# Immune Response and Inflammation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/immune-response-and-inflammation/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the recognition and signaling pathways of innate immunity, particularly through Toll-like receptors and pattern recognition receptors. It explores the role of these receptors in pathogen recognition, inflammation, antiviral responses, and the regulation of adaptive immunity. The cluster also delves into the molecular mechanisms and mediators involved in innate immune responses. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t10371 |
| Works | 510 |

## Topic papers all

Showing 15 of 510.

- [Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study](https://scholariq.org/papers/global-regional-and-national-sepsis-incidence-and-mortality-1990-2017-analysis/)
- [Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016](https://scholariq.org/papers/surviving-sepsis-campaign-international-guidelines-for-management-of-sepsis-and/)
- [NF-κB: a key role in inflammatory diseases](https://scholariq.org/papers/nf-b-a-key-role-in-inflammatory-diseases/)
- [Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses](https://scholariq.org/papers/differential-roles-of-mda5-and-rig-i-helicases-in-the-recognition-of-rna-viruses/)
- [Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016](https://scholariq.org/papers/surviving-sepsis-campaign-international-guidelines-for-management-of-sepsis-and-2/)
- [The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5](https://scholariq.org/papers/the-innate-immune-response-to-bacterial-flagellin-is-mediated-by-toll-like/)
- [Genomic responses in mouse models poorly mimic human inflammatory diseases](https://scholariq.org/papers/genomic-responses-in-mouse-models-poorly-mimic-human-inflammatory-diseases/)
- [Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation](https://scholariq.org/papers/effects-of-a-polymorphism-in-the-human-tumor-necrosis-factor-promoter-on/)
- [Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens](https://scholariq.org/papers/interleukin-22-mediates-early-host-defense-against-attaching-and-effacing/)
- [Control of microglial neurotoxicity by the fractalkine receptor](https://scholariq.org/papers/control-of-microglial-neurotoxicity-by-the-fractalkine-receptor/)
- [Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility](https://scholariq.org/papers/multiple-sclerosis-genomic-map-implicates-peripheral-immune-cells-and-microglia/)
- [CD40-CD40 ligand](https://scholariq.org/papers/cd40-cd40-ligand/)
- [Regulation of lung injury and repair by Toll-like receptors and hyaluronan](https://scholariq.org/papers/regulation-of-lung-injury-and-repair-by-toll-like-receptors-and-hyaluronan/)
- [Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria](https://scholariq.org/papers/caspase-1-induced-pyroptosis-is-an-innate-immune-effector-mechanism-against/)
- [Contribution of Neutrophils to Acute Lung Injury](https://scholariq.org/papers/contribution-of-neutrophils-to-acute-lung-injury/)

## Topic primary papers

Showing 15 of 117.

- [The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5](https://scholariq.org/papers/the-innate-immune-response-to-bacterial-flagellin-is-mediated-by-toll-like/)
- [Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation](https://scholariq.org/papers/effects-of-a-polymorphism-in-the-human-tumor-necrosis-factor-promoter-on/)
- [Regulation of lung injury and repair by Toll-like receptors and hyaluronan](https://scholariq.org/papers/regulation-of-lung-injury-and-repair-by-toll-like-receptors-and-hyaluronan/)
- [Epithelial NEMO links innate immunity to chronic intestinal inflammation](https://scholariq.org/papers/epithelial-nemo-links-innate-immunity-to-chronic-intestinal-inflammation/)
- [LPS, TLR4 and infectious disease diversity](https://scholariq.org/papers/lps-tlr4-and-infectious-disease-diversity/)
- [An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles.](https://scholariq.org/papers/an-allelic-polymorphism-within-the-human-tumor-necrosis-factor-alpha-promoter/)
- [Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways](https://scholariq.org/papers/saturated-fatty-acids-activate-tlr-mediated-proinflammatory-signaling-pathways/)
- [Structural Basis of TLR5-Flagellin Recognition and Signaling](https://scholariq.org/papers/structural-basis-of-tlr5-flagellin-recognition-and-signaling/)
- [Human Toll-like receptor 4 recognizes host-specific LPS modifications](https://scholariq.org/papers/human-toll-like-receptor-4-recognizes-host-specific-lps-modifications/)
- [Inflammatory cytokines and cell response in surgery](https://scholariq.org/papers/inflammatory-cytokines-and-cell-response-in-surgery/)
- [Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis](https://scholariq.org/papers/fortifying-the-barrier-the-impact-of-lipid-a-remodelling-on-bacterial/)
- [Pushing the envelope: LPS modifications and their consequences](https://scholariq.org/papers/pushing-the-envelope-lps-modifications-and-their-consequences/)
- [Reciprocal Modulation of Toll-like Receptor-4 Signaling Pathways Involving MyD88 and Phosphatidylinositol 3-Kinase/AKT by Saturated and Polyunsaturated Fatty Acids](https://scholariq.org/papers/reciprocal-modulation-of-toll-like-receptor-4-signaling-pathways-involving-myd88/)
- [Saturated fatty acids trigger TLR4-mediated inflammatory response](https://scholariq.org/papers/saturated-fatty-acids-trigger-tlr4-mediated-inflammatory-response/)
- [Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections](https://scholariq.org/papers/host-innate-immune-receptors-and-beyond-making-sense-of-microbial-infections/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.