# Ocular Disorders and Treatments

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/ocular-disorders-and-treatments/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on genetic and clinical studies related to ocular development, particularly microphthalmia, anophthalmia, and associated syndromes such as Fraser syndrome. It explores the genetic mutations in genes like SOX2 and BCOR, as well as the use of orbital implants in surgical management of eye malformations. The research also delves into epidermal adhesion and its role in ocular development. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12989 |
| Works | 102 |

## Topic papers all

Showing 15 of 102.

- [Mutations in SOX2 cause anophthalmia](https://scholariq.org/papers/mutations-in-sox2-cause-anophthalmia/)
- [Incidence of Uveal Melanoma in Europe](https://scholariq.org/papers/incidence-of-uveal-melanoma-in-europe/)
- [Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa.](https://scholariq.org/papers/morphometric-analysis-of-the-extramacular-retina-from-postmortem-eyes-with/)
- [Heterozygous Mutations of OTX2 Cause Severe Ocular Malformations](https://scholariq.org/papers/heterozygous-mutations-of-otx2-cause-severe-ocular-malformations/)
- [Intermediate-term clinical experience with the Ahmed Glaucoma Valve implant](https://scholariq.org/papers/intermediate-term-clinical-experience-with-the-ahmed-glaucoma-valve-implant/)
- [Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways](https://scholariq.org/papers/mutations-in-bmp4-cause-eye-brain-and-digit-developmental-anomalies-overlap/)
- [<i>SOX2</i> anophthalmia syndrome](https://scholariq.org/papers/i-sox2-i-anophthalmia-syndrome/)
- [Human scleral permeability. Effects of age, cryotherapy, transscleral diode laser, and surgical thinning.](https://scholariq.org/papers/human-scleral-permeability-effects-of-age-cryotherapy-transscleral-diode-laser/)
- [Scleral fixation of intraocular lenses using Gore-Tex suture: clinical outcomes and safety profile](https://scholariq.org/papers/scleral-fixation-of-intraocular-lenses-using-gore-tex-suture-clinical-outcomes/)
- [International Results with the Boston Type I Keratoprosthesis](https://scholariq.org/papers/international-results-with-the-boston-type-i-keratoprosthesis/)
- [SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development](https://scholariq.org/papers/sox2-plays-a-critical-role-in-the-pituitary-forebrain-and-eye-during-human/)
- [Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing](https://scholariq.org/papers/comprehensive-molecular-diagnosis-of-179-leber-congenital-amaurosis-and-juvenile/)
- [Comparative analysis of visual outcomes with 4 intraocular lenses: Monofocal, multifocal, and extended range of vision](https://scholariq.org/papers/comparative-analysis-of-visual-outcomes-with-4-intraocular-lenses-monofocal/)
- [Complications in the First 5 Years Following Cataract Surgery in Infants With and Without Intraocular Lens Implantation in the Infant Aphakia Treatment Study](https://scholariq.org/papers/complications-in-the-first-5-years-following-cataract-surgery-in-infants-with/)
- [A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life](https://scholariq.org/papers/a-comparison-of-grating-visual-acuity-strabismus-and-reoperation-outcomes-among/)

## Topic primary papers

Showing 15 of 20.

- [Mutations in SOX2 cause anophthalmia](https://scholariq.org/papers/mutations-in-sox2-cause-anophthalmia/)
- [Heterozygous Mutations of OTX2 Cause Severe Ocular Malformations](https://scholariq.org/papers/heterozygous-mutations-of-otx2-cause-severe-ocular-malformations/)
- [<i>SOX2</i> anophthalmia syndrome](https://scholariq.org/papers/i-sox2-i-anophthalmia-syndrome/)
- [SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development](https://scholariq.org/papers/sox2-plays-a-critical-role-in-the-pituitary-forebrain-and-eye-during-human/)
- [A practical guide to the management of anophthalmia and microphthalmia](https://scholariq.org/papers/a-practical-guide-to-the-management-of-anophthalmia-and-microphthalmia/)
- [SOX2 anophthalmia syndrome: 12 new cases demonstrating broader phenotype and high frequency of large gene deletions](https://scholariq.org/papers/sox2-anophthalmia-syndrome-12-new-cases-demonstrating-broader-phenotype-and-high/)
- [The Oculome Panel Test](https://scholariq.org/papers/the-oculome-panel-test/)
- [Outcomes of phacoemulsification and intraocular lens implantation in microphthalmos and nanophthalmos](https://scholariq.org/papers/outcomes-of-phacoemulsification-and-intraocular-lens-implantation-in/)
- [The Psychosocial Impact of Living with an Ocular Prosthesis](https://scholariq.org/papers/the-psychosocial-impact-of-living-with-an-ocular-prosthesis/)
- [Abnormal Foveal Avascular Zone in Nanophthalmos](https://scholariq.org/papers/abnormal-foveal-avascular-zone-in-nanophthalmos/)
- [MicroRNA-29 mediates TGFβ1-induced extracellular matrix synthesis by targeting wnt/β-catenin pathway in human orbital fibroblasts.](https://scholariq.org/papers/microrna-29-mediates-tgf-1-induced-extracellular-matrix-synthesis-by-targeting/)
- [Integrated versus non-integrated orbital implants for treating anophthalmic sockets](https://scholariq.org/papers/integrated-versus-non-integrated-orbital-implants-for-treating-anophthalmic/)
- [Enucleation and evisceration: indications, complications and clinicopathological correlations.](https://scholariq.org/papers/enucleation-and-evisceration-indications-complications-and-clinicopathological/)
- [Porous and nonporous orbital implants for treating the anophthalmic socket: A meta-analysis of case series studies](https://scholariq.org/papers/porous-and-nonporous-orbital-implants-for-treating-the-anophthalmic-socket-a/)
- [The UK National Artificial Eye Questionnaire Study: predictors of artificial eye wearers’ experience Part 2 – visual function and quality of life](https://scholariq.org/papers/the-uk-national-artificial-eye-questionnaire-study-predictors-of-artificial-eye/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.