# Microbial Natural Products and Biosynthesis

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/microbial-natural-products-and-biosynthesis/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the exploration of natural products, particularly from microbial sources, as potential sources of new drugs. It covers various aspects such as genome sequencing, biosynthetic gene clusters, secondary metabolites, and their role in drug discovery. The cluster also emphasizes the significance of marine natural products and the potential of endophytic fungi in providing bioactive compounds for pharmaceutical applications. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10252 |
| Works | 66 |

## Topic papers all

Showing 15 of 66.

- [Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study](https://scholariq.org/papers/emergence-of-plasmid-mediated-colistin-resistance-mechanism-mcr-1-in-animals-and/)
- [Natural products in drug discovery: advances and opportunities](https://scholariq.org/papers/natural-products-in-drug-discovery-advances-and-opportunities/)
- [GMD@CSB.DB: the Golm Metabolome Database](https://scholariq.org/papers/gmd-csb-db-the-golm-metabolome-database/)
- [One Juliet and four Romeos: VeA and its methyltransferases](https://scholariq.org/papers/one-juliet-and-four-romeos-vea-and-its-methyltransferases/)
- [Fusion PCR and gene targeting in Aspergillus nidulans](https://scholariq.org/papers/fusion-pcr-and-gene-targeting-in-aspergillus-nidulans/)
- [Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast](https://scholariq.org/papers/exploring-the-mode-of-action-of-bioactive-compounds-by-chemical-genetic/)
- [Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice](https://scholariq.org/papers/discovery-of-a-small-molecule-insulin-mimetic-with-antidiabetic-activity-in-mice/)
- [Indole alkaloid biosynthesis in <i>Catharanthus roseus</i>: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase](https://scholariq.org/papers/indole-alkaloid-biosynthesis-in-i-catharanthus-roseus-i-new-enzyme-activities/)
- [Ustiloxins, antimitotic cydic peptides from false smut balls on rice panicles caused by Ustilaginoidea virens.](https://scholariq.org/papers/ustiloxins-antimitotic-cydic-peptides-from-false-smut-balls-on-rice-panicles/)
- [Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species](https://scholariq.org/papers/drivers-of-genetic-diversity-in-secondary-metabolic-gene-clusters-within-a/)
- [The Taxus genome provides insights into paclitaxel biosynthesis](https://scholariq.org/papers/the-taxus-genome-provides-insights-into-paclitaxel-biosynthesis/)
- [Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa](https://scholariq.org/papers/acquisition-of-16s-rrna-methylase-gene-in-pseudomonas-aeruginosa/)
- [Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold](https://scholariq.org/papers/refactoring-the-silent-spectinabilin-gene-cluster-using-a-plug-and-play-scaffold/)
- [Activation and identification of five clusters for secondary metabolites in <scp> <i>S</i> </scp> <i>treptomyces albus</i>   <scp>J</scp> 1074](https://scholariq.org/papers/activation-and-identification-of-five-clusters-for-secondary-metabolites-in-scp/)
- [Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi](https://scholariq.org/papers/fusicoccins-are-biosynthesized-by-an-unusual-chimera-diterpene-synthase-in-fungi/)

## Topic primary papers

Showing 15 of 32.

- [Natural products in drug discovery: advances and opportunities](https://scholariq.org/papers/natural-products-in-drug-discovery-advances-and-opportunities/)
- [One Juliet and four Romeos: VeA and its methyltransferases](https://scholariq.org/papers/one-juliet-and-four-romeos-vea-and-its-methyltransferases/)
- [Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast](https://scholariq.org/papers/exploring-the-mode-of-action-of-bioactive-compounds-by-chemical-genetic/)
- [Ustiloxins, antimitotic cydic peptides from false smut balls on rice panicles caused by Ustilaginoidea virens.](https://scholariq.org/papers/ustiloxins-antimitotic-cydic-peptides-from-false-smut-balls-on-rice-panicles/)
- [Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species](https://scholariq.org/papers/drivers-of-genetic-diversity-in-secondary-metabolic-gene-clusters-within-a/)
- [Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold](https://scholariq.org/papers/refactoring-the-silent-spectinabilin-gene-cluster-using-a-plug-and-play-scaffold/)
- [Activation and identification of five clusters for secondary metabolites in <scp> <i>S</i> </scp> <i>treptomyces albus</i>   <scp>J</scp> 1074](https://scholariq.org/papers/activation-and-identification-of-five-clusters-for-secondary-metabolites-in-scp/)
- [Prototype of an intertwined secondary-metabolite supercluster](https://scholariq.org/papers/prototype-of-an-intertwined-secondary-metabolite-supercluster/)
- [A scalable platform to identify fungal secondary metabolites and their gene clusters](https://scholariq.org/papers/a-scalable-platform-to-identify-fungal-secondary-metabolites-and-their-gene/)
- [The Isolation of Three New Crystalline Antibiotics from Streptomyces<sup>1</sup>](https://scholariq.org/papers/the-isolation-of-three-new-crystalline-antibiotics-from-streptomyces-sup-1-sup/)
- [Endophytic Fungi: Biodiversity, Ecological Significance, and Potential Industrial Applications](https://scholariq.org/papers/endophytic-fungi-biodiversity-ecological-significance-and-potential-industrial/)
- [Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi](https://scholariq.org/papers/structural-diversity-and-biological-activities-of-cyclic-depsipeptides-from/)
- [Phase I and Pharmacokinetic Study of Aplidine, a New Marine Cyclodepsipeptide in Patients With Advanced Malignancies](https://scholariq.org/papers/phase-i-and-pharmacokinetic-study-of-aplidine-a-new-marine-cyclodepsipeptide-in/)
- [Distribution and identification of actinomycetes lysing cyanobacteria in a eutrophic lake](https://scholariq.org/papers/distribution-and-identification-of-actinomycetes-lysing-cyanobacteria-in-a/)
- [Structural basis for the biosynthesis of lovastatin](https://scholariq.org/papers/structural-basis-for-the-biosynthesis-of-lovastatin/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
