# Ion Transport and Channel Regulation
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/ion-transport-and-channel-regulation/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the molecular mechanisms, physiological roles, and pathophysiological implications of aquaporins, a family of water channel proteins involved in ion transport across cell membranes. The research covers various aspects such as brain edema, kidney function, regulation, and the role of aquaporins in disease. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10724 |
| Works | 226 |
## Topic papers all
Showing 15 of 226.
- [Molecular Mechanisms of Human Hypertension](https://scholariq.org/papers/molecular-mechanisms-of-human-hypertension/)
- [Chronic kidney disease](https://scholariq.org/papers/chronic-kidney-disease-2/)
- [De Novo Mutations in the Sodium-Channel Gene SCN1A Cause Severe Myoclonic Epilepsy of Infancy](https://scholariq.org/papers/de-novo-mutations-in-the-sodium-channel-gene-scn1a-cause-severe-myoclonic/)
- [Tolvaptan, a Selective Oral Vasopressin V 2 -Receptor Antagonist, for Hyponatremia](https://scholariq.org/papers/tolvaptan-a-selective-oral-vasopressin-v-sub-2-sub-receptor-antagonist-for/)
- [Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations](https://scholariq.org/papers/diagnosis-evaluation-and-treatment-of-hyponatremia-expert-panel-recommendations/)
- [A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract](https://scholariq.org/papers/a-case-for-interstitial-cells-of-cajal-as-pacemakers-and-mediators-of/)
- [Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III](https://scholariq.org/papers/mutations-in-the-chloride-channel-gene-clcnkb-cause-bartter-s-syndrome-type-iii/)
- [Clinical practice guideline on diagnosis and treatment of hyponatraemia](https://scholariq.org/papers/clinical-practice-guideline-on-diagnosis-and-treatment-of-hyponatraemia-3/)
- [Genetic heterogeneity of Barter's syndrome revealed by mutations in the K+ channel, ROMK](https://scholariq.org/papers/genetic-heterogeneity-of-barter-s-syndrome-revealed-by-mutations-in-the-k/)
- [A Single-Gene Cause in 29.5% of Cases of Steroid-Resistant Nephrotic Syndrome](https://scholariq.org/papers/a-single-gene-cause-in-29-5-of-cases-of-steroid-resistant-nephrotic-syndrome/)
- [The Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory](https://scholariq.org/papers/the-acid-activated-ion-channel-asic-contributes-to-synaptic-plasticity-learning/)
- [Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities](https://scholariq.org/papers/mutations-in-kelch-like-3-and-cullin-3-cause-hypertension-and-electrolyte/)
- [Remission of Proteinuria Improves Prognosis in IgA Nephropathy](https://scholariq.org/papers/remission-of-proteinuria-improves-prognosis-in-iga-nephropathy/)
- [Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism](https://scholariq.org/papers/somatic-and-germline-cacna1d-calcium-channel-mutations-in-aldosterone-producing/)
- [Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy](https://scholariq.org/papers/cellular-ph-regulators-potentially-promising-molecular-targets-for-cancer/)
## Topic primary papers
Showing 15 of 68.
- [Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III](https://scholariq.org/papers/mutations-in-the-chloride-channel-gene-clcnkb-cause-bartter-s-syndrome-type-iii/)
- [Genetic heterogeneity of Barter's syndrome revealed by mutations in the K+ channel, ROMK](https://scholariq.org/papers/genetic-heterogeneity-of-barter-s-syndrome-revealed-by-mutations-in-the-k/)
- [Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities](https://scholariq.org/papers/mutations-in-kelch-like-3-and-cullin-3-cause-hypertension-and-electrolyte/)
- [Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, and KCNJ10 Mutations](https://scholariq.org/papers/epilepsy-ataxia-sensorineural-deafness-tubulopathy-and-i-kcnj10-i-mutations/)
- [Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants](https://scholariq.org/papers/pharmacological-chaperones-rescue-cell-surface-expression-and-function-of/)
- [Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure](https://scholariq.org/papers/mutation-of-bsnd-causes-bartter-syndrome-with-sensorineural-deafness-and-kidney/)
- [Aquaporins in Brain: Distribution, Physiology, and Pathophysiology](https://scholariq.org/papers/aquaporins-in-brain-distribution-physiology-and-pathophysiology/)
- [Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney](https://scholariq.org/papers/gene-expression-levels-and-immunolocalization-of-organic-ion-transporters-in-the/)
- [Nephrogenic Diabetes Insipidus](https://scholariq.org/papers/nephrogenic-diabetes-insipidus/)
- [De novo mutations in ATP1A3 cause alternating hemiplegia of childhood](https://scholariq.org/papers/de-novo-mutations-in-atp1a3-cause-alternating-hemiplegia-of-childhood/)
- [Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference](https://scholariq.org/papers/gitelman-syndrome-consensus-and-guidance-from-a-kidney-disease-improving-global/)
- [KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron](https://scholariq.org/papers/klhl3-mutations-cause-familial-hyperkalemic-hypertension-by-impairing-ion/)
- [Molecular Pathogenesis of Pseudohypoaldosteronism Type II: Generation and Analysis of a Wnk4 Knockin Mouse Model](https://scholariq.org/papers/molecular-pathogenesis-of-pseudohypoaldosteronism-type-ii-generation-and/)
- [Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney](https://scholariq.org/papers/localization-of-the-extracellular-ca-sup-2-sup-polyvalent-cation-sensing-protein/)
- [Micropuncture studies on the filtration rate of single superficial and juxtamedullary glomeruli in the rat kidney](https://scholariq.org/papers/micropuncture-studies-on-the-filtration-rate-of-single-superficial-and/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.