# Hydrogen's biological and therapeutic effects

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/hydrogen-s-biological-and-therapeutic-effects/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the therapeutic applications of molecular hydrogen therapy, focusing on its potential as an antioxidant and anti-inflammatory agent. The research covers a wide range of medical conditions, including neurodegenerative diseases, diabetes, cardiovascular disorders, and ischemia-reperfusion injuries. Molecular hydrogen is investigated for its ability to reduce oxidative stress, alleviate inflammation, and provide neuroprotection in various disease models. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t13775 |
| Works | 46 |

## Topic papers all

Showing 15 of 46.

- [Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology](https://scholariq.org/papers/defining-roles-of-specific-reactive-oxygen-species-ros-in-cell-biology-and/)
- [The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview](https://scholariq.org/papers/the-antioxidant-immunomodulatory-and-anti-inflammatory-activities-of-spirulina/)
- [Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome](https://scholariq.org/papers/manipulation-of-dietary-short-chain-carbohydrates-alters-the-pattern-of-gas/)
- [Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury](https://scholariq.org/papers/inhalation-of-hydrogen-gas-reduces-infarct-size-in-the-rat-model-of-myocardial/)
- [<i>Portulaca oleracea</i>L.: A Review of Phytochemistry and Pharmacological Effects](https://scholariq.org/papers/i-portulaca-oleracea-i-l-a-review-of-phytochemistry-and-pharmacological-effects/)
- [Nitrate, nitrite and N-nitroso compounds](https://scholariq.org/papers/nitrate-nitrite-and-n-nitroso-compounds/)
- [Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4](https://scholariq.org/papers/ischaemic-preconditioning-regulated-mir-21-protects-heart-against-ischaemia/)
- [Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries](https://scholariq.org/papers/oxidative-stress-and-inflammation-in-acute-and-chronic-lung-injuries/)
- [Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study](https://scholariq.org/papers/effectiveness-of-hydrogen-rich-water-on-antioxidant-status-of-subjects-with/)
- [Sodium-Hydrogen Exchange Inhibition by Cariporide to Reduce the Risk of Ischemic Cardiac Events in Patients Undergoing Coronary Artery Bypass Grafting: Results of the EXPEDITION Study](https://scholariq.org/papers/sodium-hydrogen-exchange-inhibition-by-cariporide-to-reduce-the-risk-of-ischemic/)
- [MicroRNA 23b Regulates Autophagy Associated With Radioresistance of Pancreatic Cancer Cells](https://scholariq.org/papers/microrna-23b-regulates-autophagy-associated-with-radioresistance-of-pancreatic/)
- [Water Intoxication: A Possible Complication During Endurance Exercise☆](https://scholariq.org/papers/water-intoxication-a-possible-complication-during-endurance-exercise/)
- [Neuroprotective effects of hydrogen saline in neonatal hypoxia–ischemia rat model](https://scholariq.org/papers/neuroprotective-effects-of-hydrogen-saline-in-neonatal-hypoxia-ischemia-rat/)
- [Ringer’s ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats](https://scholariq.org/papers/ringer-s-ethyl-pyruvate-solution-ameliorates-ischemia-reperfusion-induced/)
- [Cadmium Increases HIF-1 and VEGF Expression through ROS, ERK, and AKT Signaling Pathways and Induces Malignant Transformation of Human Bronchial Epithelial Cells](https://scholariq.org/papers/cadmium-increases-hif-1-and-vegf-expression-through-ros-erk-and-akt-signaling/)

## Topic primary papers

- [Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome](https://scholariq.org/papers/manipulation-of-dietary-short-chain-carbohydrates-alters-the-pattern-of-gas/)
- [Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury](https://scholariq.org/papers/inhalation-of-hydrogen-gas-reduces-infarct-size-in-the-rat-model-of-myocardial/)
- [Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries](https://scholariq.org/papers/oxidative-stress-and-inflammation-in-acute-and-chronic-lung-injuries/)
- [Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study](https://scholariq.org/papers/effectiveness-of-hydrogen-rich-water-on-antioxidant-status-of-subjects-with/)
- [Neuroprotective effects of hydrogen saline in neonatal hypoxia–ischemia rat model](https://scholariq.org/papers/neuroprotective-effects-of-hydrogen-saline-in-neonatal-hypoxia-ischemia-rat/)
- [Microbiota-Derived Hydrogen Fuels Salmonella Typhimurium Invasion of the Gut Ecosystem](https://scholariq.org/papers/microbiota-derived-hydrogen-fuels-salmonella-typhimurium-invasion-of-the-gut/)
- [Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats](https://scholariq.org/papers/hydrogen-rich-saline-protects-against-intestinal-ischemia-reperfusion-injury-in/)
- [Hydrogen-Rich Saline Protects Myocardium Against Ischemia/Reperfusion Injury in Rats](https://scholariq.org/papers/hydrogen-rich-saline-protects-myocardium-against-ischemia-reperfusion-injury-in/)
- [Metal–Organic‐Framework‐Based Hydrogen‐Release Platform for Multieffective <i>Helicobacter Pylori</i> Targeting Therapy and Intestinal Flora Protective Capabilities](https://scholariq.org/papers/metal-organic-framework-based-hydrogen-release-platform-for-multieffective-i/)
- [Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice](https://scholariq.org/papers/hydrogen-rich-water-prevents-progression-of-nonalcoholic-steatohepatitis-and/)
- [Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome](https://scholariq.org/papers/hydrogen-rich-water-decreases-serum-ldl-cholesterol-levels-and-improves-hdl/)
- [Hydrogen-rich water regulates cucumber adventitious root development in a heme oxygenase-1/carbon monoxide-dependent manner](https://scholariq.org/papers/hydrogen-rich-water-regulates-cucumber-adventitious-root-development-in-a-heme/)
- [Lactulose ameliorates cerebral ischemia–reperfusion injury in ratsby inducing hydrogen by activating Nrf2 expression](https://scholariq.org/papers/lactulose-ameliorates-cerebral-ischemia-reperfusion-injury-in-ratsby-inducing/)
- [Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation](https://scholariq.org/papers/hydrogen-rich-saline-promotes-microglia-m2-polarization-and-complement-mediated/)
- [Adverse Effects of Long-Term Ice-Cold Water Drink on Rat Liver Function and Histology](https://scholariq.org/papers/adverse-effects-of-long-term-ice-cold-water-drink-on-rat-liver-function-and/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.