocardial-infarction/)
- [Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin](https://scholariq.org/papers/hemolysis-associated-endothelial-dysfunction-mediated-by-accelerated-no/)
- [Bench-to-bedside review: microvascular dysfunction in sepsis--hemodynamics, oxygen transport, and nitric oxide.](https://scholariq.org/papers/bench-to-bedside-review-microvascular-dysfunction-in-sepsis-hemodynamics-oxygen/)
- [Role of erythrocyte in regulating local O <sub>2</sub> delivery mediated by hemoglobin oxygenation](https://scholariq.org/papers/role-of-erythrocyte-in-regulating-local-o-sub-2-sub-delivery-mediated-by/)
- [Measurement of Hemoperfusion and Oxygen Sufficiency in Gastric Mucosa In Vivo](https://scholariq.org/papers/measurement-of-hemoperfusion-and-oxygen-sufficiency-in-gastric-mucosa-in-vivo/)
- [Theoretical Models of Microvascular Oxygen Transport to Tissue](https://scholariq.org/papers/theoretical-models-of-microvascular-oxygen-transport-to-tissue/)
- [Molecular Mechanism of AHSP-Mediated Stabilization of α-Hemoglobin](https://scholariq.org/papers/molecular-mechanism-of-ahsp-mediated-stabilization-of-hemoglobin/)
- [Randomized Trial of Diaspirin Cross-linked Hemoglobin Solution as an Alternative to Blood Transfusion after Cardiac Surgery](https://scholariq.org/papers/randomized-trial-of-diaspirin-cross-linked-hemoglobin-solution-as-an-alternative/)
- [When Blood Is Not an Option: Factors Affecting Survival After the Use of a Hemoglobin-Based Oxygen Carrier in 54 Patients with Life-Threatening Anemia](https://scholariq.org/papers/when-blood-is-not-an-option-factors-affecting-survival-after-the-use-of-a/)
- [The anatomy of microbial cell state transitions in response to oxygen](https://scholariq.org/papers/the-anatomy-of-microbial-cell-state-transitions-in-response-to-oxygen/)
- [Evidence for proximal control of ligand specificity in hemeproteins: Absorption and Raman studies of cryogenically trapped photoproducts of ligand bound myoglobins](https://scholariq.org/papers/evidence-for-proximal-control-of-ligand-specificity-in-hemeproteins-absorption/)
- [Oxygen free radical regulation of rat splanchnic blood flow.](https://scholariq.org/papers/oxygen-free-radical-regulation-of-rat-splanchnic-blood-flow/)
- [Solution structure of a mammalian PCB-binding protein in complex with a PCB](https://scholariq.org/papers/solution-structure-of-a-mammalian-pcb-binding-protein-in-complex-with-a-pcb/)
- [Microvascular Flow Modeling using <i>In Vivo</i> Hemodynamic Measurements in Reconstructed 3D Capillary Networks](https://scholariq.org/papers/microvascular-flow-modeling-using-i-in-vivo-i-hemodynamic-measurements-in/)
- [The oxygen-release capacity of red blood cells in insulin-dependent diabetics after artificial pancreas](https://scholariq.org/papers/the-oxygen-release-capacity-of-red-blood-cells-in-insulin-dependent-diabetics/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
