# Inflammasome and immune disorders

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/inflammasome-and-immune-disorders/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the molecular mechanisms of inflammasome activation, regulation, and its role in inflammatory responses, cell death (pyroptosis), and immune-related diseases. It covers topics such as NLRP3 inflammasome, interleukin-1, caspase-1, and the involvement of mitochondria in inflammasome activation. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11078 |
| Works | 398 |

## Topic papers all

Showing 15 of 398.

- [Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease](https://scholariq.org/papers/antiinflammatory-therapy-with-canakinumab-for-atherosclerotic-disease/)
- [Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction](https://scholariq.org/papers/efficacy-and-safety-of-low-dose-colchicine-after-myocardial-infarction/)
- [Colchicine in Patients with Chronic Coronary Disease](https://scholariq.org/papers/colchicine-in-patients-with-chronic-coronary-disease/)
- [Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)](https://scholariq.org/papers/efficacy-and-safety-of-ustekinumab-a-human-interleukin-12-23-monoclonal-antibody/)
- [STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors](https://scholariq.org/papers/sting-dependent-cytosolic-dna-sensing-mediates-innate-immune-recognition-of/)
- [Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome](https://scholariq.org/papers/neutrophil-extracellular-traps-contribute-to-immunothrombosis-in-covid-19-acute/)
- [Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes](https://scholariq.org/papers/germline-mutations-in-the-extracellular-domains-of-the-55-kda-tnf-receptor-tnfr1/)
- [Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria](https://scholariq.org/papers/caspase-1-induced-pyroptosis-is-an-innate-immune-effector-mechanism-against/)
- [Small-Vessel Vasculitis](https://scholariq.org/papers/small-vessel-vasculitis/)
- [Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial](https://scholariq.org/papers/effect-of-interleukin-1-inhibition-with-canakinumab-on-incident-lung-cancer-in/)
- [Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes](https://scholariq.org/papers/activation-of-the-nlrp3-inflammasome-by-islet-amyloid-polypeptide-provides-a/)
- [Low-Dose Methotrexate for the Prevention of Atherosclerotic Events](https://scholariq.org/papers/low-dose-methotrexate-for-the-prevention-of-atherosclerotic-events/)
- [Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors](https://scholariq.org/papers/recent-advances-in-the-mechanisms-of-nlrp3-inflammasome-activation-and-its/)
- [Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock](https://scholariq.org/papers/cytoplasmic-lps-activates-caspase-11-implications-in-tlr4-independent-endotoxic/)
- [Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure](https://scholariq.org/papers/mitochondrial-dna-that-escapes-from-autophagy-causes-inflammation-and-heart/)

## Topic primary papers

Showing 15 of 164.

- [Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease](https://scholariq.org/papers/antiinflammatory-therapy-with-canakinumab-for-atherosclerotic-disease/)
- [Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction](https://scholariq.org/papers/efficacy-and-safety-of-low-dose-colchicine-after-myocardial-infarction/)
- [Colchicine in Patients with Chronic Coronary Disease](https://scholariq.org/papers/colchicine-in-patients-with-chronic-coronary-disease/)
- [Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes](https://scholariq.org/papers/germline-mutations-in-the-extracellular-domains-of-the-55-kda-tnf-receptor-tnfr1/)
- [Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria](https://scholariq.org/papers/caspase-1-induced-pyroptosis-is-an-innate-immune-effector-mechanism-against/)
- [Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial](https://scholariq.org/papers/effect-of-interleukin-1-inhibition-with-canakinumab-on-incident-lung-cancer-in/)
- [Low-Dose Methotrexate for the Prevention of Atherosclerotic Events](https://scholariq.org/papers/low-dose-methotrexate-for-the-prevention-of-atherosclerotic-events/)
- [Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors](https://scholariq.org/papers/recent-advances-in-the-mechanisms-of-nlrp3-inflammasome-activation-and-its/)
- [Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock](https://scholariq.org/papers/cytoplasmic-lps-activates-caspase-11-implications-in-tlr4-independent-endotoxic/)
- [The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation](https://scholariq.org/papers/the-adaptor-mavs-promotes-nlrp3-mitochondrial-localization-and-inflammasome/)
- [Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu](https://scholariq.org/papers/interleukin-18-is-a-unique-cytokine-that-stimulates-both-th1-and-th2-responses/)
- [STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3](https://scholariq.org/papers/sting-irf3-contributes-to-lipopolysaccharide-induced-cardiac-dysfunction/)
- [Colchicine poisoning: the dark side of an ancient drug](https://scholariq.org/papers/colchicine-poisoning-the-dark-side-of-an-ancient-drug/)
- [Mutations in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome](https://scholariq.org/papers/mutations-in-the-gene-encoding-mevalonate-kinase-cause-hyper-igd-and-periodic/)
- [Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens](https://scholariq.org/papers/noncanonical-inflammasome-activation-of-caspase-4-caspase-11-mediates-epithelial/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.