# Microtubule and mitosis dynamics
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/microtubule-and-mitosis-dynamics/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the regulation and function of microtubules in cell division, with a focus on topics such as mitotic checkpoint, molecular motors, aneuploidy, and the role of kinesin proteins and Aurora kinases. It also delves into the implications of chromosomal instability and the potential applications for cancer therapy. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10492 |
| Works | 156 |
## Topic papers all
Showing 15 of 156.
- [The Amber biomolecular simulation programs](https://scholariq.org/papers/the-amber-biomolecular-simulation-programs/)
- [Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase](https://scholariq.org/papers/signaling-from-rho-to-the-actin-cytoskeleton-through-protein-kinases-rock-and/)
- [ATR disruption leads to chromosomal fragmentation and early embryonic lethality](https://scholariq.org/papers/i-atr-i-disruption-leads-to-chromosomal-fragmentation-and-early-embryonic/)
- [Locoregional cancer treatment with magnetic drug targeting.](https://scholariq.org/papers/locoregional-cancer-treatment-with-magnetic-drug-targeting/)
- [Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma](https://scholariq.org/papers/transforming-fusions-of-i-fgfr-i-and-i-tacc-i-genes-in-human-glioblastoma/)
- [Gene Expression Signature of Cigarette Smoking and Its Role in Lung Adenocarcinoma Development and Survival](https://scholariq.org/papers/gene-expression-signature-of-cigarette-smoking-and-its-role-in-lung/)
- [The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest](https://scholariq.org/papers/the-retinoblastoma-protein-and-brg1-form-a-complex-and-cooperate-to-induce-cell/)
- [KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria](https://scholariq.org/papers/kif1b-a-novel-microtubule-plus-end-directed-monomeric-motor-protein-for/)
- [Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage](https://scholariq.org/papers/inhibition-of-human-chk1-causes-increased-initiation-of-dna-replication/)
- [A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity](https://scholariq.org/papers/a-spatial-model-predicts-that-dispersal-and-cell-turnover-limit-intratumour/)
- [PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats](https://scholariq.org/papers/pkhd1-the-polycystic-kidney-and-hepatic-disease-1-gene-encodes-a-novel-large/)
- [Single-Molecule Speckle Analysis of Actin Filament Turnover in Lamellipodia](https://scholariq.org/papers/single-molecule-speckle-analysis-of-actin-filament-turnover-in-lamellipodia/)
- [Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly](https://scholariq.org/papers/mutations-in-tubg1-dync1h1-kif5c-and-kif2a-cause-malformations-of-cortical/)
- [Synapse formation between central neurons requires postsynaptic expression of the MEN1 tumor suppressor gene.](https://scholariq.org/papers/synapse-formation-between-central-neurons-requires-postsynaptic-expression-of/)
- [Molecular Dissection of the Rho-associated Protein Kinase (p160ROCK)-regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells](https://scholariq.org/papers/molecular-dissection-of-the-rho-associated-protein-kinase-p160rock-regulated/)
## Topic primary papers
Showing 15 of 33.
- [KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria](https://scholariq.org/papers/kif1b-a-novel-microtubule-plus-end-directed-monomeric-motor-protein-for/)
- [Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly](https://scholariq.org/papers/mutations-in-tubg1-dync1h1-kif5c-and-kif2a-cause-malformations-of-cortical/)
- [Microtubule-associated protein tau: A marker of paclitaxel sensitivity in breast cancer](https://scholariq.org/papers/microtubule-associated-protein-tau-a-marker-of-paclitaxel-sensitivity-in-breast/)
- [Slippage of Mitotic Arrest and Enhanced Tumor Development in Mice with BubR1 Haploinsufficiency](https://scholariq.org/papers/slippage-of-mitotic-arrest-and-enhanced-tumor-development-in-mice-with-b-i-bubr1/)
- [DYX1C1 is required for axonemal dynein assembly and ciliary motility](https://scholariq.org/papers/dyx1c1-is-required-for-axonemal-dynein-assembly-and-ciliary-motility/)
- [AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo](https://scholariq.org/papers/azd1152-a-novel-and-selective-aurora-b-kinase-inhibitor-induces-growth-arrest/)
- [A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma](https://scholariq.org/papers/a-novel-aurora-a-kinase-inhibitor-mln8237-induces-cytotoxicity-and-cell-cycle/)
- [Overexpression of KIF23 predicts clinical outcome in primary lung cancer patients](https://scholariq.org/papers/overexpression-of-kif23-predicts-clinical-outcome-in-primary-lung-cancer/)
- [The Roles of Fission Yeast Ase1 in Mitotic Cell Division, Meiotic Nuclear Oscillation, and Cytokinesis Checkpoint Signaling](https://scholariq.org/papers/the-roles-of-fission-yeast-ase1-in-mitotic-cell-division-meiotic-nuclear/)
- [AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients](https://scholariq.org/papers/aurka-dlgap5-tpx2-kif11-and-ckap5-five-specific-mitosis-associated-genes/)
- [PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway](https://scholariq.org/papers/prc1-contributes-to-tumorigenesis-of-lung-adenocarcinoma-in-association-with-the/)
- [Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models](https://scholariq.org/papers/cre-loxp-controlled-periodic-aurora-a-overexpression-induces-mitotic/)
- [Localization of a mammalian homolog of diaphanous, mDia1, to the mitotic spindle in HeLa cells](https://scholariq.org/papers/localization-of-a-mammalian-homolog-of-diaphanous-mdia1-to-the-mitotic-spindle/)
- [Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the γTuRC to the centrosome](https://scholariq.org/papers/sequential-phosphorylation-of-nedd1-by-cdk1-and-plk1-is-required-for-targeting/)
- [Evidence for tubulin-binding sites on cellular membranes: plasma membranes, mitochondrial membranes, and secretory granule membranes.](https://scholariq.org/papers/evidence-for-tubulin-binding-sites-on-cellular-membranes-plasma-membranes/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.