# Ion Channels and Receptors
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/ion-channels-and-receptors/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the role of calcium signaling and ion channels, particularly TRP channels, in sensory neurons and their involvement in thermosensation, nociception, and the pain pathway. It also explores the function of store-operated channels, Orai1, and STIM1 in calcium homeostasis and signaling. The papers cover a wide range of topics related to calcium signaling in sensory perception and disease. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t11204 |
| Works | 82 |
## Topic papers all
Showing 15 of 82.
- [Calcium Channels, Stores, and Oscillations](https://scholariq.org/papers/calcium-channels-stores-and-oscillations/)
- [STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1](https://scholariq.org/papers/stim1-clusters-and-activates-crac-channels-via-direct-binding-of-a-cytosolic/)
- [Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis](https://scholariq.org/papers/randomized-controlled-trial-of-cannabis-based-medicine-in-central-pain-in/)
- [Role for protease activity in visceral pain in irritable bowel syndrome](https://scholariq.org/papers/role-for-protease-activity-in-visceral-pain-in-irritable-bowel-syndrome/)
- [Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23](https://scholariq.org/papers/usher-syndrome-1d-and-nonsyndromic-autosomal-recessive-deafness-dfnb12-are/)
- [Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice](https://scholariq.org/papers/increased-vascular-smooth-muscle-contractility-in-i-trpc6-i-sup-sup-sup-sup-sup/)
- [Systematic review of topical capsaicin for the treatment of chronic pain](https://scholariq.org/papers/systematic-review-of-topical-capsaicin-for-the-treatment-of-chronic-pain/)
- [Endocannabinoids control spasticity in a multiple sclerosis model](https://scholariq.org/papers/endocannabinoids-control-spasticity-in-a-multiple-sclerosis-model/)
- [Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain](https://scholariq.org/papers/selective-blockade-of-the-capsaicin-receptor-trpv1-attenuates-bone-cancer-pain/)
- [Gq‐coupled receptors as mechanosensors mediating myogenic vasoconstriction](https://scholariq.org/papers/gq-coupled-receptors-as-mechanosensors-mediating-myogenic-vasoconstriction/)
- [Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome](https://scholariq.org/papers/histamine-receptor-h1-mediated-sensitization-of-trpv1-mediates-visceral/)
- [Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1](https://scholariq.org/papers/decline-in-nrf2-regulated-antioxidants-in-chronic-obstructive-pulmonary-disease/)
- [Menthol: A refreshing look at this ancient compound](https://scholariq.org/papers/menthol-a-refreshing-look-at-this-ancient-compound/)
- [Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1](https://scholariq.org/papers/activation-of-the-trpc1-cation-channel-by-metabotropic-glutamate-receptor-mglur1/)
- [TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain](https://scholariq.org/papers/trpm8-is-the-principal-mediator-of-menthol-induced-analgesia-of-acute-and/)
## Topic primary papers
Showing 15 of 39.
- [STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1](https://scholariq.org/papers/stim1-clusters-and-activates-crac-channels-via-direct-binding-of-a-cytosolic/)
- [Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice](https://scholariq.org/papers/increased-vascular-smooth-muscle-contractility-in-i-trpc6-i-sup-sup-sup-sup-sup/)
- [Systematic review of topical capsaicin for the treatment of chronic pain](https://scholariq.org/papers/systematic-review-of-topical-capsaicin-for-the-treatment-of-chronic-pain/)
- [Gq‐coupled receptors as mechanosensors mediating myogenic vasoconstriction](https://scholariq.org/papers/gq-coupled-receptors-as-mechanosensors-mediating-myogenic-vasoconstriction/)
- [Menthol: A refreshing look at this ancient compound](https://scholariq.org/papers/menthol-a-refreshing-look-at-this-ancient-compound/)
- [TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain](https://scholariq.org/papers/trpm8-is-the-principal-mediator-of-menthol-induced-analgesia-of-acute-and/)
- [IP 3 Receptor Types 2 and 3 Mediate Exocrine Secretion Underlying Energy Metabolism](https://scholariq.org/papers/ip-sub-3-sub-receptor-types-2-and-3-mediate-exocrine-secretion-underlying-energy/)
- [Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1](https://scholariq.org/papers/pressure-induced-and-store-operated-cation-influx-in-vascular-smooth-muscle/)
- [Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia](https://scholariq.org/papers/gain-of-function-mutations-in-trpv4-cause-autosomal-dominant-brachyolmia/)
- [KCa and Ca2+ channels: The complex thought](https://scholariq.org/papers/kca-and-ca2-channels-the-complex-thought/)
- [Localized TRPA1 channel Ca 2+ signals stimulated by reactive oxygen species promote cerebral artery dilation](https://scholariq.org/papers/localized-trpa1-channel-ca-sup-2-sup-signals-stimulated-by-reactive-oxygen/)
- [Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti‐inflammatory effects of eucalyptol](https://scholariq.org/papers/transient-receptor-potential-cation-channel-subfamily-m-member-8-channels/)
- [Healthy Subjects Differentially Respond to Dietary Capsaicin Correlating with Specific Gut Enterotypes](https://scholariq.org/papers/healthy-subjects-differentially-respond-to-dietary-capsaicin-correlating-with/)
- [Brain endothelial cell TRPA1 channels initiate neurovascular coupling](https://scholariq.org/papers/brain-endothelial-cell-trpa1-channels-initiate-neurovascular-coupling/)
- [2-Aminoethoxydiphenyl borate (2-APB) inhibits capacitative calcium entry independently of the function of inositol 1,4,5-trisphosphate receptors.](https://scholariq.org/papers/2-aminoethoxydiphenyl-borate-2-apb-inhibits-capacitative-calcium-entry/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.