# Nerve injury and regeneration

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/nerve-injury-and-regeneration/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the roles of neurotrophins, particularly BDNF and GDNF, in neuronal development, synaptic modulation, nerve regeneration, and their implications for conditions such as depression and spinal cord injury. It covers topics such as neurotrophin signaling pathways, axon regeneration, synaptic plasticity, and the impact of neurotrophins on mood disorders. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t10483 |
| Works | 243 |

## Topic papers all

Showing 15 of 243.

- [Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation](https://scholariq.org/papers/lewy-bodies-in-grafted-neurons-in-subjects-with-parkinson-s-disease-suggest-host/)
- [-Synuclein in Parkinson's Disease](https://scholariq.org/papers/synuclein-in-parkinson-s-disease/)
- [Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease](https://scholariq.org/papers/transneuronal-propagation-of-pathologic-synuclein-from-the-gut-to-the-brain/)
- [Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67‐GFP knock‐in mouse](https://scholariq.org/papers/green-fluorescent-protein-expression-and-colocalization-with-calretinin/)
- [Neurodegeneration Prevented by Lentiviral Vector Delivery of GDNF in Primate Models of Parkinson's Disease](https://scholariq.org/papers/neurodegeneration-prevented-by-lentiviral-vector-delivery-of-gdnf-in-primate/)
- [Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants](https://scholariq.org/papers/alterations-of-serum-levels-of-brain-derived-neurotrophic-factor-bdnf-in/)
- [Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival](https://scholariq.org/papers/cell-produced-synuclein-is-secreted-in-a-calcium-dependent-manner-by-exosomes/)
- [Randomized controlled trial of intraputamenal glial cell line–derived neurotrophic factor infusion in Parkinson disease](https://scholariq.org/papers/randomized-controlled-trial-of-intraputamenal-glial-cell-line-derived/)
- [Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum](https://scholariq.org/papers/single-nigrostriatal-dopaminergic-neurons-form-widely-spread-and-highly-dense/)
- [Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD](https://scholariq.org/papers/randomized-double-blind-trial-of-glial-cell-line-derived-neurotrophic-factor/)
- [Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease](https://scholariq.org/papers/minocycline-prevents-nigrostriatal-dopaminergic-neurodegeneration-in-the-mptp/)
- [Spinal cord injury: molecular mechanisms and therapeutic interventions](https://scholariq.org/papers/spinal-cord-injury-molecular-mechanisms-and-therapeutic-interventions/)
- [Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease](https://scholariq.org/papers/intranasal-delivery-bypasses-the-blood-brain-barrier-to-target-therapeutic/)
- [AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial](https://scholariq.org/papers/aav2-gad-gene-therapy-for-advanced-parkinson-s-disease-a-double-blind-sham/)
- [Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells](https://scholariq.org/papers/wild-type-synuclein-is-degraded-by-chaperone-mediated-autophagy-and/)

## Topic primary papers

Showing 15 of 95.

- [Neurodegeneration Prevented by Lentiviral Vector Delivery of GDNF in Primate Models of Parkinson's Disease](https://scholariq.org/papers/neurodegeneration-prevented-by-lentiviral-vector-delivery-of-gdnf-in-primate/)
- [Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants](https://scholariq.org/papers/alterations-of-serum-levels-of-brain-derived-neurotrophic-factor-bdnf-in/)
- [Randomized controlled trial of intraputamenal glial cell line–derived neurotrophic factor infusion in Parkinson disease](https://scholariq.org/papers/randomized-controlled-trial-of-intraputamenal-glial-cell-line-derived/)
- [Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD](https://scholariq.org/papers/randomized-double-blind-trial-of-glial-cell-line-derived-neurotrophic-factor/)
- [Brain-Derived Neurotrophic Factor Is Associated with Age-Related Decline in Hippocampal Volume](https://scholariq.org/papers/brain-derived-neurotrophic-factor-is-associated-with-age-related-decline-in/)
- [Critical role of brain-derived neurotrophic factor in mood disorders](https://scholariq.org/papers/critical-role-of-brain-derived-neurotrophic-factor-in-mood-disorders/)
- [Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (<i>BDNF</i>) Gene](https://scholariq.org/papers/hyperphagia-severe-obesity-impaired-cognitive-function-and-hyperactivity/)
- [Controlled release of nerve growth factor enhances sciatic nerve regeneration](https://scholariq.org/papers/controlled-release-of-nerve-growth-factor-enhances-sciatic-nerve-regeneration/)
- [Mechanisms of acute axonal degeneration in the optic nerve in vivo](https://scholariq.org/papers/mechanisms-of-acute-axonal-degeneration-in-the-optic-nerve-in-vivo/)
- [Axon Branch Removal at Developing Synapses by Axosome Shedding](https://scholariq.org/papers/axon-branch-removal-at-developing-synapses-by-axosome-shedding/)
- [Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder](https://scholariq.org/papers/decreased-serum-levels-of-mature-brain-derived-neurotrophic-factor-bdnf-but-not/)
- [Minocycline Alleviates Death of Oligodendrocytes by Inhibiting Pro-Nerve Growth Factor Production in Microglia after Spinal Cord Injury](https://scholariq.org/papers/minocycline-alleviates-death-of-oligodendrocytes-by-inhibiting-pro-nerve-growth/)
- [Effects of motor versus sensory nerve grafts on peripheral nerve regeneration](https://scholariq.org/papers/effects-of-motor-versus-sensory-nerve-grafts-on-peripheral-nerve-regeneration/)
- [Role of macrophages in peripheral nerve injury and repair](https://scholariq.org/papers/role-of-macrophages-in-peripheral-nerve-injury-and-repair/)
- [The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression](https://scholariq.org/papers/the-val66met-polymorphism-of-the-brain-derived-neurotrophic-factor-gene-is/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.