# Metabolism, Diabetes, and Cancer

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/metabolism-diabetes-and-cancer-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 1,622,740 |
| Description | This cluster of papers explores the role of AMP-activated protein kinase (AMPK) in regulating cellular metabolism, including its involvement in glucose and lipid metabolism, insulin signaling, mitochondrial homeostasis, and the potential impact on cancer risk. The cluster also delves into the mechanisms of action of metformin, a drug known to activate AMPK and its effects on cellular energy balance and gene expression regulation. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T11339 |
| Works | 59,879 |

## Topic researchers

Showing 12 of 20.

- [Ahmedin Jemal](https://scholariq.org/researchers/ahmedin-jemal/)
- [Eric S. Lander](https://scholariq.org/researchers/eric-s-lander/)
- [Jacques Ferlay](https://scholariq.org/researchers/jacques-ferlay/)
- [Rob Knight](https://scholariq.org/researchers/rob-knight/)
- [George Davey Smith](https://scholariq.org/researchers/george-davey-smith/)
- [Ali H. Mokdad](https://scholariq.org/researchers/ali-h-mokdad/)
- [Walter C. Willett](https://scholariq.org/researchers/walter-c-willett/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Stacey Gabriel](https://scholariq.org/researchers/stacey-gabriel/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Bert Vogelstein](https://scholariq.org/researchers/bert-vogelstein/)
- [Gad Getz](https://scholariq.org/researchers/gad-getz/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.