# Mechanisms of cancer metastasis

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/mechanisms-of-cancer-metastasis/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the molecular mechanisms and functions of metastasis suppressor genes, particularly the NDRG family, in regulating signal transduction, gene expression, cell proliferation, hypoxia response, epithelial-mesenchymal transition, and apoptosis in the context of cancer metastasis. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t13437 |
| Works | 33 |

## Topic papers all

Showing 15 of 33.

- [<i>ARID1A</i> Mutations in Endometriosis-Associated Ovarian Carcinomas](https://scholariq.org/papers/i-arid1a-i-mutations-in-endometriosis-associated-ovarian-carcinomas/)
- [Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells](https://scholariq.org/papers/reduced-tumor-incidence-metastatic-potential-and-cytokine-responsiveness-of-nm3/)
- [Identification of a second human nm23 gene, nm23-H2.](https://scholariq.org/papers/identification-of-a-second-human-nm23-gene-nm23-h2/)
- [Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.](https://scholariq.org/papers/transfection-of-human-nm23-h1-into-the-human-mda-mb-435-breast-carcinoma-cell/)
- [Phytochrome signalling is mediated through nucleoside diphosphate kinase 2](https://scholariq.org/papers/phytochrome-signalling-is-mediated-through-nucleoside-diphosphate-kinase-2/)
- [NHE3 Kinase A Regulatory Protein E3KARP Binds the Epithelial Brush Border Na+/H+ Exchanger NHE3 and the Cytoskeletal Protein Ezrin](https://scholariq.org/papers/nhe3-kinase-a-regulatory-protein-e3karp-binds-the-epithelial-brush-border-na-h/)
- [Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas.](https://scholariq.org/papers/evidence-for-nm23-rna-overexpression-dna-amplification-and-mutation-in/)
- [N-myc-dependent repression of Ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant](https://scholariq.org/papers/n-myc-dependent-repression-of-ndr1-a-gene-identified-by-direct-subtraction-of/)
- [KAI1 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases.](https://scholariq.org/papers/kai1-expression-is-up-regulated-in-early-pancreatic-cancer-and-decreased-in-the/)
- [Somatic allelic deletion of nm23 in human cancer.](https://scholariq.org/papers/somatic-allelic-deletion-of-nm23-in-human-cancer/)
- [Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma](https://scholariq.org/papers/association-of-nm23-h1-allelic-deletions-with-distant-metastases-in-colorectal/)
- [Non-small cell lung cancer with loss of expression of the SWI/SNF complex is associated with aggressive clinicopathological features, PD-L1-positive status, and high tumor mutation burden](https://scholariq.org/papers/non-small-cell-lung-cancer-with-loss-of-expression-of-the-swi-snf-complex-is/)
- [The effect of statins on risk and survival of gynecological malignancies](https://scholariq.org/papers/the-effect-of-statins-on-risk-and-survival-of-gynecological-malignancies/)
- [Kai1, A New Metastasis Suppressor Gene, Is Reduced in Metastatic Hepatocellular Carcinoma](https://scholariq.org/papers/kai1-a-new-metastasis-suppressor-gene-is-reduced-in-metastatic-hepatocellular/)
- [Nm23 and breast cancer metastasis](https://scholariq.org/papers/nm23-and-breast-cancer-metastasis/)

## Topic primary papers

- [Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells](https://scholariq.org/papers/reduced-tumor-incidence-metastatic-potential-and-cytokine-responsiveness-of-nm3/)
- [Identification of a second human nm23 gene, nm23-H2.](https://scholariq.org/papers/identification-of-a-second-human-nm23-gene-nm23-h2/)
- [Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.](https://scholariq.org/papers/transfection-of-human-nm23-h1-into-the-human-mda-mb-435-breast-carcinoma-cell/)
- [Phytochrome signalling is mediated through nucleoside diphosphate kinase 2](https://scholariq.org/papers/phytochrome-signalling-is-mediated-through-nucleoside-diphosphate-kinase-2/)
- [N-myc-dependent repression of Ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant](https://scholariq.org/papers/n-myc-dependent-repression-of-ndr1-a-gene-identified-by-direct-subtraction-of/)
- [KAI1 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases.](https://scholariq.org/papers/kai1-expression-is-up-regulated-in-early-pancreatic-cancer-and-decreased-in-the/)
- [Somatic allelic deletion of nm23 in human cancer.](https://scholariq.org/papers/somatic-allelic-deletion-of-nm23-in-human-cancer/)
- [Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma](https://scholariq.org/papers/association-of-nm23-h1-allelic-deletions-with-distant-metastases-in-colorectal/)
- [Kai1, A New Metastasis Suppressor Gene, Is Reduced in Metastatic Hepatocellular Carcinoma](https://scholariq.org/papers/kai1-a-new-metastasis-suppressor-gene-is-reduced-in-metastatic-hepatocellular/)
- [Nm23 and breast cancer metastasis](https://scholariq.org/papers/nm23-and-breast-cancer-metastasis/)
- [The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway](https://scholariq.org/papers/the-iron-chelator-dp44mt-inhibits-hepatocellular-carcinoma-metastasis-via-n-myc/)
- [POSSIBLE ASSOCIATION OF NM23 GENE-EXPRESSION AND KI-RAS POINT MUTATIONS WITH METASTATIC POTENTIAL IN HUMAN PANCREATIC CANCER-DERIVED CELL-LINES](https://scholariq.org/papers/possible-association-of-nm23-gene-expression-and-ki-ras-point-mutations-with/)
- [Relationship of serum levels of tumor markers with tissue expression of gene products in ovarian carcinoma.](https://scholariq.org/papers/relationship-of-serum-levels-of-tumor-markers-with-tissue-expression-of-gene/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.