# Nuclear Receptors and Signaling
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/nuclear-receptors-and-signaling/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t13991 |
| Works | 122 |
## Topic papers all
Showing 15 of 122.
- [Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism](https://scholariq.org/papers/mutations-in-the-i-dj-1-i-gene-associated-with-autosomal-recessive-early-onset/)
- [Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030](https://scholariq.org/papers/projected-number-of-people-with-parkinson-disease-in-the-most-populous-nations/)
- [The Parkinson Progression Marker Initiative (PPMI)](https://scholariq.org/papers/the-parkinson-progression-marker-initiative-ppmi/)
- [Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation](https://scholariq.org/papers/lewy-bodies-in-grafted-neurons-in-subjects-with-parkinson-s-disease-suggest-host/)
- [Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin](https://scholariq.org/papers/mitochondrial-dysfunction-in-drosophila-pink1-mutants-is-complemented-by-parkin/)
- [-Synuclein in Parkinson's Disease](https://scholariq.org/papers/synuclein-in-parkinson-s-disease/)
- [PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease](https://scholariq.org/papers/i-pgc-1-i-a-potential-therapeutic-target-for-early-intervention-in-parkinson-s/)
- [Parkinson Disease in Twins](https://scholariq.org/papers/parkinson-disease-in-twins/)
- [Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss](https://scholariq.org/papers/deletion-of-the-developmentally-essential-gene-atr-in-adult-mice-leads-to-age/)
- [The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort](https://scholariq.org/papers/the-parkinson-s-progression-markers-initiative-ppmi-establishing-a-pd-biomarker/)
- [Serum Total Cholesterol, Apolipoprotein E {FC12}e4 Allele, and Alzheimer’s Disease](https://scholariq.org/papers/serum-total-cholesterol-apolipoprotein-e-fc12-e4-allele-and-alzheimer-s-disease/)
- [Multiple sclerosis progression: time for a new mechanism-driven framework](https://scholariq.org/papers/multiple-sclerosis-progression-time-for-a-new-mechanism-driven-framework/)
- [Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells](https://scholariq.org/papers/drug-screening-for-als-using-patient-specific-induced-pluripotent-stem-cells/)
- [Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene](https://scholariq.org/papers/hyperphagia-severe-obesity-impaired-cognitive-function-and-hyperactivity/)
- [Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector](https://scholariq.org/papers/gain-of-toxic-apolipoprotein-e4-effects-in-human-ipsc-derived-neurons-is/)
## Topic primary papers
Showing 15 of 22.
- [Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss](https://scholariq.org/papers/deletion-of-the-developmentally-essential-gene-atr-in-adult-mice-leads-to-age/)
- [Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q](https://scholariq.org/papers/pathologic-and-biochemical-studies-of-juvenile-parkinsonism-linked-to-chromosome/)
- [High-level expression of Egr-1 and Egr-1–inducible genes in mouse and human atherosclerosis](https://scholariq.org/papers/high-level-expression-of-egr-1-and-egr-1-inducible-genes-in-mouse-and-human/)
- [RETRACTED ARTICLE: NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α](https://scholariq.org/papers/retracted-article-nr4a1-aggravates-the-cardiac-microvascular-ischemia/)
- [Activation and Induction of NUR77/NURR1 in Corticotrophs by CRH/cAMP: Involvement of Calcium, Protein Kinase A, and MAPK Pathways](https://scholariq.org/papers/activation-and-induction-of-nur77-nurr1-in-corticotrophs-by-crh-camp-involvement/)
- [ERK5 Is a Novel Type of Mitogen-Activated Protein Kinase Containing a Transcriptional Activation Domain](https://scholariq.org/papers/erk5-is-a-novel-type-of-mitogen-activated-protein-kinase-containing-a/)
- [Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway](https://scholariq.org/papers/orphan-nuclear-receptor-tr3-acts-in-autophagic-cell-death-via-mitochondrial/)
- [Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice](https://scholariq.org/papers/rapamycin-attenuates-the-progression-of-tau-pathology-in-p301s-tau-transgenic/)
- [Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease](https://scholariq.org/papers/transcriptional-repression-of-p53-by-parkin-and-impairment-by-mutations/)
- [Molecular Pathways: The Role of NR4A Orphan Nuclear Receptors in Cancer](https://scholariq.org/papers/molecular-pathways-the-role-of-nr4a-orphan-nuclear-receptors-in-cancer/)
- [DNA-PKcs promotes alcohol-related liver disease by activating Drp1-related mitochondrial fission and repressing FUNDC1-required mitophagy](https://scholariq.org/papers/dna-pkcs-promotes-alcohol-related-liver-disease-by-activating-drp1-related/)
- [The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK](https://scholariq.org/papers/the-orphan-nuclear-receptor-nur77-regulates-lkb1-localization-and-activates-ampk/)
- [BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.](https://scholariq.org/papers/bmx-a-novel-nonreceptor-tyrosine-kinase-gene-of-the-btk-itk-tec-txk-family/)
- [Orphan nuclear receptor TR3/Nur77 regulates VEGF-A–induced angiogenesis through its transcriptional activity](https://scholariq.org/papers/orphan-nuclear-receptor-tr3-nur77-regulates-vegf-a-induced-angiogenesis-through/)
- [Targeted methylation sequencing reveals dysregulated Wnt signaling in Parkinson disease](https://scholariq.org/papers/targeted-methylation-sequencing-reveals-dysregulated-wnt-signaling-in-parkinson/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.