# Hippo pathway signaling and YAP/TAZ

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/hippo-pathway-signaling-and-yap-taz/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of the Hippo signaling pathway, particularly the involvement of YAP/TAZ, in mechanotransduction, cell proliferation, tissue growth control, organ size control, and its implications in cancer and stem cell regulation. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12065 |
| Works | 89 |

## Topic papers all

Showing 15 of 89.

- [Cooperation between mDia1 and ROCK in Rho-induced actin reorganization](https://scholariq.org/papers/cooperation-between-mdia1-and-rock-in-rho-induced-actin-reorganization/)
- [Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer](https://scholariq.org/papers/yap1-activation-enables-bypass-of-oncogenic-kras-addiction-in-pancreatic-cancer/)
- [Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver](https://scholariq.org/papers/hippo-signaling-is-a-potent-in-vivo-growth-and-tumor-suppressor-pathway-in-the/)
- [Genetic landscape of esophageal squamous cell carcinoma](https://scholariq.org/papers/genetic-landscape-of-esophageal-squamous-cell-carcinoma/)
- [STRUCTURE AND FUNCTION OF SIGNAL-TRANSDUCING GTP-BINDING PROTEINS](https://scholariq.org/papers/structure-and-function-of-signal-transducing-gtp-binding-proteins/)
- [Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression](https://scholariq.org/papers/circular-rna-larp4-inhibits-cell-proliferation-and-invasion-of-gastric-cancer-by/)
- [Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer](https://scholariq.org/papers/comprehensive-molecular-characterization-of-the-hippo-signaling-pathway-in/)
- [Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway](https://scholariq.org/papers/treatment-induced-tumor-dormancy-through-yap-mediated-transcriptional/)
- [Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis](https://scholariq.org/papers/fat1-deletion-promotes-hybrid-emt-state-tumour-stemness-and-metastasis/)
- [Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos](https://scholariq.org/papers/polarity-dependent-distribution-of-angiomotin-localizes-hippo-signaling-in/)
- [Structural insights into the YAP and TEAD complex](https://scholariq.org/papers/structural-insights-into-the-yap-and-tead-complex/)
- [Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion](https://scholariq.org/papers/dynamic-and-static-interactions-between-p120-catenin-and-e-cadherin-regulate-the/)
- [FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor](https://scholariq.org/papers/fgfr-genetic-alterations-predict-for-sensitivity-to-nvp-bgj398-a-selective-pan/)
- [LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells](https://scholariq.org/papers/lncbrm-initiates-yap1-signalling-activation-to-drive-self-renewal-of-liver/)
- [The phenotype of human STK4 deficiency](https://scholariq.org/papers/the-phenotype-of-human-stk4-deficiency/)

## Topic primary papers

Showing 15 of 47.

- [Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer](https://scholariq.org/papers/yap1-activation-enables-bypass-of-oncogenic-kras-addiction-in-pancreatic-cancer/)
- [Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver](https://scholariq.org/papers/hippo-signaling-is-a-potent-in-vivo-growth-and-tumor-suppressor-pathway-in-the/)
- [STRUCTURE AND FUNCTION OF SIGNAL-TRANSDUCING GTP-BINDING PROTEINS](https://scholariq.org/papers/structure-and-function-of-signal-transducing-gtp-binding-proteins/)
- [Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer](https://scholariq.org/papers/comprehensive-molecular-characterization-of-the-hippo-signaling-pathway-in/)
- [Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway](https://scholariq.org/papers/treatment-induced-tumor-dormancy-through-yap-mediated-transcriptional/)
- [Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis](https://scholariq.org/papers/fat1-deletion-promotes-hybrid-emt-state-tumour-stemness-and-metastasis/)
- [Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos](https://scholariq.org/papers/polarity-dependent-distribution-of-angiomotin-localizes-hippo-signaling-in/)
- [Structural insights into the YAP and TEAD complex](https://scholariq.org/papers/structural-insights-into-the-yap-and-tead-complex/)
- [The phenotype of human STK4 deficiency](https://scholariq.org/papers/the-phenotype-of-human-stk4-deficiency/)
- [A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway](https://scholariq.org/papers/a-genetic-screen-identifies-an-lkb1-mark-signalling-axis-controlling-the-hippo/)
- [MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1](https://scholariq.org/papers/microrna-135b-promotes-lung-cancer-metastasis-by-regulating-multiple-targets-in/)
- [YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis](https://scholariq.org/papers/yap-regulates-actin-dynamics-through-arhgap29-and-promotes-metastasis/)
- [A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions](https://scholariq.org/papers/a-tight-junction-associated-merlin-angiomotin-complex-mediates-merlin-s/)
- [Targeting Cancer Stem Cells: A Strategy for Effective Eradication of Cancer](https://scholariq.org/papers/targeting-cancer-stem-cells-a-strategy-for-effective-eradication-of-cancer/)
- [SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis](https://scholariq.org/papers/set1a-mediated-mono-methylation-at-k342-regulates-yap-activation-by-blocking-its/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.