# IL-33, ST2, and ILC Pathways

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/il-33-st2-and-ilc-pathways/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of innate lymphoid cells, particularly their interaction with IL-33, in regulating type 2 immunity, tissue homeostasis, mucosal immunity, allergic inflammation, and the interplay with the adaptive immune system. It also delves into their involvement in various inflammatory diseases and their influence on regulatory T cells. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t12528 |
| Works | 181 |

## Topic papers all

Showing 15 of 181.

- [A Genome-Wide Association Study Identifies <i>IL23R</i> as an Inflammatory Bowel Disease Gene](https://scholariq.org/papers/a-genome-wide-association-study-identifies-i-il23r-i-as-an-inflammatory-bowel/)
- [Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease](https://scholariq.org/papers/genome-wide-association-defines-more-than-30-distinct-susceptibility-loci-for/)
- [Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci](https://scholariq.org/papers/genome-wide-meta-analysis-increases-to-71-the-number-of-confirmed-crohn-s/)
- [Eosinophilic esophagitis: Updated consensus recommendations for children and adults](https://scholariq.org/papers/eosinophilic-esophagitis-updated-consensus-recommendations-for-children-and/)
- [Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma](https://scholariq.org/papers/dupilumab-efficacy-and-safety-in-moderate-to-severe-uncontrolled-asthma/)
- [Allergy, Parasites, and the Hygiene Hypothesis](https://scholariq.org/papers/allergy-parasites-and-the-hygiene-hypothesis/)
- [A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells](https://scholariq.org/papers/a-key-role-for-autophagy-and-the-autophagy-gene-atg16l1-in-mouse-and-human/)
- [Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes](https://scholariq.org/papers/germline-mutations-in-the-extracellular-domains-of-the-55-kda-tnf-receptor-tnfr1/)
- [The maternal microbiota drives early postnatal innate immune development](https://scholariq.org/papers/the-maternal-microbiota-drives-early-postnatal-innate-immune-development/)
- [A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity](https://scholariq.org/papers/a-human-natural-killer-cell-subset-provides-an-innate-source-of-il-22-for/)
- [Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma](https://scholariq.org/papers/efficacy-and-safety-of-dupilumab-in-glucocorticoid-dependent-severe-asthma/)
- [A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1](https://scholariq.org/papers/a-genome-wide-association-study-identifies-new-psoriasis-susceptibility-loci-and/)
- [STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing](https://scholariq.org/papers/stat3-links-il-22-signaling-in-intestinal-epithelial-cells-to-mucosal-wound/)
- [Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity](https://scholariq.org/papers/intestinal-microbiota-derived-short-chain-fatty-acids-regulation-of-immune-cell/)
- [Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures](https://scholariq.org/papers/long-term-survival-for-patients-with-non-small-cell-lung-cancer-with/)

## Topic primary papers

Showing 15 of 31.

- [A Genome-Wide Association Study Identifies <i>IL23R</i> as an Inflammatory Bowel Disease Gene](https://scholariq.org/papers/a-genome-wide-association-study-identifies-i-il23r-i-as-an-inflammatory-bowel/)
- [STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing](https://scholariq.org/papers/stat3-links-il-22-signaling-in-intestinal-epithelial-cells-to-mucosal-wound/)
- [Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity](https://scholariq.org/papers/intestinal-microbiota-derived-short-chain-fatty-acids-regulation-of-immune-cell/)
- [A cellular census of human lungs identifies novel cell states in health and in asthma](https://scholariq.org/papers/a-cellular-census-of-human-lungs-identifies-novel-cell-states-in-health-and-in/)
- [Cells of the human intestinal tract mapped across space and time](https://scholariq.org/papers/cells-of-the-human-intestinal-tract-mapped-across-space-and-time/)
- [Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation](https://scholariq.org/papers/systemic-human-ilc-precursors-provide-a-substrate-for-tissue-ilc-differentiation/)
- [Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes](https://scholariq.org/papers/interleukin-22-alleviates-metabolic-disorders-and-restores-mucosal-immunity-in/)
- [The IL-20 subfamily of cytokines — from host defence to tissue homeostasis](https://scholariq.org/papers/the-il-20-subfamily-of-cytokines-from-host-defence-to-tissue-homeostasis/)
- [Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis](https://scholariq.org/papers/epithelial-derived-il-33-and-its-receptor-st2-are-dysregulated-in-ulcerative/)
- [High-Sensitivity ST2 for Prediction of Adverse Outcomes in Chronic Heart Failure](https://scholariq.org/papers/high-sensitivity-st2-for-prediction-of-adverse-outcomes-in-chronic-heart-failure/)
- [Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation](https://scholariq.org/papers/regulatory-innate-lymphoid-cells-control-innate-intestinal-inflammation/)
- [Single base polymorphism at −511 in the human interleukin-1β gene (IL1β)](https://scholariq.org/papers/single-base-polymorphism-at-511-in-the-human-interleukin-1-gene-il1/)
- [The roles of tertiary lymphoid structures in chronic diseases](https://scholariq.org/papers/the-roles-of-tertiary-lymphoid-structures-in-chronic-diseases/)
- [Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer](https://scholariq.org/papers/transdifferentiation-of-tumor-infiltrating-innate-lymphoid-cells-during/)
- [Meta-Analysis of Soluble Suppression of Tumorigenicity-2 and Prognosis in Acute Heart Failure](https://scholariq.org/papers/meta-analysis-of-soluble-suppression-of-tumorigenicity-2-and-prognosis-in-acute/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
