# Metabolism, Diabetes, and Cancer **Type:** Topics **Canonical URL:** https://scholariq.org/topics/metabolism-diabetes-and-cancer/ ## Facts | Field | Value | | --- | --- | | Description | This cluster of papers explores the role of AMP-activated protein kinase (AMPK) in regulating cellular metabolism, including its involvement in glucose and lipid metabolism, insulin signaling, mitochondrial homeostasis, and the potential impact on cancer risk. The cluster also delves into the mechanisms of action of metformin, a drug known to activate AMPK and its effects on cellular energy balance and gene expression regulation. | | Domain | Life Sciences | | Field | Biochemistry, Genetics and Molecular Biology | | OpenAlex ID | t11339 | | Works | 499 | ## Topic papers all Showing 15 of 499. - [Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man](https://scholariq.org/papers/homeostasis-model-assessment-insulin-resistance-and-cell-function-from-fasting/) - [10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes](https://scholariq.org/papers/10-year-follow-up-of-intensive-glucose-control-in-type-2-diabetes/) - [Use and Abuse of HOMA Modeling](https://scholariq.org/papers/use-and-abuse-of-homa-modeling/) - [Once-Weekly Semaglutide in Adults with Overweight or Obesity](https://scholariq.org/papers/once-weekly-semaglutide-in-adults-with-overweight-or-obesity/) - [Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase](https://scholariq.org/papers/adiponectin-stimulates-glucose-utilization-and-fatty-acid-oxidation-by/) - [Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)](https://scholariq.org/papers/management-of-hyperglycaemia-in-type-2-diabetes-a-patient-centered-approach/) - [Glycemic index of foods: a physiological basis for carbohydrate exchange](https://scholariq.org/papers/glycemic-index-of-foods-a-physiological-basis-for-carbohydrate-exchange/) - [Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy](https://scholariq.org/papers/medical-management-of-hyperglycemia-in-type-2-diabetes-a-consensus-algorithm-for/) - [Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans](https://scholariq.org/papers/quantitative-insulin-sensitivity-check-index-a-simple-accurate-method-for/) - [Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers](https://scholariq.org/papers/inhibition-of-poly-adp-ribose-polymerase-in-tumors-from-i-brca-i-mutation/) - [Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach](https://scholariq.org/papers/management-of-hyperglycemia-in-type-2-diabetes-a-patient-centered-approach/) - [Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes](https://scholariq.org/papers/management-of-hyperglycemia-in-type-2-diabetes-2015-a-patient-centered-approach/) - [Prevalence of Diabetes among Men and Women in China](https://scholariq.org/papers/prevalence-of-diabetes-among-men-and-women-in-china/) - [Prediabetes: a high-risk state for diabetes development](https://scholariq.org/papers/prediabetes-a-high-risk-state-for-diabetes-development/) - [Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes](https://scholariq.org/papers/semaglutide-and-cardiovascular-outcomes-in-obesity-without-diabetes/) ## Topic primary papers Showing 15 of 113. - [Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man](https://scholariq.org/papers/homeostasis-model-assessment-insulin-resistance-and-cell-function-from-fasting/) - [Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase](https://scholariq.org/papers/adiponectin-stimulates-glucose-utilization-and-fatty-acid-oxidation-by/) - [Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism](https://scholariq.org/papers/oncogenic-kras-maintains-pancreatic-tumors-through-regulation-of-anabolic/) - [Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage](https://scholariq.org/papers/current-approaches-for-assessing-insulin-sensitivity-and-resistance-in-vivo/) - [Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein](https://scholariq.org/papers/structure-of-the-insulin-receptor-substrate-irs-1-defines-a-unique-signal/) - [Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene](https://scholariq.org/papers/alternative-pathway-of-insulin-signalling-in-mice-with-targeted-disruption-of/) - [Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor](https://scholariq.org/papers/insulin-stimulates-the-phosphorylation-of-the-95-000-dalton-subunit-of-its-own/) - [Mechanism by which metformin reduces glucose production in type 2 diabetes.](https://scholariq.org/papers/mechanism-by-which-metformin-reduces-glucose-production-in-type-2-diabetes/) - [Molecular Biology of Mammalian Glucose Transporters](https://scholariq.org/papers/molecular-biology-of-mammalian-glucose-transporters/) - [Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1](https://scholariq.org/papers/metformin-promotes-antitumor-immunity-via-endoplasmic-reticulum-associated/) - [Cancer Risk in Diabetic Patients Treated with Metformin: A Systematic Review and Meta-analysis](https://scholariq.org/papers/cancer-risk-in-diabetic-patients-treated-with-metformin-a-systematic-review-and/) - [The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism](https://scholariq.org/papers/the-lysosomal-v-atpase-ragulator-complex-is-a-common-activator-for-ampk-and/) - [Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance](https://scholariq.org/papers/identification-of-irs-1-ser-1101-as-a-target-of-s6k1-in-nutrient-and-obesity/) - [Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy](https://scholariq.org/papers/metformin-inhibits-the-nlrp3-inflammasome-via-ampk-mtor-dependent-effects-in/) - [Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders](https://scholariq.org/papers/metformin-and-cancer-risk-and-mortality-a-systematic-review-and-meta-analysis/) --- Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.