# Natural product bioactivities and synthesis

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/natural-product-bioactivities-and-synthesis/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the biological activities, pharmacological properties, and potential therapeutic implications of triterpenoids and saponins, with a focus on their anti-cancer, anti-inflammatory, antioxidant, and antiviral properties. The research also delves into the use of saponins as adjuvants in vaccines and their effects on immune responses. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11385 |
| Works | 121 |

## Topic papers all

Showing 15 of 121.

- [Bioactive flavonoids in medicinal plants: Structure, activity and biological fate](https://scholariq.org/papers/bioactive-flavonoids-in-medicinal-plants-structure-activity-and-biological-fate/)
- [Redox Regulation of NF-kappa B Activation](https://scholariq.org/papers/redox-regulation-of-nf-kappa-b-activation/)
- [Review of the Botanical Characteristics, Phytochemistry, and Pharmacology of <scp><i>Astragalus membranaceus</i></scp> (Huangqi)](https://scholariq.org/papers/review-of-the-botanical-characteristics-phytochemistry-and-pharmacology-of-scp-i/)
- [Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity](https://scholariq.org/papers/flavones-food-sources-bioavailability-metabolism-and-bioactivity/)
- [Dietary Flavonoid Aglycones and Their Glycosides: Which Show Better Biological Significance?](https://scholariq.org/papers/dietary-flavonoid-aglycones-and-their-glycosides-which-show-better-biological/)
- [Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils](https://scholariq.org/papers/anti-inflammatory-activity-of-linalool-and-linalyl-acetate-constituents-of/)
- [Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis](https://scholariq.org/papers/enzymes-of-the-cyclooxygenase-pathways-of-prostanoid-biosynthesis/)
- [Phase IIa Clinical Trial of Curcumin for the Prevention of Colorectal Neoplasia](https://scholariq.org/papers/phase-iia-clinical-trial-of-curcumin-for-the-prevention-of-colorectal-neoplasia/)
- [Phytol: A review of biomedical activities](https://scholariq.org/papers/phytol-a-review-of-biomedical-activities/)
- [Advance on the Flavonoid<i>C</i>-glycosides and Health Benefits](https://scholariq.org/papers/advance-on-the-flavonoid-i-c-i-glycosides-and-health-benefits/)
- [Anthocyanins Inhibit Nuclear Factor-κB Activation in Monocytes and Reduce Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults , ,3](https://scholariq.org/papers/anthocyanins-inhibit-nuclear-factor-b-activation-in-monocytes-and-reduce-plasma/)
- [Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng](https://scholariq.org/papers/antioxidant-and-anti-tumor-promoting-activities-of-the-methanol-extract-of-heat/)
- [Apigenin Blocks Lipopolysaccharide-Induced Lethality In Vivo and Proinflammatory Cytokines Expression by Inactivating NF-κB through the Suppression of p65 Phosphorylation](https://scholariq.org/papers/apigenin-blocks-lipopolysaccharide-induced-lethality-in-vivo-and-proinflammatory/)
- [Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity](https://scholariq.org/papers/cellular-uptake-and-metabolism-of-flavonoids-and-their-metabolites-implications/)
- [Five <i>Pistacia</i> species (<i>P. vera</i>, <i>P. atlantica</i>, <i>P. terebinthus</i>, <i>P. khinjuk</i>, and <i>P. lentiscus</i>): A Review of Their Traditional Uses, Phytochemistry, and Pharmacology](https://scholariq.org/papers/five-i-pistacia-i-species-i-p-vera-i-i-p-atlantica-i-i-p-terebinthus-i-i-p/)

## Topic primary papers

Showing 15 of 25.

- [Targeting NF-κB signaling pathway in cancer by dietary polyphenols](https://scholariq.org/papers/targeting-nf-b-signaling-pathway-in-cancer-by-dietary-polyphenols/)
- [Acute anti-inflammatory activity of four saponins isolated from ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F in carrageenan-induced rat paw edema](https://scholariq.org/papers/acute-anti-inflammatory-activity-of-four-saponins-isolated-from-ivy-alpha/)
- [Botany, traditional uses, phytochemistry, analytical methods, processing, pharmacology and pharmacokinetics of Bupleuri Radix: A systematic review](https://scholariq.org/papers/botany-traditional-uses-phytochemistry-analytical-methods-processing/)
- [Triterpenoid Saponins from Stauntonia chinensis Ameliorate Insulin Resistance via the AMP-Activated Protein Kinase and IR/IRS-1/PI3K/Akt Pathways in Insulin-Resistant HepG2 Cells](https://scholariq.org/papers/triterpenoid-saponins-from-stauntonia-chinensis-ameliorate-insulin-resistance/)
- [Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway](https://scholariq.org/papers/saikosaponin-a-improved-depression-like-behavior-and-inhibited-hippocampal/)
- [Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer](https://scholariq.org/papers/betulinic-acid-targets-yy1-and-erbb2-through-cannabinoid-receptor-dependent/)
- [Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease](https://scholariq.org/papers/inhibition-of-12-15-lipoxygenase-by-baicalein-induces-microglia-ppar-a-potential/)
- [The importance of natural product characterization in studies of their anti‐inflammatory activity](https://scholariq.org/papers/the-importance-of-natural-product-characterization-in-studies-of-their-anti/)
- [Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke](https://scholariq.org/papers/ruscogenin-reduces-cerebral-ischemic-injury-via-nf-b-mediated-inflammatory/)
- [Pharmacological effects of the isomeric mixture of alpha and beta amyrin from <i>Protium heptaphyllum</i>: a literature review](https://scholariq.org/papers/pharmacological-effects-of-the-isomeric-mixture-of-alpha-and-beta-amyrin-from-i/)
- [Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth](https://scholariq.org/papers/betulinic-acid-decreases-specificity-protein-1-sp1-level-via-increasing-the/)
- [Carnosic acid (CA) attenuates collagen-induced arthritis in db/db mice via inflammation suppression by regulating ROS-dependent p38 pathway](https://scholariq.org/papers/carnosic-acid-ca-attenuates-collagen-induced-arthritis-in-db-db-mice-via/)
- [The anticancer effect and mechanism of α-hederin on breast cancer cells](https://scholariq.org/papers/the-anticancer-effect-and-mechanism-of-hederin-on-breast-cancer-cells/)
- [Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells](https://scholariq.org/papers/ursolic-acid-induces-cell-cycle-arrest-and-apoptosis-of-gallbladder-carcinoma/)
- [Analgesic and Anti-Inflammatory Activities of the Isomeric Mixture of Alpha- and Beta-Amyrin from Protium heptaphyllum(Aubl.) March](https://scholariq.org/papers/analgesic-and-anti-inflammatory-activities-of-the-isomeric-mixture-of-alpha-and/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
