# Inflammation biomarkers and pathways

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/inflammation-biomarkers-and-pathways/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of triggering receptor expressed on myeloid cells-1 (TREM-1) and endocan in inflammatory responses, sepsis, and various inflammatory diseases. It investigates their impact on immune cells such as macrophages and neutrophils, as well as their potential as diagnostic markers for conditions like pneumonia and septic shock. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t14165 |
| Works | 73 |

## Topic papers all

Showing 15 of 73.

- [Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease](https://scholariq.org/papers/variant-of-i-trem2-i-associated-with-the-risk-of-alzheimer-s-disease/)
- [Human Endothelial Progenitor Cells From Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation Into Vascular Structures](https://scholariq.org/papers/human-endothelial-progenitor-cells-from-type-ii-diabetics-exhibit-impaired/)
- [Mobilization of Endothelial Progenitor Cells in Patients With Acute Myocardial Infarction](https://scholariq.org/papers/mobilization-of-endothelial-progenitor-cells-in-patients-with-acute-myocardial/)
- [Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease](https://scholariq.org/papers/rare-coding-variants-in-plcg2-abi3-and-trem2-implicate-microglial-mediated/)
- [SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology](https://scholariq.org/papers/sars-cov-2-triggered-neutrophil-extracellular-traps-mediate-covid-19-pathology/)
- [TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis](https://scholariq.org/papers/trem2-mutations-implicated-in-neurodegeneration-impair-cell-surface-transport/)
- [Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis](https://scholariq.org/papers/cytokine-profiles-as-markers-of-disease-severity-in-sepsis-a-multiplex-analysis/)
- [Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model](https://scholariq.org/papers/anti-human-trem2-induces-microglia-proliferation-and-reduces-pathology-in-an/)
- [TNF signaling drives myeloid-derived suppressor cell accumulation](https://scholariq.org/papers/tnf-signaling-drives-myeloid-derived-suppressor-cell-accumulation/)
- [Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease](https://scholariq.org/papers/increased-cerebrospinal-fluid-soluble-trem2-concentration-in-alzheimer-s-disease/)
- [The <i>MS4A</i> gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk](https://scholariq.org/papers/the-i-ms4a-i-gene-cluster-is-a-key-modulator-of-soluble-trem2-and-alzheimer-s/)
- [Plasma Angiopoietin-2 Predicts the Onset of Acute Lung Injury in Critically Ill Patients](https://scholariq.org/papers/plasma-angiopoietin-2-predicts-the-onset-of-acute-lung-injury-in-critically-ill/)
- [Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)](https://scholariq.org/papers/endothelial-dysfunction-and-altered-endothelial-biomarkers-in-patients-with-post/)
- [Resistin is secreted from macrophages in atheromas and promotes atherosclerosis](https://scholariq.org/papers/resistin-is-secreted-from-macrophages-in-atheromas-and-promotes-atherosclerosis/)
- [TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage](https://scholariq.org/papers/trem-1-exacerbates-neuroinflammatory-injury-via-nlrp3-inflammasome-mediated/)

## Topic primary papers

- [TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis](https://scholariq.org/papers/trem2-mutations-implicated-in-neurodegeneration-impair-cell-surface-transport/)
- [The <i>MS4A</i> gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk](https://scholariq.org/papers/the-i-ms4a-i-gene-cluster-is-a-key-modulator-of-soluble-trem2-and-alzheimer-s/)
- [TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage](https://scholariq.org/papers/trem-1-exacerbates-neuroinflammatory-injury-via-nlrp3-inflammasome-mediated/)
- [TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer](https://scholariq.org/papers/trem-1-expression-in-tumor-associated-macrophages-and-clinical-outcome-in-lung/)
- [Endocan Expression Correlated with Poor Survival in Human Hepatocellular Carcinoma](https://scholariq.org/papers/endocan-expression-correlated-with-poor-survival-in-human-hepatocellular/)
- [Endocan, a new invasion and angiogenesis marker of pituitary adenomas](https://scholariq.org/papers/endocan-a-new-invasion-and-angiogenesis-marker-of-pituitary-adenomas/)
- [Serum Endocan Correlated With Stage of Chronic Kidney Disease and Deterioration in Renal Transplant Recipients](https://scholariq.org/papers/serum-endocan-correlated-with-stage-of-chronic-kidney-disease-and-deterioration/)
- [Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE2 pathway](https://scholariq.org/papers/rheumatoid-arthritis-synovial-fibroblasts-promote-trem-1-expression-in-monocytes/)
- [Concentration and value of endocan on outcome in adult patients after severe sepsis](https://scholariq.org/papers/concentration-and-value-of-endocan-on-outcome-in-adult-patients-after-severe/)
- [Serum soluble TREM2 is an independent biomarker associated with coronary heart disease](https://scholariq.org/papers/serum-soluble-trem2-is-an-independent-biomarker-associated-with-coronary-heart/)
- [Triggering receptor expressed on myeloid cells 2 variants are rare in Parkinson's disease in a Han Chinese cohort](https://scholariq.org/papers/triggering-receptor-expressed-on-myeloid-cells-2-variants-are-rare-in-parkinson/)
- [Impact of Bioactive Compounds in the Management of Various InflammatoryDiseases](https://scholariq.org/papers/impact-of-bioactive-compounds-in-the-management-of-various-inflammatorydiseases/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
