# Kruppel-like factors research

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/kruppel-like-factors-research/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of Krüppel-like factors and other transcription factors in regulating gene expression, cell growth, and differentiation. It specifically focuses on their involvement in cancer, endothelial activation, proinflammatory signaling, and the maintenance of stem cells. Additionally, it delves into their impact on smooth muscle differentiation and their potential as tumor suppressors. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t13426 |
| Works | 122 |

## Topic papers all

Showing 15 of 122.

- [Genomewide Association Analysis of Coronary Artery Disease](https://scholariq.org/papers/genomewide-association-analysis-of-coronary-artery-disease/)
- [Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis](https://scholariq.org/papers/dll4-signalling-through-notch1-regulates-formation-of-tip-cells-during/)
- [Large-scale association analysis identifies new risk loci for coronary artery disease](https://scholariq.org/papers/large-scale-association-analysis-identifies-new-risk-loci-for-coronary-artery/)
- [Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.](https://scholariq.org/papers/disruption-of-the-cbfa2-gene-causes-necrosis-and-hemorrhaging-in-the-central/)
- [The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage](https://scholariq.org/papers/the-tyrosine-kinase-c-abl-regulates-p73-in-apoptotic-response-to-cisplatin/)
- [The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21](https://scholariq.org/papers/the-metabolic-state-of-diabetic-monkeys-is-regulated-by-fibroblast-growth-factor/)
- [Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor](https://scholariq.org/papers/identification-of-angiogenic-activity-and-the-cloning-and-expression-of-platelet/)
- [Haploinsufficiency of NSD1 causes Sotos syndrome](https://scholariq.org/papers/haploinsufficiency-of-nsd1-causes-sotos-syndrome/)
- [MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation](https://scholariq.org/papers/microrna-145-a-novel-smooth-muscle-cell-phenotypic-marker-and-modulator-controls/)
- [MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1](https://scholariq.org/papers/microrna-126-5p-promotes-endothelial-proliferation-and-limits-atherosclerosis-by/)
- [Exome-wide association study of plasma lipids in >300,000 individuals](https://scholariq.org/papers/exome-wide-association-study-of-plasma-lipids-in-and-gt-300-000-individuals/)
- [TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia](https://scholariq.org/papers/tgf-foxo-signalling-maintains-leukaemia-initiating-cells-in-chronic-myeloid/)
- [Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells](https://scholariq.org/papers/physiological-jak2v617f-expression-causes-a-lethal-myeloproliferative-neoplasm/)
- [Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke](https://scholariq.org/papers/src-deficiency-or-blockade-of-src-activity-in-mice-provides-cerebral-protection/)
- [Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I](https://scholariq.org/papers/efficacy-safety-and-survival-with-ruxolitinib-in-patients-with-myelofibrosis/)

## Topic primary papers

Showing 15 of 26.

- [MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1](https://scholariq.org/papers/microrna-126-5p-promotes-endothelial-proliferation-and-limits-atherosclerosis-by/)
- [Transcription Corepressor CtBP Is an NAD+-Regulated Dehydrogenase](https://scholariq.org/papers/transcription-corepressor-ctbp-is-an-nad-regulated-dehydrogenase/)
- [Correction: Corrigendum: Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4](https://scholariq.org/papers/correction-corrigendum-endothelial-dicer-promotes-atherosclerosis-and-vascular/)
- [Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer](https://scholariq.org/papers/acetylation-of-klf5-maintains-emt-and-tumorigenicity-to-cause-chemoresistant/)
- [CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling](https://scholariq.org/papers/ctbp-promotes-metastasis-of-breast-cancer-through-repressing-cholesterol-and/)
- [Transcription Factor KLF7 Is Important for Neuronal Morphogenesis in Selected Regions of the Nervous System](https://scholariq.org/papers/transcription-factor-klf7-is-important-for-neuronal-morphogenesis-in-selected/)
- [KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis](https://scholariq.org/papers/klf4-in-macrophages-attenuates-tnf-mediated-kidney-injury-and-fibrosis/)
- [MicroRNA-1 Regulates Smooth Muscle Cell Differentiation by Repressing Kruppel-Like Factor 4](https://scholariq.org/papers/microrna-1-regulates-smooth-muscle-cell-differentiation-by-repressing-kruppel/)
- [Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1](https://scholariq.org/papers/metabolic-reprogramming-regulates-the-proliferative-and-inflammatory-phenotype/)
- [A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine](https://scholariq.org/papers/a-genome-wide-association-study-identifies-susceptibility-loci-for-ossification/)
- [Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4](https://scholariq.org/papers/endothelial-dicer-promotes-atherosclerosis-and-vascular-inflammation-by-mirna/)
- [Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension](https://scholariq.org/papers/kruppel-like-factor-5-contributes-to-pulmonary-artery-smooth-muscle/)
- [KLF5 Activates MicroRNA 200 Transcription To Maintain Epithelial Characteristics and Prevent Induced Epithelial-Mesenchymal Transition in Epithelial Cells](https://scholariq.org/papers/klf5-activates-microrna-200-transcription-to-maintain-epithelial-characteristics/)
- [Krüppel-like Factor 4 Promotes Differentiation by Transforming Growth Factor-β Receptor-mediated Smad and p38 MAPK Signaling in Vascular Smooth Muscle Cells](https://scholariq.org/papers/kruppel-like-factor-4-promotes-differentiation-by-transforming-growth-factor/)
- [TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer](https://scholariq.org/papers/ttk-promotes-mesenchymal-signaling-via-multiple-mechanisms-in-triple-negative/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.