# Nephrotoxicity and Medicinal Plants

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/nephrotoxicity-and-medicinal-plants/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the health effects associated with aristolochic acid, a compound found in certain Chinese herbs, and its link to nephropathy, urothelial carcinoma, and acute interstitial nephritis. It explores the renal toxicity, mutation signatures, DNA adduct formation, and the potential carcinogenicity of aristolochic acid in herbal remedies. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t12962 |
| Works | 93 |

## Topic papers all

Showing 15 of 93.

- [Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage](https://scholariq.org/papers/tubulointerstitial-changes-as-a-major-determinant-in-the-progression-of-renal/)
- [Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease](https://scholariq.org/papers/proton-pump-inhibitor-use-and-the-risk-of-chronic-kidney-disease/)
- [Review of the Botanical Characteristics, Phytochemistry, and Pharmacology of <scp><i>Astragalus membranaceus</i></scp> (Huangqi)](https://scholariq.org/papers/review-of-the-botanical-characteristics-phytochemistry-and-pharmacology-of-scp-i/)
- [Herb-Drug Interactions](https://scholariq.org/papers/herb-drug-interactions/)
- [Aristolochic acid and the etiology of endemic (Balkan) nephropathy](https://scholariq.org/papers/aristolochic-acid-and-the-etiology-of-endemic-balkan-nephropathy/)
- [Acute kidney injury in China: a cross-sectional survey](https://scholariq.org/papers/acute-kidney-injury-in-china-a-cross-sectional-survey/)
- [Multitarget Therapy for Induction Treatment of Lupus Nephritis](https://scholariq.org/papers/multitarget-therapy-for-induction-treatment-of-lupus-nephritis/)
- [Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults](https://scholariq.org/papers/epidemiology-and-clinical-correlates-of-aki-in-chinese-hospitalized-adults/)
- [Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy](https://scholariq.org/papers/effect-of-oral-methylprednisolone-on-decline-in-kidney-function-or-kidney/)
- [Garlic and Cancer: A Critical Review of the Epidemiologic Literature](https://scholariq.org/papers/garlic-and-cancer-a-critical-review-of-the-epidemiologic-literature/)
- [Novel Acquired Metallo-β-Lactamase Gene,<i>bla</i><sub>SIM-1</sub>, in a Class 1 Integron from<i>Acinetobacter baumannii</i>Clinical Isolates from Korea](https://scholariq.org/papers/novel-acquired-metallo-lactamase-gene-i-bla-i-sub-sim-1-sub-in-a-class-1/)
- [The Modern Spectrum of Renal Biopsy Findings in Patients with Diabetes](https://scholariq.org/papers/the-modern-spectrum-of-renal-biopsy-findings-in-patients-with-diabetes/)
- [Efficacy and safety of a targeted-release formulation of budesonide in patients with primary IgA nephropathy (NefIgArd): 2-year results from a randomised phase 3 trial](https://scholariq.org/papers/efficacy-and-safety-of-a-targeted-release-formulation-of-budesonide-in-patients/)
- [Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk](https://scholariq.org/papers/population-based-case-control-study-of-chinese-herbal-products-containing/)
- [Effects of Hydroxychloroquine on Proteinuria in IgA Nephropathy: A Randomized Controlled Trial](https://scholariq.org/papers/effects-of-hydroxychloroquine-on-proteinuria-in-iga-nephropathy-a-randomized/)

## Topic primary papers

Showing 15 of 27.

- [Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage](https://scholariq.org/papers/tubulointerstitial-changes-as-a-major-determinant-in-the-progression-of-renal/)
- [Herb-Drug Interactions](https://scholariq.org/papers/herb-drug-interactions/)
- [Aristolochic acid and the etiology of endemic (Balkan) nephropathy](https://scholariq.org/papers/aristolochic-acid-and-the-etiology-of-endemic-balkan-nephropathy/)
- [Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk](https://scholariq.org/papers/population-based-case-control-study-of-chinese-herbal-products-containing/)
- [Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation](https://scholariq.org/papers/aristolochic-acid-induces-proximal-tubule-apoptosis-and-epithelial-to/)
- [Duration of Treatment with Corticosteroids and Recovery of Kidney Function in Acute Interstitial Nephritis](https://scholariq.org/papers/duration-of-treatment-with-corticosteroids-and-recovery-of-kidney-function-in/)
- [Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies](https://scholariq.org/papers/early-proximal-tubule-injury-in-experimental-aristolochic-acid-nephropathy/)
- [Molecular Structure and Phylogenetic Analyses of Complete Chloroplast Genomes of Two Aristolochia Medicinal Species](https://scholariq.org/papers/molecular-structure-and-phylogenetic-analyses-of-complete-chloroplast-genomes-of/)
- [Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy](https://scholariq.org/papers/exceptionally-long-term-persistence-of-dna-adducts-formed-by-carcinogenic/)
- [A Study of the Antioxidative and Antimutagenic Effects of Houttuynia cordata Thunb. Using an Oxidized Frying Oil-Fed Model](https://scholariq.org/papers/a-study-of-the-antioxidative-and-antimutagenic-effects-of-houttuynia-cordata/)
- [Houttuynia cordata blocks HSV infection through inhibition of NF-κB activation](https://scholariq.org/papers/houttuynia-cordata-blocks-hsv-infection-through-inhibition-of-nf-b-activation/)
- [Patterns of interstitial inflammation during the evolution of renal injury in experimental aristolochic acid nephropathy](https://scholariq.org/papers/patterns-of-interstitial-inflammation-during-the-evolution-of-renal-injury-in/)
- [Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway](https://scholariq.org/papers/bardoxolone-methyl-bard-ameliorates-aristolochic-acid-aa-induced-acute-kidney/)
- [Acute tubulointerstitial nephritis in Scotland](https://scholariq.org/papers/acute-tubulointerstitial-nephritis-in-scotland/)
- [Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis](https://scholariq.org/papers/identification-and-validation-of-urinary-cxcl9-as-a-biomarker-for-diagnosis-of/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
